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$165k–$200k/yr
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Skills: Drug substance development, Upstream process development, CDMO management, Fusion protein, Biologics
Cambridge, Massachusetts, United States · Hybrid
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Cambridge, Massachusetts, United States · Remote OK
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Cambridge, Massachusetts, United States · Hybrid
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Cambridge, Massachusetts, United States · On-site
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Cambridge, Massachusetts, United States · Hybrid
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Cambridge, Massachusetts, United States · On-site
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Cambridge, Massachusetts, United States · Hybrid
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Cambridge, Massachusetts, United States · Hybrid
$145k–$196k/yr
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Cambridge, Massachusetts, United States · On-site
$75/hr–$110/hr
Tunnell Consulting is an employee-owned, life sciences management consulting firm. Known for solving complex problems in the life sciences, we support the mission and objectives of a variety organizations including biote…
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Cambridge, Massachusetts, United States · On-site
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Cambridge, Massachusetts, United States · Hybrid
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Cambridge, Massachusetts, United States · On-site
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Cambridge, Massachusetts, United States · Hybrid
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Cambridge, Massachusetts, United States · Hybrid
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Skills: Project management, Research, Writing, Editing, Fact-checking
Cambridge, Massachusetts, United States · Hybrid
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Cambridge, Massachusetts, United States · Hybrid
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Cambridge, Massachusetts, United States · On-site
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Cambridge, Massachusetts, United States · On-site
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Cambridge, Massachusetts, United States · On-site
$65k–$90k/yr
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Skills: Leadership, Management, Customer service, Sales, Communication
Cambridge, Massachusetts, United States • On-site
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The role involves leading the CMC execution strategy for a fusion protein drug substance program from late-phase development through PPQ. The lead will manage technical relationships with CDMO partners and collaborate with internal SMEs to ensure disciplined, on-schedule execution of manufacturing plans.
Candidates must hold a Ph.D. or M.S. in a relevant engineering field with extensive experience in upstream biologics process development. Proven expertise in late-phase process characterization, CDMO management, and regulatory documentation is required.
Description
Sr. Manager / Associate Director, Late-Phase Drug Substance PD/MSAT
At Merida Biosciences, we are pioneering true precision medicines for antibody-driven diseases. We specifically target pathogenic antibodies and their cellular sources with bespoke Fc biotherapeutics engineered to selectively eliminate the root causes of autoimmune and allergic diseases, achieving deep, durable responses while preserving essential immunity. We are passionate about transforming treatment paradigms across the spectrum of antibody-driven diseases and we are looking for equally passionate individuals to join our mission.
We are seeking a technically driven and strategically minded Sr. Manager / Associate Director to serve as our late-phase drug substance PD/MSAT lead, reporting to the Head of Drug Substance . This individual will own the CMC execution strategy for a fusion protein drug substance program from late-phase development, PC through PPQ and will serve as the primary technical interface with our CDMO partner for operations. Working closely with our upstream and downstream process development SMEs and Head of Drug Substance, this person will help shape the broader CMC strategy and ensure disciplined, on-schedule execution of late-phase plans.
The candidate will also participate in late-phase CDMO vendor evaluation, contribute to early-phase process development work, and gain hands-on experience defining work packages that advance molecules from candidate selection to IND. This is an opportunity for a seasoned upstream engineer to operate with high autonomy and real ownership in a lean, science-first startup environment.
Requirements
Merida Biosciences is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
Compensation: We understand that compensation is an important part of considering a new opportunity. Our goal is to be transparent so there are no surprises at the end of the process, and you can feel confident that your offer is both fair and equitable. To support that, we’re sharing our hiring range for this role upfront: typically for the Senior Manager/Associate Director we target $165,000 to $200,000. The final offer will take into account a number of factors, including your skills, experience, location, market data, and internal equity. Along with a competitive salary, we’re proud to offer a comprehensive benefits package designed to support you both personally and professionally.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.
Merida Biosciences is a biotechnology company pioneering a new class of precision therapeutics designed to selectively and durably eliminate pathogenic antibodies that drive disease. The company is advancing a robust pipeline to precisely eliminate the root cause of multiple autoimmune and allergic conditions that are inadequately treated today. Its lead program is designed to specifically and rapidly clear the pathogenic autoantibodies that cause Graves' disease, an autoimmune disorder that affects the thyroid gland. Merida was publicly launched in April 2025 and is based in Cambridge, MA. For more information about Merida, visit www.meridabio.com.
Offices: 500 Technology Sq, Cambridge, Massachusetts 02139, US
