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Full-time
postgraduate degree
Posted 6d ago
~40 hrs/week
Remote in Basel, Basel-Stadt, Switzerland
Responsibilities
Lead the definition and execution of the economic modeling strategy to produce high-quality health economic models across the company's oncology portfolio. This includes overseeing HTA submissions, payer evidence generation, and the integration of evolving HTA guidelines.
Requirements
Requires an advanced degree (Masters or PhD) in health economics or a related field with 13-15+ years of relevant experience in pharmaceutical economic modeling. Candidates must have a proven track record in developing cost-effectiveness models and supporting global HTA submissions.
Full job description
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
The Senior Director of Economic Modeling is responsible for defining and executing the economic modeling strategy to produce high quality health economic models & modeling strategies across Rev Meds portfolio. This is an exceptional opportunity to contribute to the advancement of healthcare by providing evidence that can shape the future of patient care in Oncology.
Key Strategic Responsibilities:
Lead the development of strategic and operational plans for health economic modeling within Global HEOR & RWE (e.g., early and submission cost-effectiveness / utility models, budget impact models, and country adaptations) while ensuring alignment with Integrated Evidence Plans and appropriate Global stakeholders.
Partner with Global HEOR & RWE Executive Directors on core health economic modeling plans to support HTA, payer, and other access stakeholder assessments, submissions, negotiations, including associated value/HTA deliverables and publications to meet business and access objectives.
Provide strategic, methodological and analytical leadership to teams and countries for adaptation of economic models for local HTA submissions.
Lead the development of an approach to monitor, educate and integrate evolving HTA guidelines, payer requirements, and methodologic advancements related to economic modeling.
Lead the development of robust governance, compliance, and readiness for all economic modeling activities by adhering to processes, guidelines, and project management standards.
Represent Rev Med in global external working groups regarding modeling standards and innovation (e.g., ISPOR Special Interest groups).
Key Operational Responsibilities:
Support design and development of economic models from start to finish for products across Rev Meds portfolio.
Direct statistical analyses of real-world data and clinical trial data (in collaboration with biostatistics) to generate inputs including treatment effects, survival extrapolations, resource use, and health utility estimates.
Design evidence synthesis, including network meta-analysis (NMA), and matching adjusted indirect comparisons (MAIC) to inform comparative effectiveness.
Required Skills, Experience and Education:
Advanced degree (Masters or PhD) in health economics, econometrics, biostatistics, mathematics, engineering or related field (DrPH, PharmD).
Minimum of 15 years with a Masters (or 13+ years with a PhD/PharmD/DrPH) of relevant experience in economic modeling in the pharmaceutical, biotech, or consulting setting.
Hands on experience in developing cost-effectiveness, budget impact models as well as NMA/MAIC.
Track record of high impact publications in economic modeling for global access decision-makers.
Experience supporting HTA submissions and payer evidence generation.
Strong written and interpersonal communication skills, with an ability to present complex technical information clearly.
Proven leadership and ability to influence others without direct reporting relationships.
Comfortable working in a global team across time zones.
Preferred Skills:
Experience in oncology economic modeling is highly desirable, especially related to gastrointestinal and thoracic malignancies.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].#LI-Remote #LI-LO1
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.
Revolution Medicine enables physicians to integrate personalized medicine into their practices in order to more effectively treat patients.
Our genes play an important role in determining how we respond to about 75% of prescription drugs. Scientific research has demonstrated which genes predict these responses. According to the American Medical Association (AMA), 98% of physicians agree that knowing a patient’s genetic profile would help in prescribing medications. Yet, 90% of physicians do not feel they are adequately informed about how to apply genetic testing to treatment decisions.
Our mission is to improve the quality of patient care by helping doctors determine optimal treatment strategies and more accurately predict treatment responses. Revolution Medicine has developed ScriptMatch, an analytical process that enables physicians to easily incorporate genetic testing into their practices.
Our company solves a major issue in the clinical market and addresses an emerging trend in patient-driven healthcare: having clinical results that become part of the medical record and applicable to future treatments.
How many Science & Research jobs are open in Basel, Switzerland right now?
There are currently 254 open science & research positions in Basel, Switzerland listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in Basel, Switzerland?
Companies currently hiring include Novartis, Roche, Universitätsbibliothek Basel, Revolution Medicine, Ridgeline Discovery, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in Basel, Switzerland?
Yes — 98 of the 254 open science & research positions offer remote or hybrid work (9 remote, 89 hybrid).
How do I apply for Science & Research jobs in Basel, Switzerland?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.