Sr Scientist I, Discovery Biotherapeutics – Multispecifics Engineering
Worcester, Massachusetts, United States · On-site
$97k–$184k/yr
Senior
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Technician, Manufacturing III (Sunday to Wednesday, 6:00am - 4:30pm)
Worcester, Massachusetts, United States · On-site
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Principal Research Scientist I, In Vivo Antibody Discovery
Worcester, Massachusetts, United States · On-site
$125k–$237k/yr
Senior+
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Sr Scientist I, Discovery Biotherapeutics – Multispecifics Engineering
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$97k–$184k/yr
Full-time
postgraduate degree
Paid time off, Medical insurance, Dental insurance, Vision insurance, 401(k), Short-term incentive programs
Posted 12d ago
~40 hrs/week
Responsibilities
The scientist will lead the design, engineering, and production of multispecific biopharmaceutical products to support oncology therapeutic projects. They will also serve as a technical representative for cross-functional teams and implement innovative process research solutions.
Requirements
Candidates must hold a PhD or MS degree in Biochemistry, Biochemical engineering, or a related discipline with relevant experience in biologics and multispecifics. Strong molecular biology skills and proficiency in protein characterization techniques are essential for this role.
Full job description
Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn,Facebook, Instagram, X and YouTube.
Job Description
Purpose
Discovery Biotherapeutics at AbbVie is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting design, engineering, and production of multispecifics. This position will impact projects through engineering, production, and characterization of multispecific biopharmaceutical products. The ideal candidate should have experience with biologics and multispecifics production platforms, analytical characterization. It is preferred that the candidate would have experience with ADCs and/or Oncology focused multispecifics. The applicant should be an enthusiastic, creative scientist who will make tangible contributions to the continuous improvement and innovation within the organization.
Key responsibilities:
Responsible for design, engineering and production of multispecific biologics to support the Oncology therapeutic area.
Evaluate and integrate state-of-the-art technology to improve therapeutic production platforms, and demonstrate creative “out-of-the-box” thinking to solve difficult problems
Serve as a Multispecifics Engineering representative for cross-functional teams, and contribute scientific insights into multiple projects across various therapeutic areas; recognized expert in multispecifics design and production
Identify and solve technical problems independently, conceive and implement innovative process research ideas
Ensure consistency and quality of technical reports
Provide project update, analysis and advice to cross-functional teams and senior management
Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents
Qualifications
Qualifications
PhD or MS degree in Biochemistry, Biochemical engineering or related disciplines
Title to be determined by years of experience, ideally in multispecifics biologics engineering:
Sr Sci I 0-4 (PhD), 6+ (MS), or 8+ (BS)
Experience with protein, biologics, fragments, and multi-specifics design, expression and purification
ADC and multispecific ADC design experience preferred
Strong molecular biology skills (e.g. molecular cloning) and experience with sequence analysis tools (Vector NTI, Geneious, Genedata)
Experience with purification and automation instruments (e.g. Akta, Kingfisher, Hamilton)
Experience with in vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF)
Experience with developability screening for multispecifics preferred
Experience with CRO coordination preferred
Excellent organizational skills and the ability to manage multiple projects simultaneously and adapt to rapid change in priorities
Candidate must be a goal-oriented team player with excellent verbal and written communication skills, ability to operate in a fast-paced multi-disciplinary environment, and strong can-do attitude
Recognized in the scientific community through a sustained record of peer-reviewed publications and patents preferred
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
Allergan is now part of AbbVie.
AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio.
For more information about AbbVie, please visit us at www.abbvie.com. Follow @AbbVie on LinkedIn for future updates.
Offices: Allergan plc, Dublin, Coolock D17 E400, IE · Morris Corporate Center III, 400 Interpace Parkway, Parsippany, NJ 07054, US · Parkway, Marlow, England SL7 1YL, GB · 301 W Howard Ln, Austin, TX 78753, US · 8301 Mars Dr, Hewitt, TX 76712, US
Health CareBiopharmaEducationBiotechnologyMedicalUniversitiesPharmaceutical
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