Cambridge, Massachusetts, United States · On-site
Alva Energy is scaling nuclear power uprates and related first-of-a-kind deployment projects across the U.S. power fleet. We are hiring a Senior NSSS Integration Engineer to lead integration of nuclear steam supply syste…
Skills: NSSS Integration, Nuclear Power Plant Operations, Systems Engineering, Design Engineering, 4-loop PWR Operation
Cambridge, Massachusetts, United States · Hybrid
$159k–$219k/yr
About This Role: As a Principal Manufacturing Engineer, you will be an integral part of the Implantable Device Unit and Device Development and Manufacturing team, within the Product Delivery Solutions organization. Your …
Skills: Manufacturing Strategy, Process Validation, Class III Implantable Devices, Drug Delivery Systems, FDA QSR
Cambridge, Massachusetts, United States · On-site
Your Impact at LILA Lila is actively seeking talented and motivated students to join us in ushering in a new era of scientific intelligence. Throughout your co-op, you'll have the opportunity to learn from and collaborat…
Skills: Software Development, Programming, Prototyping, Lab Automation, Hardware Tooling
Cambridge, Massachusetts, United States · On-site
Your Impact at LILA Lila Sciences is building a new Customer Delivery & Success function, and we're looking for an Associate Director / Director, Customer Program Management to lead delivery for our physical sciences cus…
Skills: Program Management, Customer Relationship Management, Cross-functional Leadership, Strategic Judgment, Operational Excellence
Cambridge, Massachusetts, United States · On-site
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Digital Content Creation, Research Translation, Web Strategy, Data Visualization, AI Tools
Cambridge, Massachusetts, United States · On-site
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Conservation Treatment, Preventive Care, Condition Reporting, Project Management, Technical Examination
Cambridge, Massachusetts, United States · On-site
Your Impact at LILA Lila Sciences is building the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science. We are pioneering a new age of discovery by applying AI…
Skills: Python, Machine Learning, Data Pipelines, Anomaly Detection, SCADA
Cambridge, Massachusetts, United States · On-site
Position Title: Data Scientist Contractor, Computational Biology (6-month contract) Reports To: Senior Director, Head of Data Sciences Location: Cambridge, MA Join the adventure! CAMP4 is seeking a Data Science Contracto…
Skills: Computational Biology, Bioinformatics, Next-Generation Sequencing, RNA-seq, scRNAseq
Cambridge, Massachusetts, United States · Hybrid
$108k–$176k/hr
Job Title: Nonclinical Operational Specialist – Contractor Location: Hybrid Job Type: Contract, paid hourly Contract Duration: 1 year with potential for conversion to permanent employee in the future. Position Summary We…
Skills: CRO Management, DMPK, Toxicology, GLP Compliance, Project Management
Cambridge, Massachusetts, United States · Hybrid
$122k–$166k/yr
Overview: We are seeking an individual for the role of Manager – Clinical Supply Chain, Operations. In this position, you will play a pivotal role in ensuring reliable, compliant execution of clinical supply across progr…
Skills: Clinical Supply Chain Management, IRT/IXRS, Inventory Management, Global Distribution, GMP/GxP/GCP
Cambridge, Massachusetts, United States · Hybrid
$258k–$405k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: Clinical Development Strategy, Medical Monitoring, Protocol Development, Regulatory Affairs, Matrix Team Leadership
Cambridge, Massachusetts, United States · Hybrid
$154k–$243k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: Brand Management, Commercial Strategy, Pre-commercialization Planning, Market Development, Cross-functional Collaboration
Cambridge, Massachusetts, United States · Hybrid
$145k–$172k/yr
Who is BlueRock? BlueRock Therapeutics LP is a clinical stage cell therapy harnessing the power of cell therapy to create a pipeline of new medicines for people suffering from neurological and ophthalmic diseases. Two of…
Skills: External Partner Management, Contract Negotiation, Budget Forecasting, Risk Management, GxP Guidelines
Cambridge, Massachusetts, United States · Hybrid
$80k–$131k/yr
We are seeking a highly motivated and innovative Senior Associate Scientist to join our discovery research team at Regeneron Cell Medicines. You will be performing immunological functional assays for analyzing geneticall…
Skills: Multi-color Flow Cytometry, Primary Human T Cell Isolation, Mammalian Cell Culture, CAR-T Therapy, TCR T Cells
Cambridge, Massachusetts, United States · On-site
$47/hr
Site: The Spaulding Rehabilitation Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance…
Skills: Clinical Patient Care Assessment, Respiratory Therapy Procedures, Patient Care Planning, Mechanical Ventilation, Patient Education
Cambridge, Massachusetts, United States · On-site
$142k–$192k/yr
Career CategoryProcess DevelopmentJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with…
Skills: Small Molecule Analysis, Chromatographic Techniques, Spectroscopic Techniques, Separation Science, Process Analytical Technologies (PAT)
Thousand Oaks, California, United States · On-site
$126k–$171k/yr
Career CategoryScientificJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious …
Skills: Analytical Chemistry, Organic Chemistry, HPLC, UPLC, Mass Spectrometry
Cambridge, Massachusetts, United States · On-site
$206k–$298k/yr
Job Title: US Senior Medical Director, Neurology Location: Cambridge, MA About the Job: Our Team: This position will report into the US Medical Next Gen Immunology team, a segment of the Medical Specialty Care organizati…
Skills: Strategic Leadership, Medical Affairs, People Management, Clinical Development, Stakeholder Management
Cambridge, Massachusetts, United States · On-site
$200k–$240k/yr
Description At Merida Biosciences, we are pioneering true precision medicines for antibody-driven diseases. We specifically target pathogenic antibodies and their cellular sources with bespoke Fc biotherapeutics engineer…
Skills: Regulatory Submission Planning, eCTD Publishing, Lifecycle Management, Project Management, Regulatory Compliance
Cambridge, Massachusetts, United States · Hybrid
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Agreement Negotiation, Sponsored Research Administration, Compliance, Subcontract Management, Regulatory Knowledge
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Lead the integration of Nuclear Steam Supply System (NSSS) requirements into uprate execution programs, focusing on 2TGP integration and plant modifications. Act as the technical bridge between plant operations, safety analysis, and external partners to ensure design consistency and operational practicality.
Requires a Bachelor's degree in Mechanical, Nuclear, or related engineering with over 10 years of experience in nuclear plant operations or systems engineering. Strong expertise in 4-loop PWR systems and experience with plant transients and safety analysis is essential.
Alva Energy is scaling nuclear power uprates and related first-of-a-kind deployment projects across the U.S. power fleet. We are hiring a Senior NSSS Integration Engineer to lead integration of nuclear steam supply system requirements into Alva’s uprate execution programs, with particular focus on 2TGP integration, plant modifications, and coordination across internal and external engineering teams.
This role is a senior technical leadership position for an engineer who can bridge plant operations, systems engineering, transient response, and implementation planning. You will work closely with Alva’s process engineering team, I&C engineering, safety analysis team, EPC partner, utility partner, and NSSS vendor to ensure uprate-related system integration is technically sound, operationally practical, and aligned with plant safety and design basis requirements.
Lead NSSS integration for Alva’s 2TGP and related uprate projects, ensuring NSSS requirements are correctly translated into system design, controls philosophy, and implementation scope.
Work with Alva’s 2TGP process engineering team, EPC partner, I&C manager, and DuoSync developer to define and manage the NSSS-side requirements needed for integrated plant operation.
Develop and define operating strategies and procedures for startup, shutdown, step load changes, ramping, and other transient operating conditions relevant to two turbine plant operation.
Serve as the technical bridge between plant operations, process design, controls development, and engineering implementation for NSSS-related system integration.
Partner with Alva’s safety analysis team to review safety analysis outputs and determine required plant modifications, design updates, and engineering actions.
Support engineering definition and review of NSSS-related plant modifications, including containment, ECCS, auxiliary feedwater, and other systems.
Coordinate technical interfaces among the utility partner, EPC partner, internal engineering team, and NSSS vendor to resolve design, operational, and licensing-basis issues.
Review design packages, technical deliverables, and modification concepts to ensure consistency with plant operating requirements, transient performance expectations, and NSSS design constraints.
Bachelor’s degree in Mechanical Engineering, Nuclear Engineering, or related engineering discipline.
10+ years of experience in nuclear power plant operations, systems engineering, design engineering, or plant modification programs.
Strong background in 4-loop PWR operation and systems engineering, ideally with direct experience supporting plant transients, operating procedures, and system response.
Demonstrated experience working across NSSS and balance-of-plant interfaces in an operating plant or major plant modification environment.
Familiarity with safety analysis and the engineering implications of design-basis and transient performance requirements.
Ability to work effectively across process engineering, I&C, safety analysis, EPC, utility, and vendor organizations.
Breadth of experience in mechanical design, project coordination, and cross-functional technical leadership.
Strong written and verbal communication skills, including the ability to lead technical discussions and drive alignment across diverse stakeholders.
Willingness to travel periodically to utility, partner, and supplier sites as needed.
Prior licensed operator, SRO, or equivalent plant operations background at a 4-loop PWR.
Experience supporting uprates, major plant modifications, or first-of-a-kind integration efforts.
Familiarity with startup test planning, transient analysis inputs, or control system integration in nuclear plant environments.
Charting the fastest path to new nuclear.
Alva Energy is on a mission to lead the fastest, most affordable nuclear power deployment in history. As the first independent nuclear project management and delivery organization, we're transforming how nuclear projects are executed, bringing unprecedented speed and efficiency to nuclear energy deployment.
Offices: 1 Broadway, Floor 14, Cambridge, Massachusetts 02142, US
Based on 747 listings with disclosed salaries, most science & research jobs in Cambridge, MA pay between $90k–$267k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 915 open science & research positions in Cambridge, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Sanofi, Novartis, Harvard Division of Medical Sciences, Draper, Lila Sciences, among others. Browse the listings above to see every active employer.
Yes — 386 of the 915 open science & research positions offer remote or hybrid work (44 remote, 342 hybrid).
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