Research Scientist, Lentiviral Vector Purification and Analytics
Cambridge, Massachusetts, United States · On-site
$67k–$151k/yr
Mid level$4.5B raised
Job Description Summary The Lentiviral Vector (LVV) Team in the Biologics Research Center (BRC) at Novartis, Cambridge, MA is seeking a highly motivated Research Scientist with experience in production and purification o…
Cambridge, US; Gaithersburg, US; London, United Kingdom | full time | Job ID: 11272 About the Role: As the Global Medical Affairs Team and Asset Leader, you will take the helm of a Medical Affairs Team (MAT), crafting an…
Skills: Oncology, Medical Affairs, Strategic Planning, Cross-functional Leadership, Evidence Generation
Make your mark for patients To strengthen our Non-Clinical Safety Evaluation group within Early Clinical Development and Translational Science, we are looking for a talented individual for the role of Non-Clinical Safety…
Skills: Toxicology, Pharmacology, Regulatory Toxicology, Non-clinical Safety, Drug Development
Senior Principal Scientist - Translational Muscle Biology
Cambridge, Massachusetts, United States · Hybrid
Senior+$202M raised
Make your mark for patients We are seeking a Senior Principal Scientist to join the US Neuromuscular group based in Cambridge, MA and help drive translational biology drug discovery efforts with an emphasis on muscle bio…
Skills: Muscle biology, Translational biology, Drug discovery, Team leadership, Project management
New ER Doctor (NERD) Program: Starts October 2026, Practicing Veterinarians - Cambridge, MA
Cambridge, Massachusetts, United States · On-site
Mid level
ABOUT VEG In 2014, VEG was born with a mission to help people and their pets when they need it most. This meant challenging the status quo and fixing everything that was wrong with the ER experience. Since then, we’ve ex…
Skills: Emergency Medicine, Veterinary Surgery, Endoscopy, Exotic Animal Care, Client Communication
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
At MacroCycle, we’re building a new approach to textile recycling. Today, most textiles end up in landfills or are incinerated, but our SolvoGenesis™ technology transforms that waste back into high-quality polyester fibe…
Skills: Polymer chemistry, Separation science, Chemical engineering, Materials science, PET
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Overview The mission of DMPK is to enable efficient and successful drug discovery and development of siRNA and other therapeutic candidates by characterizing and interpreting ADME (absorption, distribution, metabolism, a…
Skills: Quantitative pharmacology, PK/PD modeling, Pharmacokinetic data analysis, ADME, Drug disposition
Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitmen…
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Associate Director, GDE Functional Learning & Engagement
London, England, United Kingdom · On-site
$146k–$234k/yr
Senior+$2.0B raised
Cambridge, US; Gaithersburg, US; London, United Kingdom; Mainz, Germany; New Jersey, US | full time | Job ID: 11685 About the Role: As Associate Director for Functional Learning & Engagement (FLE), you play a pivotal rol…
Skills: Training management, Learning and development, Communications, Change management, Instructional design
Cambridge, Massachusetts, United States · Remote Solely
Senior$776M raised
Associate Director, Value, Access & Pricing (Ex-US) Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengt…
Does it excite you to build a strong foundation in modern protein purification and analytical technologies, and are you eager to grow your scientific career from the ground up? If this sounds like you, and you are ready …
Skills: Protein purification, FPLC, Size-exclusion chromatography, Ion-exchange chromatography, Affinity chromatography
Does it excite you to work at the frontier of antibody and binder discovery, and do you have hands-on experience with yeast surface display technology? If this sounds like you, and you are ready to help build a new disco…
Skills: Yeast surface display, Antibody discovery, Protein engineering, FACS, Library construction
Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful a…
Skills: System Integration, System Testing, Verification And Validation, Functional Simulation, Performance Evaluation
Does it excite you to be the go-to purification expert delivering high-purity samples for cutting-edge structural biology and mass spec studies? If this sounds like you, and you are ready to bring deep purification exper…
Skills: Protein purification, Bioconjugate purification, SEC, IEX, Affinity chromatography
Does it excite you to work at the frontier of peptide and mini-protein drug discovery, and do you have hands-on experience with mRNA display technology? If this sounds like you, and you are ready to help build a new disc…
Skills: mRNA display, Peptide discovery, Mini-protein discovery, In vitro transcription, In vitro translation
Biogen
Sr. Scientist, Biologics Engineering
Cambridge, Massachusetts, United States · Hybrid
$124k–$166k/yr
Senior
About This Role The BioDesign group at Biogen is seeking an experienced and highly motivated scientist to contribute to the discovery and development of innovative biologic therapeutics. The Sr. Scientist will contribute…
Skills: Molecular biology, Protein engineering, Antibody engineering, Mammalian cell culture, Recombinant protein expression
Allina Health System, Inc.
Hematology Oncology Nurse Practitioner or Physician Assistant
Cambridge, Massachusetts, United States · On-site
$135k–$164k/yr
Entry level
Location Address: 701 South Dellwood Cambridge, MN 55008-1920 Date Posted: August 14, 2026 Department: 31002908 AHCI Cancer Ctr Cambridge ANW Shift: Day (United States of America) Shift Length: 8 hour shift Hours Per Wee…
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Medical Science Liaison Respiratory - Pulmonary W PA, VA, W VA
Cambridge, Massachusetts, United States · Remote OK
$146k–$211k/yr
Mid level$9.7B raised
Job title: Medical Science Liaison Respiratory - Pulmonary W PA, VA, W VA Location: Cambridge, MA About the Job The Medical Science Liaison (MSL) is field-facing role whose main objectives are to: · Be the trusted scient…
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$67k–$151k/yr
Full-time
bachelor degree, postgraduate degree
Health insurance, Life insurance, Disability benefits, 401(k) with company contribution and match, Vacation, Personal days
Posted 26d ago
~40 hrs/week
Responsibilities
The Research Scientist will execute laboratory activities related to lentiviral vector purification, including clarification, chromatography, and TFF. They will also perform analytical methods to assess vector quality and contribute to the development and optimization of viral vector processes.
Requirements
Candidates must hold a Bachelor's or Master's degree in bioengineering, virology, or a related field with 1–3 years of experience in protein or viral vector purification. Proficiency in chromatography, filtration techniques, and strong communication skills are essential for this lab-based role.
Full job description
Job Description Summary
The Lentiviral Vector (LVV) Team in the Biologics Research Center (BRC) at Novartis, Cambridge, MA is seeking a highly motivated Research Scientist with experience in production and purification of viral vectors to join our team. In this role, you will play a key part in advancing our Cell and Gene Therapy research initiatives and contributing to groundbreaking research in CAR-T cell therapy.
Job Description
Internal Job Title: Research Scientist I/II
Position Location: Cambridge, MA, onsite
** This role is based in Cambridge, MA/USA. Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.
Join a collaborative team at the forefront of cell and gene therapy research. As a Research Scientist focused on lentiviral vector purification and analytics, you will apply hands-on laboratory expertise to help develop, optimize, and characterize viral vector processes that support next-generation CAR-T programs. This role offers the opportunity to contribute directly to innovative science, work across purification and analytical workflows, and help advance high-quality research materials that enable transformative therapeutic approaches.
Key responsibilities:
This is a lab-based position that requires hands-on execution of activities related to lentiviral vector purification including clarification, chromatography and TFF.
Execute analytical methods (molecular- and cell-based) to assess quality of the purified vector.
Write and review protocols, technical reports, and technology transfer documents with supported conclusions and recommendations.
Write and review SOPs, instrument procedures, and other lab documents.
Plan and prioritize work to meet goals while managing multiple research activities.
Support experimental design, data analysis, and troubleshooting.
Identify root causes, implement solutions, and verify effectiveness.
Present scientific data and contribute openly to discussions.
Document experimental procedures and processes thoroughly.
Collaborate across teams, share knowledge, and train team members in technical areas as needed.
Essential Requirements:
BS or MS in bioengineering, virology, or related field, with relevant lab experience. This is not a PhD-level position.
1–3 years of experience in protein and/or viral vector purification.
Hands-on experience with chromatography and filtration techniques, including TFF and depth filtration.
Strong coordination, communication, collaboration, learning agility, and self-motivation.
Proficiency with Word, Excel, PowerPoint, and GraphPad Prism.
Excellent oral, written, and interpersonal communication skills.
Desirable Requirements:
BSL2 experience with AAV, lentiviral, or retroviral vector production.
Proficiency in aseptic technique, cell culture, molecular biology, and analytical testing.
Bioreactor experience.
The salary for this position is expected to range between $66,800 and $124,000 per year for Research Scientist I, and between $81,200 and $150,800 per year for Research Scientist II. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Salary Range
$66,800.00 - $124,000.00
Skills Desired
Algorithms, Analytical Thinking, Chemical Biology, Clinical Research, Clinical Trials, Collaboration, Curious Mindset, Data Analysis, Detail-Oriented, Ethics, Hypothesis Testing, Immunology, Mammalian Cell Culture, Medical Research, Molecular Biology, Science
Related keywords
Lentiviral VectorPurificationAnalyticsBiologicsCAR-TCell TherapyGene TherapyChromatographyTFFDepth FiltrationMolecular BiologyCell CultureAseptic TechniqueBioreactorSOPProtocol Development
Novartis is an innovative medicines company. Every day, working to reimagine medicine to improve and extend people’s lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 250 million people worldwide.
Find out more at https://www.novartis.com
See our community guidelines: https://go.novartis.social/3Nboxki
Offices: Novartis Campus, Basel, Baselstadt 4002, CH · One Health Plaza, East Hanover, NJ 07936, US · Calle 93B S-31, Bogota, Bogota, D.C. 110541, CO · Merrion Road, Dublin, County Dublin, IE · Na Pankraci 1724/129, Prague, Prague 140 00, CZ
CardiovascularImmunologyNeuroscienceSolid TumorsHematologyChemistryxRNARadioligandand Gene and cell therapyHealth Care
How much do Science & Research jobs in Cambridge, MA pay?
Based on 1051 listings with disclosed salaries, most science & research jobs in Cambridge, MA pay between $90k–$269k per year. Individual offers vary with seniority, company size, and specialization.
How many Science & Research jobs are open in Cambridge, MA right now?
There are currently 1,276 open science & research positions in Cambridge, MA listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in Cambridge, MA?
Companies currently hiring include Novartis, Draper, Harvard Division of Medical Sciences, Sanofi, Flagship Pioneering, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in Cambridge, MA?
Yes — 497 of the 1276 open science & research positions offer remote or hybrid work (54 remote, 443 hybrid).
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