Bedford, Massachusetts, United States · Remote OK
$225k–$250k/yr
About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augment…
Skills: CMC Leadership, Process Development, Analytical Methods, Tech Transfer, CMC Regulatory Strategy
Bedford, Massachusetts, United States · Remote OK
$140k–$161k/yr
About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augment…
Skills: Process Validation, Drug Substance Manufacturing, Drug Product Manufacturing, CMO Management, GMP Compliance
Bedford, Massachusetts, United States · On-site
Overview Senior Test Engineer LOCATION: Hanscom AFB, MA SALARY RANGE: $135-$145,000 annually* *depending on experience, certifications, and qualifications JOB STATUS: Full-time CLEARANCE: Secret TRAVEL: Limited, as neede…
Skills: Test and Evaluation, Agile Methodologies, DevSecOps, CI/CD Pipelines, DoD Testing Regulations
Bedford, Massachusetts, United States · On-site
$120k–$130k/yr
Applied Research Solutions is seeking a Senior Configuration Manager to provide support to the Air Force Life Cycle Management Center - Ground Base Air Defense Sensor Division (AFLCMC/ESG). The ESG Division manages effor…
Skills: Configuration Identification, Change Control, Status Accounting, Configuration Control Board Support, Physical Configuration Audit
Bedford, Massachusetts, United States · Hybrid
$100k–$135k/yr
Job Title: Senior Engineer, Applications & Design Engineer Job Description: The Role Entegris is currently seeking an Applications & Design Engineer to join our Specialty Coatings Group team, based in our Bedford, MA fac…
Skills: SolidWorks, Mechanical Design, Vacuum Technology, Applications Engineering, Process Optimization
Bedford, Massachusetts, United States · On-site
Overview Principal Data Links and Communications Engineer LOCATION: Hanscom AFB, MA Salary Range: $145-$155,000 annually* *depending on experience, certifications, and qualifications JOB STATUS: Full-time CLEARANCE: Top …
Skills: Link 22, Tactical Data Links, C++, Java, MBSE
Bedford, Massachusetts, United States · On-site
Overview Principal Data Links and Communications Engineer LOCATION: Hanscom AFB, MA Salary Range: $145-$155,000 annually* *depending on experience, certifications, and qualifications JOB STATUS: Full-time CLEARANCE: Top …
Skills: Link 22, Tactical Data Links Engineering, C++, Java, MBSE
Bedford, Massachusetts, United States · On-site
$140k–$150k/yr
Applied Research Solutions (ARS) is seeking a Senior Configuration and Data Manager (CM/DM) to support the Nuclear Command, Control, and Communications (NC3) Contract within the NCN Division, supporting the GASNITi1 and …
Skills: Configuration Management, Data Management, Quality Assurance, Software Engineering, Configuration Control Board Support
Bedford, Massachusetts, United States · On-site
Overview Senior Program Manager WORK LOCATION:Hanscom AFB, MA Salary Range:$120,000-$130,000* *depending on experience, certifications, and qualifications JOB STATUS: Full-time; Salaried Clearance: Secret clearance requi…
Skills: Program Management, DoD Acquisition Strategy, Strategic Planning, Leadership, RFP Documentation
Bedford, Massachusetts, United States · On-site
$70k–$90k/yr
We are NOT accepting resumes from recruitment agencies or search firms. About Instylla: Instylla, Inc. is a privately held medical device company based in Bedford, MA, focused on developing novel resorbable embolic agent…
Skills: Process Validation, IQ/OQ/PQ, Supplier Change Management, Sustaining Engineering, Good Manufacturing Practices
Bedford, Massachusetts, United States · On-site
$92k–$167k/yr
Position Summary: The Leidos Airborne & Mission Solutions Business Area is seeking an experienced Acquisition Program Support professional to serve as the Site Lead supporting Hybrid SATCOM acquisition and program manage…
Skills: Acquisition Program Support, Program Management, SATCOM, Stakeholder Management, Contract Management
Bedford, Massachusetts, United States · On-site
$85k–$127k/yr
Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with…
Skills: Validation Test Strategy, Protocol Authoring, Data Analysis, DOE Studies, Risk Assessment
Bedford, Massachusetts, United States · On-site
$85k–$178k/yr
Work Location: Bedford, Massachusetts Shift: No Department: LS-PS-IC Single Use Core Recruiter: Stefanie Fried This information is for internals only. Please do not share outside of the organization. Your Role: Join us a…
Skills: Product Management, Strategic Marketing, Bioprocessing, Single-Use Assemblies, Market Analysis
Bedford, Massachusetts, United States · On-site
$130k–$160k/yr
ARS is seeking a Senior Application Software Developer to support Hanscom, AFB. Why Work with Us? Applied Research Solutions (ARS) is a respected, world-class provider of technically integrated solutions. We deliver prem…
Skills: BMC Product Integration, Application Customization, Remedy Foundation Data, ITIL, Technical Documentation
Bedford, Massachusetts, United States · On-site
$148k–$164k/yr
Applied Research Solutions is seeking a full-time cybersecurity professional located at Hanscom, AFB. Why Work with us? Applied Research Solutions (ARS) is respected as a world-class provider of technically integrated so…
Skills: Risk Management Framework, Authorization and Accreditation, Vulnerability Assessment, Systems Security Evaluation, Disaster Recovery Planning
Bedford, Massachusetts, United States · On-site
$150k–$165k/yr
Applied Research Solutions is seeking a Cybersecurity Engineer Journeyman located Hanscom AFB. Why Work with us? Applied Research Solutions (ARS) is respected as a world-class provider of technically integrated solutions…
Skills: RMF Authorization And Accreditation, Cybersecurity Engineering, Vulnerability Remediation, Risk Assessment, System Security Management
Bedford, Massachusetts, United States · On-site
$45/hr–$55/hr
Description This role will be responsible for ensuring the new catheter and console products and design changes to existing products meet regulatory and quality requirements throughout the design, development, and manufa…
Skills: Design Controls, Risk Management, Verification and Validation, Root Cause Analysis, CAPA
Bedford, Massachusetts, United States · On-site
$19/hr–$24/hr
Introduction Werfen Werfen is a growing, family-owned, innovative company founded in 1966 in Barcelona, Spain. We are a worldwide leader in specialized diagnostics in the areas of Hemostasis, Acute Care Diagnostics, Tran…
Skills: Troubleshooting, Corrective Action, Cycle Counting, 5S Methodology, Technical Documentation
Bedford, Massachusetts, United States · On-site
Overview: The Electronic Technician will perform electrical/mechanical assembly and testing of electrical systems and associated components. In addition to standard construction, the Electronic Technician will also be re…
Skills: Electrical Assembly, Mechanical Assembly, Diagnostic Testing, Troubleshooting, Soldering
Bedford, Massachusetts, United States · On-site
$160k–$180k/yr
Overview Abacus Technology is seeking a Logistics Manager to provide acquisition support for the Technical Advisory and Assistance Services (TAAS) program at Hanscom AFB. This is a full-time position. Responsibilities Di…
Skills: Logistics Management, Acquisition Support, DoD 5000, Product Support Planning, Integrated Product Support
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Lead cross-functional teams accountable for Chemistry, Manufacturing, and Controls (CMC) product lifecycle management from early development through commercial launch. Serve as the primary CMC voice in program governance, overseeing supply strategies, regulatory filings, and drug-device compatibility.
Requires a Bachelor's degree in a scientific field (advanced degree preferred) and 10+ years of industry experience in CMC development. Must have significant experience with drug-device combination products and a proven track record of leading late-stage development through commercial launch.
Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke’s initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke’s proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/
The Stoke Therapeutics team is seeking an experienced and driven Director, CMC Lead to lead cross-functional teams that are accountable for chemistry, manufacturing, and controls (CMC) product lifecycle management. This individual will serve as the single point of accountability for all CMC activities, from early development through regulatory approval and commercial lifecycle management. This individual will play a central role in shaping the technical and operational direction of their assigned programs. The CMC Lead role is a highly visible matrix team leader that provides strategic and technical leadership within CMC, while representing CMC on cross-functional Program Teams.
The ideal candidate will possess strong knowledge of CMC leadership with deep understanding of process development, analytical methods, tech transfer, manufacturing, CMC regulatory strategy and health authority interactions. Additionally, this individual should possess strong interpersonal communication skills, high emotional intelligence, and be fluent in the art of negotiation.
This position will report into the Vice President, Commercial Manufacturing.
Stoke is located in Bedford, MA, and will be moving to a new location in Waltham, MA by the end of 2026. This position is eligible for either remote or hybrid work arrangements.
This position will require approximately 10-20% travel.
At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program.
The anticipated salary range for this role is $225,000 - $250,000 The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation.
Our benefits package includes medical, dental and vision insurance; life, long- and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP).
At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation.
Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do.
https://www.stoketherapeutics.com/careers/
For more information, visit https://www.stoketherapeutics.com/.
All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status.
Stoke participates in E-Verify.
Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke’s initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke’s proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit https://www.stoketherapeutics.com/.
Offices: 45 Wiggins Ave, Bedford, Massachusetts 01730, US
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