Legend BiotechSomerset, New Jersey, United States · Hybrid
$127k–$167k/yr
Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy throug…
Skills: Toxicology, Pharmacology, Nonclinical Development, Cell and Gene Therapy, CRO Management
Legend BiotechPhiladelphia, Pennsylvania, United States · On-site
Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy throug…
Skills: Lentiviral Vector Production, Upstream Process Development, Molecular Biology, Bioreactor Operations, Design of Experiments (DoE)
Legend BiotechPhiladelphia, Pennsylvania, United States · On-site
$96k–$126k/yr
Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy throug…
Skills: Viral vector production, Mammalian suspension cell culture, Transient transfection, Upstream bioprocess development, Molecular biology
Legend BiotechPhiladelphia, Pennsylvania, United States · On-site
$111k–$145k/yr
Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy throug…
Skills: In Vitro Functional Assays, CAR Design, T Cell Engineering, Cancer Cell Line Maintenance, Multicolor Flow Cytometry
Legend BiotechPhiladelphia, Pennsylvania, United States · On-site
$111k–$145k/yr
Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy throug…
Skills: CAR-T Cell Therapy, Flow Cytometry, In Vivo Efficacy Studies, Lentiviral Transduction, CRISPR/Cas9
Philadelphia, Pennsylvania, United States · On-site
Performs a wide variety of laboratory procedures using both manual and automated methods. Is expected to show a considerable degree of independent judgment regarding the performance and reporting of results. Actively par…
Skills: Laboratory procedures, Manual laboratory methods, Automated laboratory methods, Quality improvement, Independent judgment
Philadelphia, Pennsylvania, United States · On-site
The Wistar Institute has an opening for a Post-Doctoral Fellow to join the laboratory of Dr. Brian Fuglestad as part of the Center for Advanced Therapeutics. The Fuglestad lab is interested in expanding molecular study o…
Skills: Synthetic chemistry, Medicinal chemistry, Biophysical protein assays, Biochemical protein assays, Inhibitor design
Philadelphia, Pennsylvania, United States · On-site
The Wistar Institute is seeking a highly motivated Post-Doctoral Fellow to work in the laboratory of Dr. Alessandro Gardini in the Ellen and Ronald Caplan Cancer Center at The Wistar Institute. The Gardini lab is interes…
Skills: Functional genomics, Bioinformatics analysis, Biochemistry, Proteomics, Cell biology
Philadelphia, Pennsylvania, United States · On-site
Job Details Clinical Research Coord - SR Job Description Works independently or with minimal supervision to oversee the day-to-day activities of a clinical trial in accordance with Good Clinical Research Practice (GCP). …
Skills: Clinical research, Good clinical practice, Protocol coordination, Data management, Biological specimen management
Philadelphia, Pennsylvania, United States · On-site
Performs a wide variety of laboratory procedures using both manual and automated methods. Is expected to show a considerable degree of independent judgment regarding the performance and reporting of results. Actively par…
Skills: Laboratory procedures, Manual laboratory methods, Automated laboratory methods, Quality improvement, Data reporting
Philadelphia, Pennsylvania, United States · On-site
Job Details Administers and scores psychological test batteries evaluate cognitive, neuropsychological, academic, behavioral, and emotional status in order to assist the Neuropsychologists in evaluation and treatment dec…
Skills: Neuropsychological testing, Psychological test administration, Test scoring, Behavioral observation, Clinical supervision
Philadelphia, Pennsylvania, United States · On-site
The Department of Clinical Genetics of Fox Chase Cancer Center invites applications for a full-time Genetic Counselor Manager position. Our Risk Assessment Program was established in 1991 as one of the first in the natio…
Skills: Genetic Counseling, Clinical Operations Management, Cancer Genetics, Staff Hiring and Retention, Patient Care Coordination
Wilmington, Delaware, United States · On-site
Process Implementation Lead ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values-driven organisation, integ…
Skills: Executive support, Project coordination, Calendar management, Travel coordination, Expense reporting
Philadelphia, Pennsylvania, United States · On-site
Performs a variety of generally routine duties involved in the drawing and collection of blood specimens from identified patients. Records necessary information following established methods and procedures and all hospit…
Skills: Phlebotomy, Specimen collection, Point of care testing, Laboratory procedures, Specimen processing
Philadelphia, Pennsylvania, United States · On-site
We Are Committed to an Inclusive Workplace At the Philadelphia Museum of Art, we actively seek to employ a diverse group of people who embody our organizational values. We welcome and encourage individuals of all backgro…
Skills: Art history, Curatorial research, Cataloguing, Collection management, Exhibition planning
Philadelphia, Pennsylvania, United States · On-site
Job Details Full Time General Nephrology Faculty Position at Jefferson Einstein Philadelphia Job Description Jefferson Einstein Philadelphia is seeking a board certified/eligible nephrologist to join our Department of Ne…
Skills: Nephrology, Clinical care, Inpatient consults, Dialysis, Teaching
Philadelphia, Pennsylvania, United States · On-site
Job Details The laboratory of Dr. Jianping Li (jianpinglilab.com) at the Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Thomas Jefferson University (TJU) is seeking a highly motivated postdoctoral fellow to join ou…
Skills: Molecular biology, T-cell immunology, Cancer biology, Chromatin regulation, Cancer epigenetics
Philadelphia, Pennsylvania, United States · On-site
Performs standard diagnostic tests and special studies, which involve the operation of EEG equipment. Identifies artifact, describes abnormal clinical manifestations, assists in the evaluation of patients, collects data …
Skills: EEG Equipment Operation, Artifact Identification, Clinical Manifestation Analysis, Patient Evaluation, Quality Assurance
Children's Hospital of Philadelphia Research InstitutePhiladelphia, Pennsylvania, United States · On-site
$76k–$97k/yr
SHIFT: Day (United States of America) Seeking Breakthrough Makers Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspi…
Skills: Data management, Data governance, Database design, Clinical data registries, Data validation
Philadelphia, Pennsylvania, United States · On-site
Job Details The research assistant intermediate carries out experiments as part of a team of bio-medical researchers to investigate the molecular mechanisms mediating diseases. They will also record and analyze experimen…
Skills: Laboratory experiments, Data analysis, Molecular biology, Research protocols, Literature search
Legend Biotech
Somerset, New Jersey, United States • Hybrid
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Support nonclinical development and safety assessments for cell and gene therapy programs from discovery through IND-enabling stages. Design and interpret safety, pharmacology, and pharmacokinetic studies while collaborating with cross-functional teams and CROs.
Requires a Ph.D., DVM, or PharmD in Toxicology, Pharmacology, or a related field with at least 5 years of biotech or pharmaceutical R&D experience. Proficiency in GLP toxicology, regulatory expectations, and experience with advanced therapeutic platforms is highly desired.
Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.
Legend Biotech is seeking a Sr. Scientist, Toxicology as part of the Early Drug Development team based in Somerset, NJ or Philadelphia, PA.
Role Overview
Legend Biotech is seeking a Sr. Scientist, Toxicology to support nonclinical development and safety assessment across cell and gene therapy programs. This individual will contribute to nonclinical strategy from discovery through IND-enabling development and support regulatory submissions for innovative advanced therapies. The role requires scientific expertise in toxicology, a foundation in pharmacology, understanding of regulatory expectations, and the ability to work effectively across cross-functional teams in a fast-paced biotech environment.
Key Responsibilities
Requirements
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The base pay range below is what Legend Biotech USA Inc. reasonably expects to offer at the time of posting. Actual compensation may vary based on experience, skills, qualifications, and geographic location. The company reserves the right to modify this range as needed and in accordance with applicable laws.
Other Types of Pay: Performance-based bonus and/or equity is available to employees in eligible roles.
Benefits and Paid Time Off: Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.
Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
Work Authorization & Employment Eligibility
Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.
Legend Biotech is a global, commercial-stage biotechnology company developing and manufacturing novel therapies. We explore and apply innovative technologies to deliver cutting-edge options for patients around the world. Our corporate headquarters is located in Somerset, NJ, and our manufacturing footprint includes facilities in the United States, China and the Belgium.
Offices: 2101 Cottontail Lane, Somerset, New Jersey 08873, US · 10 Knightsbridge Rd, Piscataway, New Jersey 08854, US · Esplanade, Gaston Crommenlaan 8, Ghent, 9050, BE · 10A Ballymoss Road, Sandyford Business Park, Dublin, IE · No. 6 Building, Life Science TechTown 568 Longmian Avenue Jiangning District, Nanjing , CN
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