Cambridge, Massachusetts, United States · On-site
$90k–$166k/yr
Band Level 3 Job Description Summary LI#-Onsite Location: Cambridge Internal Title: Senior Scientist I Support discovery and development projects through the design, development, and execution of in-vitro ADME assays, wh…
Skills: ADME Assays, Metabolic Stability, Permeability Assays, Lab Automation, LCMS-MS
Cambridge, Massachusetts, United States · On-site
$90k–$166k/yr
Job Description Summary LI#-Onsite Location: Cambridge Internal Title: Senior Scientist I Support discovery and development projects through the design, development, and execution of in-vitro ADME assays, while building …
Skills: ADME Assays, Metabolic Stability, Permeability Assays, Lab Automation, LCMS-MS
Cambridge, Massachusetts, United States · Hybrid
$168k–$210k/yr
CMT is looking for a Engineering Manager to help us change the world. CMT has helped protect over 65 million drivers and prevent over 126,000 crashes worldwide. We build AI to solve some of the most difficult challenges …
Skills: Engineering Management, Backend Systems, Distributed Systems, Event-Driven Architecture, Python
Cambridge, Massachusetts, United States · Hybrid
$146k–$234k/yr
The Role: Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of infrastructure (cloud and on-prem) rationalization and AI-readiness initiatives at Moderna globally. We’re …
Skills: Program Management, Infrastructure Engineering, Cloud Modernization, ITSM, Stakeholder Management
Cambridge, Massachusetts, United States · Hybrid
$83k–$138k/yr
POSITION SUMMARY You will apply strong bioinformatics and cloud engineering practices to develop, operationalize and evolve production bioinformatics pipelines to deliver reliable data products for our Pfizer R&D researc…
Skills: Nextflow, Python, Cloud Engineering, Bioinformatics, CI/CD
Cambridge, Massachusetts, United States · On-site
Role: Applications Scientist Location - Cambridge, Massachusetts Reporting: Global Head of Commercial Position Overview Are you passionate about helping customers solve real-world tribology challenges and excited by the …
Skills: Tribology, Lubrication Science, Experimental Research, Technical Presentations, Business Development
Cambridge, Massachusetts, United States · On-site
Job Summary Nanobiosym is an innovative, high-tech company that is developing novel technologies at the nexus of physics, nanotechnology, and biomedicine. Founded by MIT/Harvard alum and located in Cambridge, Massachuset…
Skills: Network Architecture, Systems Architecture, Virtualization, Firewall Configuration, VPN Management
Cambridge, Massachusetts, United States · On-site
Location: On-site only Type: Full-Time Company Overview We are a dynamic, growing company in the digital health sector, revolutionizing healthcare through innovative technology. As we expand our digital presence, we're s…
Skills: Full-Stack Web Development, React, Node.js, Python, Django
Cambridge, Massachusetts, United States · On-site
Location: Cambridge, MA Company: Nanobiosym Job Summary Nanobiosym is an award-winning company at the forefront of nanotechnology, physics, and biomedicine. Based in Cambridge, MA and founded by an MIT/Harvard alum, we a…
Skills: Cybersecurity Architecture, Network Design, Virtualization, Cloud Security, Zero Trust Architecture
Cambridge, Massachusetts, United States · On-site
Job Title: Sr. Embedded Firmware Engineer (Rust and C) Position Overview: We are seeking an experienced Sr. embedded firmware engineer with a strong background in Rust to help re-design and port existing firmware into Ru…
Skills: Rust, C, ARM Cortex-M, Bare-metal programming, Firmware architecture
Cambridge, Massachusetts, United States · On-site
Nanobiosym is an innovative, high-tech company that is developing novel technologies at the nexus of physics, nanotechnology, and biomedicine. Founded by MIT/Harvard alum and located in Cambridge, Massachusetts, Nanobios…
Skills: HTML, CSS, JavaScript, Vue, React
Cambridge, Massachusetts, United States · Hybrid
$90k–$130k/yr
The trip of a lifetime starts before the airport. For the young adults who travel with EF Ultimate Break, it often starts online, the moment they decide to see the world with a group of people they've never met. As a Pro…
Skills: Product Management, Data Analysis, AI Tool Integration, Direct Code Contribution, A/B Testing
Cambridge, Massachusetts, United States · Hybrid
$286k–$457k/yr
POS-31344 Principal Machine Learning Engineer HubSpot is an all-in-one marketing, sales, and service software platform that helps businesses grow and succeed. With a user-friendly interface and powerful tools, HubSpot en…
Skills: Deep Learning, Large Language Models, PyTorch, TensorFlow, Scikit-learn
Cambridge, Massachusetts, United States · On-site
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Chiller Operation, HVAC Maintenance, Water Treatment Systems, Compressed Air Systems, Troubleshooting
Cambridge, Massachusetts, United States · On-site
Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise…
Skills: Chiller Operation, HVAC Maintenance, Water Treatment Systems, Compressed Air Systems, Troubleshooting
Cambridge, Massachusetts, United States · On-site
$117k–$158k/yr
Overview: The Scientist, Analytical Sciences will be a key team member of the Impurity Characterization team contributing to development and implementation of new strategic analytical technologies. A strong candidate wil…
Skills: Liquid chromatography, Mass spectrometry, Impurity characterization, siRNA therapeutics, HPLC
Cambridge, Massachusetts, United States · On-site
$117k–$158k/yr
Overview: The Scientist, Analytical Sciences will be a key team member of the Impurity Characterization team contributing to development and implementation of new strategic analytical technologies. A strong candidate wil…
Skills: UHPLC, High Resolution Mass Spectrometry, Oligonucleotide Analysis, Impurity Characterization, Design Of Experiments
Cambridge, Massachusetts, United States · Remote OK
$139k–$251k/yr
Do you love building the foundational capabilities that power cloud computing? Are you looking to bridge the gap between deep technical architecture and product strategy? Come join our Cloud Technology Group! This team w…
Skills: Product Strategy, Technical Infrastructure, Software Platform Management, Business Analysis, Financial Modeling
Cambridge, Massachusetts, United States · Hybrid
$160k–$298k/yr
Job Description Summary Location: Cambridge USA; #LI-Hybrid 3 days/week in office Internal job title: Forward Deployed Engineer (FDE) Data42 About the Role: The Forward Deployed Engineer (FDE) at Data42 is an embedded te…
Skills: Palantir Foundry, Data Engineering, Python, Sql, Machine Learning
Cambridge, Massachusetts, United States · On-site
$97k–$161k/yr
Business Introduction At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicin…
Skills: Oligonucleotide Synthesis, Laboratory Automation, SPOS, LC/HRMS, UPHLC
Cambridge, Massachusetts, United States • On-site
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Design and execute in-vitro ADME assays to support drug discovery and compound optimization. Develop next-generation lab automation and AI-enabled analytics to enhance laboratory capacity and data quality.
Requires a BSc or MSc in drug metabolism, pharmacokinetics, or a related field with 4 to 7+ years of experience. Proficiency in metabolic stability, permeability assays, and bio-analytical techniques like LCMS-MS is highly preferred.
Plan, execute and report ADME assays such as metabolic stability and permeability to support PK Science’s strategies.
Interpret in vitro ADME data and translate findings to support early discovery, compound optimization and selection.
Contribute to novel ADME methodologies and expand assay capabilities.
Advance automation strategies (e.g., liquid handling, assay miniaturization, assay multiplexing) to expand laboratory capacity, standardize execution to reduce manual effort, and strengthen discovery assay operations.
Execute and/or contribute to fully automated, end-to-end ADME assay workflows integrated with AI-enabled analytics.
Develop methods to support small and large molecule bio-analysis using LCMS-MS, HRMS, and ICP-MS techniques.
Troubleshot lab instrumentation and automation platforms.
Manage study timelines, objectives and budgets, ensure accuracy of project progress in company tracking tools.
Under management supervision, work to effectively communicate data, strategy and results to the project teams.
Contribute to internal ADME study reports and regulatory documents (IND, IMPD, NDA, etc.).
Participate in cross-departmental teams, department-wide initiatives and work streams.
Complete all required organizational trainings and requirements according to corporate timelines.
Adhere in strict accord to the appropriate SOP, quality and HSE guidelines.
BSc or MSc with relevant experience in drug metabolism and pharmacokinetics or related field.
BSc: 7+ years; MSc: 4+ years of ADME/DMPK experience.
Experience working in a drug discovery or development laboratory or relevant experience in a CRO, Pharma or Biotech is highly desirable.
Experience in metabolic stability and permeability assays highly preferrable; cell culture experience is a plus.
Experience with laboratory automation integrated with AI-enabled analytics is highly desirable.
Knowledge of related disciplines (e.g., bioanalytical, toxicology, biomarker) in the drug discovery or development process.
Ability to work as part of a cross-functional team in a highly dynamic, matrixed, project-team environment.
Strong organizational and project skills with critical thinking and problem-solving skills.
Fluent oral and written English
The salary for this position is expected to range between $89,600 and $166,400 per year.
The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. To learn more about the culture, rewards and benefits we offer our people click here.
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
https://www.novartis.com/careers/careers-research/notice-all-applicants-us-job-openings
Novartis is an innovative medicines company. Every day, working to reimagine medicine to improve and extend people’s lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 250 million people worldwide. Find out more at https://www.novartis.com See our community guidelines: https://go.novartis.social/3Nboxki
Offices: Novartis Campus, Basel, Baselstadt 4002, CH · One Health Plaza, East Hanover, NJ 07936, US · Calle 93B S-31, Bogota, Bogota, D.C. 110541, CO · Merrion Road, Dublin, County Dublin, IE · Na Pankraci 1724/129, Prague, Prague 140 00, CZ
Based on 627 listings with disclosed salaries, most engineering jobs in Cambridge, MA pay between $82k–$240k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 786 open engineering positions in Cambridge, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Draper, Akamai Technologies, Lila Sciences, Flagship Pioneering, Novartis, among others. Browse the listings above to see every active employer.
Yes — 237 of the 786 open engineering positions offer remote or hybrid work (65 remote, 172 hybrid).
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