Nottingham, England, United Kingdom · On-site
About Sygnature Discovery At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ s…
Skills: Biochemical Screening, Cellular Screening, Biophysical Screening, Assay Development, Drug Discovery
Macclesfield, England, United Kingdom · On-site
About Sygnature Discovery At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ s…
Skills: Cell Biology, Pharmacology, Biochemistry, Biophysics, Enzymology
Nottingham, England, United Kingdom · Hybrid
About Sygnature Discovery At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ s…
Skills: C-suite Support, Diary Management, Corporate Governance, Microsoft Office, Microsoft Teams
Montreal, Quebec, Canada · Hybrid
À propos de Sygnature Discovery Chez Sygnature Discovery, nous transformons la science en résultats exceptionnels. Pour nos partenaires, qui développent des médicaments capables de changer des vies. Et pour nos équipes, …
Skills: CRM Administration, NetSuite, ERP Systems, Data Entry, Data Management
Montreal, Quebec, Canada · On-site
Historique Sygnature Discovery est une organisation de recherche contractuelle intégrée de premier plan dans le domaine de la découverte de médicaments. Basée au Royaume-Uni et au Canada, elle a son siège à Nottingham et…
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Nottingham, England, United Kingdom · On-site
About Sygnature Discovery At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ s…
Skills: In Vivo Pharmacology, Kidney Disease Research, Inflammation Research, Metabolic Disease Research, Study Design
Nottingham, England, United Kingdom • On-site
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The role involves developing and delivering customized biological screening assays to support preclinical drug discovery campaigns. Responsibilities include designing experiments independently and presenting scientific findings to key project stakeholders.
Candidates should hold a PhD in a biology-related discipline or possess relevant industrial experience in drug discovery. Proficiency in biochemical, biophysical, or cellular technologies and the ability to develop novel assays are highly desired.
At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible.
We’re 700+ scientists from over 50 countries, working as one across Europe and North America. With no competing internal programs, we offer total confidentiality and commitment.
Over the past 20 years, we’ve earned a track record of real impact: 60+ advanced candidates, 250 patents filed, 200+ active projects. Over 90% of our customers choose to stay with us – from biotechs racing to clinic to pharma companies that need specialised expertise for targeted challenges.
Bioscientists at Sygnature Discovery play essential roles in supporting and leading integrated client projects as well as developing and delivering customised biological screening assays to drive structure-activity relationships for preclinical drug discovery campaigns.
We are seeking talented Scientists who can help push the boundaries of our capabilities by contributing to the discovery of new drugs across a broad range of projects, molecular targets, and therapeutic indications. You should have recently completed a PhD in a relevant Biology-related discipline that translates well to Bioscience-based drug discovery or have relevant industrial experience within a drug discovery environment. Please note that this is a full-time, fixed-term, lab-based position based at our Alderley Park site.
Whether you are a Scientist looking to transition from academia to the pharmaceutical industry and jumpstart your career in drug discovery, or a Senior Scientist who has a good understanding in the application of drug discovery and is seeking broader exposure to biology, disease areas, screening platforms, and therapeutic modalities - we would love to hear from you!
Undertakes training activities that will develop an understanding of biochemical, cellular, and biophysical screening techniques.
Deploys to client projects, developing and delivering bespoke screening assays as required.
Designs and executes experiments independently.
Identifies and solves problems associated with own experiments and those of other team members when appropriate.
Presents scientific findings, interpretations, and recommendations to key project stakeholders.
May take on a leadership role with significant level of technical and scientific supervision within Bioscience only projects.
Ideally you will be close to submission or have a PhD in a Biology-specific discipline with substantial practical research experience in areas that align with our project portfolio e.g. cell biology, pharmacology, biochemistry, biophysics, or enzymology. Relevant industry experience within a drug discovery environment will also be considered.
Experience of biochemical, biophysical or cellular technologies as applied to compound screening would be an advantage, and a strong scientific track record with experience built within a drug discovery environment is highly desirable
A strong interest in drug discovery, coupled with an awareness of current and emerging industry trends, is expected.
Ability to develop novel assays from first principles and interpret complex biological datasets.
Aptitude for proactive trouble-shooting and adoption of industry-leading practices for generation and analysis of robust scientific data.
Ability to work independently and as part of a larger team.
Excellent written and verbal communication skills and an ability to present complex scientific ideas and datasets to key stakeholders.
Willingness to learn new processes, interacting with state-of-the-art equipment and data analysis software.
🌴 25 days annual leave (plus bank holidays)
🏥 Private Medical Insurance
🛡️ Life Insurance
🎯 Employee Assistance Programme
⚖️ Enhanced Family Friendly Policies
💰 Sygnature Group Pension Scheme
💚 1 paid volunteer day per year
Please note: This advert may close early if we receive a high volume of applications. We encourage you to submit your application as soon as possible to avoid missing out on this opportunity.
#BeyondBoundaries
At Sygnature Discovery, a global drug discovery CRO, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ scientists from over 50 countries, working as one across Europe and North America. With no competing internal programs, we offer total confidentiality and commitment. Over the past 20 years, we’ve earned a track record of real impact: 60+ advanced candidates, 200+ patents filed, 200+ active projects. Over 90% of our customers choose to stay with us – from biotechs racing to clinic to pharma companies that need specialised expertise for targeted challenges. We go Beyond Boundaries to deliver speed without compromising on quality. Founded in 2004, we have delivered over 40 pre-clinical compounds, 21 clinical compounds, and our scientists are named on over 170 patent applications. We partner with global pharma, biotech, and NFP organizations, providing integrated drug discovery services from target identification through to candidate nomination. Our co-located teams are experts in protein science, chemistry, computational chemistry, in vitro biology, pharmacology, DMPK, form and formulation services, and project management, with a core therapeutic focus on oncology, inflammation and immunology, as well as neuroscience, metabolic diseases, respiratory, infectious diseases and fibrotic diseases.
Offices: BioCity, Pennyfoot Street, Nottingham, NG1 1GR, GB · 245 First Street, Cambridge, Massachusetts 02142, US · 611 Gateway Blvd, Suite 120, South San Francisco, California 94080, US · Alderley Park, Alderley Edge, England SK10 4TG, GB
#BeyondBoundaries
At Sygnature Discovery, a global drug discovery CRO, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ scientists from over 50 countries, working as one across Europe and North America. With no competing internal programs, we offer total confidentiality and commitment. Over the past 20 years, we’ve earned a track record of real impact: 60+ advanced candidates, 200+ patents filed, 200+ active projects. Over 90% of our customers choose to stay with us – from biotechs racing to clinic to pharma companies that need specialised expertise for targeted challenges. We go Beyond Boundaries to deliver speed without compromising on quality. Founded in 2004, we have delivered over 40 pre-clinical compounds, 21 clinical compounds, and our scientists are named on over 170 patent applications. We partner with global pharma, biotech, and NFP organizations, providing integrated drug discovery services from target identification through to candidate nomination. Our co-located teams are experts in protein science, chemistry, computational chemistry, in vitro biology, pharmacology, DMPK, form and formulation services, and project management, with a core therapeutic focus on oncology, inflammation and immunology, as well as neuroscience, metabolic diseases, respiratory, infectious diseases and fibrotic diseases.
Offices: BioCity, Pennyfoot Street, Nottingham, NG1 1GR, GB · 245 First Street, Cambridge, Massachusetts 02142, US · 611 Gateway Blvd, Suite 120, South San Francisco, California 94080, US · Alderley Park, Alderley Edge, England SK10 4TG, GB
