Basel, Basel-City, Switzerland · Hybrid
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress dive…
Skills: Pharmacovigilance, Signal Detection, Risk Management, Aggregate Reporting, Benefit-Risk Assessment
Universitätsbibliothek BaselBasel, Basel-City, Switzerland · On-site
(100%, start date upon agreement) Shape the future of quantum computing! As a Postdoctoral Fellow in our team, you will develop ultrafast, non-destructive spin qubit readout—a critical milestone for scalable quantum proc…
Skills: Condensed matter physics, Quantum dot systems, Superconducting circuits, High-frequency transport experiments, Cryogenic measurements
Basel, Basel-City, Switzerland · Hybrid
$221k–$410k/yr
Salary Range: CHF220,500.00 - CHF409,500.00 Band Level 8 Job Description Summary #LI-Hybrid Location: Basel, Switzerland What if the deals you shape today could define the future of healthcare? As Head BD&L Transactions,…
Skills: Business Development, Licensing, Deal Structuring, Contract Negotiation, Investment Banking
Basel, Basel-City, Switzerland · Hybrid
$221k–$410k/yr
Salary Range: CHF220,500.00 - CHF409,500.00 Job Description Summary #LI-Hybrid Location: Basel, Switzerland What if the deals you shape today could define the future of healthcare? As Head BD&L Transactions, Immunology, …
Skills: Business Development, Licensing, Deal Structuring, Contract Negotiation, Strategic Planning
Basel, Basel-City, Switzerland · On-site
Salary Range: CHF 0.00 - CHF 0.00 Job Description Summary This postdoctoral fellowship offers a unique opportunity to advance the use of artificial intelligence and machine learning for chemical synthesis and reactivity …
Skills: Machine Learning, Deep Learning, Python, Graph Neural Networks, Transformer Architectures
Basel, Basel-City, Switzerland · On-site
Salary Range: CHF 0.00 - CHF 0.00 Job Description Summary We are excited to invite applications for the Novartis Biomedical Research Postdoctoral Fellowship Program, a unique training opportunity designed for exceptional…
Skills: Human Organoid Models, Cellular Biology, Molecular Biology, CRISPR-Cas9, Immunology
Basel, Basel-City, Switzerland · On-site
Salary Range: CHF 0.00 - CHF 0.00 Job Description Summary The AI Innovation Postdoctoral Fellow will develop cutting-edge machine learning and generative AI methods for treatment effect modeling, patient stratification, …
Skills: Machine Learning, Generative AI, Causal Inference, Treatment Effect Modeling, Patient Stratification
Basel, Basel-City, Switzerland · On-site
Salary Range: CHF 0.00 - CHF 0.00 Job Description Summary The Novartis Biomedical Research Postdoctoral Fellowship Program offers a 3-year 100% position starting October 1, 2026, in Basel, Switzerland, focusing on founda…
Skills: Cheminformatics, Machine Learning, Deep Learning, Python, Linux HPC
Basel, Basel-City, Switzerland · On-site
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who …
Skills: siRNA Design, RNAi Mechanism, Chemical Modification Patterns, Bioinformatics, Biological Sequence Analysis
Basel, Basel-City, Switzerland · On-site
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who …
Skills: Solid-State Characterization, Crystallization, XRD, DSC, TGA
Basel, Basel-City, Switzerland · On-site
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who …
Skills: Oral Enabling Formulation Technologies, Lipid Based Delivery Systems, Amorphous Solid Dispersion, Spray-Drying, Hot-Melt Extrusion
Basel, Basel-City, Switzerland · On-site
The actual location of this job is in Basel Stücki, Switzerland. This is a fully site‑based role. Working together in person supports close, real‑time collaboration and the technical precision needed to manufacture medic…
Skills: Light Microscopy, FTIR Spectroscopy, Raman Spectroscopy, Analytical Studies, Pharmaceutical R&D
Basel, Basel-City, Switzerland · On-site
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who …
Skills: Toxicologic Pathology, Computational Pathology, Python, Image Analysis, Machine Learning
Basel, Basel-City, Switzerland · On-site
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who …
Skills: Hematology, Safety Biomarkers, Translational Safety Assessment, In Vitro Assays, Ex Vivo Assays
Basel, Basel-City, Switzerland · On-site
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who …
Skills: Immunotoxicology, In Vitro Modeling, In Vivo Immunosafety, Flow Cytometry, High-Content Screening
Basel, Basel-City, Switzerland · Hybrid
$123k–$228k/yr
Salary Range: CHF122,500.00 - CHF227,500.00 Band Level 5 Job Description Summary As a Solution Architect in Innovation & Delivery, you are responsible for not only designing and planning, but actively guiding thru execut…
Skills: Solution Architecture, Innovation Strategy, Biomedical Research, AI Solutions, Data Platforms
Basel, Basel-City, Switzerland · Hybrid
$160k–$296k/yr
Salary Range: CHF159,600.00 - CHF296,400.00 Band Level 6 Job Description Summary #LI-Hybrid Location: Basel, Switzerland Step into a pivotal role where your leadership can directly shape how breakthrough cardiovascular i…
Skills: Market Access Strategies, Health Economics, Health Technology Assessment (HTA), Pricing Strategies, Cross-Functional Collaboration
Basel, Basel-City, Switzerland · Hybrid
$160k–$296k/yr
Salary Range: CHF159,600.00 - CHF296,400.00 Job Description Summary #LI-Hybrid Location: Basel, Switzerland Step into a pivotal role where your leadership can directly shape how breakthrough cardiovascular innovations re…
Skills: Market Access Strategies, Health Economics, Health Technology Assessment (HTA), Pricing Strategies, Cross-Functional Collaboration
Basel, Basel-City, Switzerland · Hybrid
$123k–$228k/yr
Salary Range: CHF122,500.00 - CHF227,500.00 Job Description Summary As a Solution Architect in Innovation & Delivery, you are responsible for not only designing and planning, but actively guiding thru execution end-to-en…
Skills: Solution Design, Innovation Strategy, Biomedical Research, AI Strategy, Data Platforms
Basel, Basel-City, Switzerland · Hybrid
$94k–$174k/yr
Salary Range: CHF93,800.00 - CHF174,200.00 Job Description Summary The Innovation Scout drives early identification and translation of emerging technologies, scientific opportunities, and external innovations into action…
Skills: Innovation Scouting, Rapid Prototyping, Strategic Thinking, Life Sciences Domain Knowledge, AI Technology Landscape
Basel, Basel-City, Switzerland • Hybrid
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Lead the design and maintenance of Global Patient Safety processes, including signal detection, risk management, and aggregate reporting. Provide expert consultation for regulatory filings and ensure global inspection readiness and compliance with PV regulations.
Requires an advanced degree in Medicine, Pharmacy, or a related field with at least 10 years of experience in pharmacovigilance within the biotech or pharma industry. Must possess in-depth knowledge of global PV regulations (ICH, GxP) and a proven track record of leadership.
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Principal Scientist of Safety Surveillance is a member of the Surveillance team serving as a lead principal subject matter expert for the design, development, maintenance, and support of core Global Patient Safety (GPS) processes. This individual will lead and/or contribute to safety development activities including scientific innovation and enablement across various disciplines relevant to clinical safety and pharmacovigilance, such as but not limited to safety risk management, signal detection & management, comparative benefit-risk, and aggregate reporting. The Principal Scientist of Safety Surveillance supports Revolution Medicines to continuously deliver effective scientific safety activities and/or pharmacovigilance (PV) activities, in line with health authority and internal stakeholder requirements. The Principal Scientist of Safety Surveillance will have robust and highly experienced understanding of the internal and external operating environment, which will enable anticipation of new developments and implementation of improvements critical to process maintenance and refinement at Revolution Medicines.
Responsibilities include:
Serve as the lead principal subject matter expert for the design, development, maintenance, and support of one or more core GPS processes (i.e. comparative benefit-risk, signal detection & management, risk management, aggregate reporting, etc.) in compliance with applicable Good Clinical Practice (GCP), Good Pharmacovigilance Practice (GVP), Good Documentation Practices (GDocP), etc., in alignment with the company’s mission and objectives.
Manage the assigned core safety process(es) and support the execution/delivery of the required outputs (e.g. Risk Management Plans (RMPs), Developmental Safety Update Reports (DSURs), Periodic Safety Update Reports (PSURs), etc.) in compliance with global regulatory requirements and following best practices.
Provide expert consultation and direction for Development and filing teams where impactful as it relates to PV portions of regulatory reports and clinical study documents (including Clinical Protocols, Informed Consent Forms, Investigator Brochures, NDA filing packages (i.e. Module 2: Clinical Overview, Clinical Summary, Integrated Summary of Safety (ISS), Integrated Summary of Efficacy (ISE), safety narratives), and labeling strategy.
Lead the development of controlled documentation required to demonstrate control and oversight of the PV aggregate reporting process and other processes as needed.
Work with the EU Qualified Person Responsible for Pharmacovigilance (QPPV) to ensure European compliance as applicable.
Contribute to the development and maintenance of a PV quality system in line with global regulations (i.e. GCP, GVP) enabling demonstration of quality, effectiveness, and control.
Ensure inspection readiness for global inspections by ensuring processes and training reflect global regulatory requirements as applicable. Act as subject matter expert (SME) for audit and inspection for the assigned process(es).
Drive development of controlled documentation for GPS owned processes as applicable and ensure that Safety’s voice is heard in cross-functional settings.
Strategically influence, implement, improve, and innovate through the development of proposals that advance safety capabilities in line with the GPS mission, vision, goals, and long-term strategy.
Create and implement bespoke solutions that enable GPS stakeholders to provide high-quality safety outputs that address emerging challenges in the healthcare practice setting against a dynamic regulatory landscape.
Work in close partnership with cross-functional stakeholders and anticipate strategic requirements with respect to the assigned process(es).
Maintain expert knowledge of key regulatory/legislative changes and trends in the evolving healthcare setting to anticipate future requirements and apply best practices in the assigned SME area(s).
Translate/expand new and established safety approaches across the RevMed portfolio to enable consistent and high-quality safety surveillance.
Identify, share, and promote good practice innovation to enable continuous process improvement.
Build relationships and collaborative partnerships for GPS and its cross-functional partners both internally and externally (i.e. with development partners).
Collaboration and close interface with internal policy governance bodies in adapting core processes in line with business needs and external requirements.
Ensure clear and effective communication of safety information to internal and external stakeholders.
Partner with PV systems personnel in the development and implementation of fit for purpose PV systems.
Advanced degree in Medicine, Pharmacy, or a related field (MD, PharmD, PhD/MSc, or other post-graduate health professional qualification).
Minimum of 10 years of experience in PV or related field within the pharmaceutical or biotechnology industry.
Proven track record of leadership in PV.
In-depth knowledge of global PV regulations and guidelines (i.e. ICH, GxP) and a record of compliance with these standards.
Strong analytical and strategic thinking, problem-solving, and decision-making skills.
Excellent communication, collaboration, and team management abilities, enabling exertion of strong and successful influence of senior executives as well as strong external representation for the company.
Technical expertise in PV.
Outstanding emotional intelligence.
Experience with advanced safety data analytics and PV systems.
Demonstrated ability to manage complex projects and work effectively in a matrixed organization.
Proficiency in managing regulatory interactions.
Strong organizational and time management skills, with the ability to prioritize and manage multiple tasks effectively.
Excellent influence and collaboration/teamwork capabilities.
BLA/MAA experience.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].
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We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to [email protected] so we can share these impersonations with our IT team for tracking and awareness.
Revolution Medicine enables physicians to integrate personalized medicine into their practices in order to more effectively treat patients. Our genes play an important role in determining how we respond to about 75% of prescription drugs. Scientific research has demonstrated which genes predict these responses. According to the American Medical Association (AMA), 98% of physicians agree that knowing a patient’s genetic profile would help in prescribing medications. Yet, 90% of physicians do not feel they are adequately informed about how to apply genetic testing to treatment decisions. Our mission is to improve the quality of patient care by helping doctors determine optimal treatment strategies and more accurately predict treatment responses. Revolution Medicine has developed ScriptMatch, an analytical process that enables physicians to easily incorporate genetic testing into their practices. Our company solves a major issue in the clinical market and addresses an emerging trend in patient-driven healthcare: having clinical results that become part of the medical record and applicable to future treatments.
View all jobs at Revolution MedicineThere are currently 262 open science & research positions in Basel, Switzerland listed on Clera. New openings are added daily as companies post roles.
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