Boston, Massachusetts, United States · Hybrid
$212k–$333k/yr
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice an…
Skills: Medicinal Chemistry, SAR Intuition, AI/ML Design Tools, Lead Optimization, Candidate Nomination
Boston, Massachusetts, United States · On-site
$150k–$195k/yr
At WHOOP, we’re on a mission to unlock human performance. WHOOP empowers members to perform at a higher level through a deeper understanding of their bodies and daily lives. WHOOP is seeking a Senior Technical Program Ma…
Skills: Technical Program Management, NPI Execution, Hardware Development, Manufacturing Process Development, Risk Management
Boston, Massachusetts, United States · On-site
$150k–$210k/yr
WHOOP is an advanced health and fitness wearable, on a mission to unlock human performance. WHOOP empowers its members to improve their health and perform at a higher level by providing a deep understanding of their bodi…
Skills: Python, Machine Learning Systems, System Design, Backend Development, Cloud Infrastructure
Hartford, Connecticut, United States · Hybrid
$192k–$240k/yr
Together we fight for everyone’s opportunity for a better financial future. We will do this together — with customers, partners and colleagues. We will fight for others, not against: We will stand up for and champion eve…
Skills: AI System Design, LLM Application Development, MLOps, Model Evaluation, Python
Boston, Massachusetts, United States · On-site
Job Requirements The Building Automation Technician (Integration Specialist) IV serves as an advanced-level technical expert responsible for leading the integration of advanced building automation system (BAS) projects. …
Skills: Building Automation Systems, HVAC, Control Theory, BACnet, LON
Boston, Massachusetts, United States · On-site
$105k–$145k/yr
At WHOOP, we're on a mission to unlock human performance and healthspan. WHOOP empowers users to perform at a higher level through a deeper understanding of their bodies and daily lives. Our wearable device tracks key ph…
Skills: Kotlin, Java, Android Jetpack, MVVM, MVI
Boston, Massachusetts, United States · Remote OK
$43/hr–$53/hr
Job Summary The Technical Support Engineer for Clinical AI product line is the first point of contact for users, providing expert support, troubleshooting issues, and contributing to a seamless healthcare IT experience. …
Skills: Technical Support, Windows Server, Linux Administration, MSSQL, Networking
Boston, Massachusetts, United States · On-site
$130k–$185k/yr
At WHOOP, we're on a mission to unlock human performance and health span. WHOOP empowers members to perform at a higher level through a deeper understanding of their bodies and daily lives. By delivering actionable insig…
Skills: Mechanical Design, SolidWorks, Prototyping, DFx, Design of Experiments
Boston, Massachusetts, United States · On-site
$130k–$185k/yr
At WHOOP, we're on a mission to unlock human performance and healthspan. WHOOP empowers members to perform at a higher level through a deeper understanding of their bodies and daily lives. As an Electrical Test Tech Lead…
Skills: Electrical Engineering, System Validation, Python, Git, Test Automation
Boston, Massachusetts, United States · On-site
$45/hr–$65/hr
Overview Monte Rosa Therapeutics is seeking a passionate Senior Research Associate with the experience to implement and run biochemical and biophysical characterization assays. This is an exciting opportunity to join a t…
Skills: Biochemical Assays, Biophysical Characterization, TR-FRET, Fluorescence Polarization, Differential Scanning Fluorimetry
Boston, Massachusetts, United States · On-site
$33/hr–$38/hr
Job TitleMaintenance Mechanic- 2nd Shift Job Description SummaryC&W Services is searching for a maintenance mechanic to staff one of its customers landmark properties. In addition, this a union location with great wages,…
Skills: HVAC Maintenance, Electrical Systems, Plumbing, Building Automation Systems, Preventative Maintenance
Boston, Massachusetts, United States · On-site
$150k–$215k/yr
At WHOOP, we’re on a mission to unlock human performance and healthspan. WHOOP empowers members to perform at a higher level through a deeper understanding of their bodies and daily lives. WHOOP is hiring a Senior Engine…
Skills: Technical Program Management, Algorithm Development, Cross-functional Leadership, Release Management, Stakeholder Management
Boston, Massachusetts, United States · On-site
About Ayo Ayo is a venture-backed early-stage startup that will radically redefine how humanity performs compute for AI. Our photonic processors will provide orders of magnitude improvement in speed and power efficiency …
Skills: Systems Engineering, Photonic Systems, Integrated Photonics, Integrated Electronics, System-Level Modeling
Boston, Massachusetts, United States · On-site
$135k–$175k/yr
Job Description: Position Description: Note: Fidelity will not provide immigration sponsorship for this position. Conducts research studies and develops quantitative techniques, models and tools to support and enhance th…
Skills: Python, R, MATLAB, SQL, Machine Learning
Boston, Massachusetts, United States · On-site
$42/hr–$67/hr
Job Description The Vertex Cell and Gene Therapy (C>) Quality Control (QC) team is responsible for the routine testing of samples and associated workflows for our internally manufactured stem-cell based T1D and genetic…
Skills: Flow Cytometry, Cell Counting, Cell Culture, Sterility Testing, Endotoxin Testing
Boston, Massachusetts, United States · On-site
Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our missio…
Skills: Medical Equipment Repair, Calibration, Electrical Safety Testing, Troubleshooting, Preventive Maintenance
Boston, Massachusetts, United States · On-site
This position is part of the AWS Specialist and Partner Organization (ASP). Specialists own the end-to-end go-to-market strategy for their respective technology domains, providing the business and technical expertise to …
Skills: Cloud Computing, AI Services, Enterprise Application Architecture, Solution Architecture, Technical Strategy
Boston, Massachusetts, United States · Hybrid
$90k–$124k/yr
Lead impactful hydrogeologic investigations and remediation projects with a global sustainability leader. ERM is seeking a motivated and detail-oriented Managing Consultant, Hydrogeologist to join our growing team in Bos…
Skills: Hydrogeologic Investigation, Remediation Project Management, Conceptual Site Modeling, Field Data Collection, Aquifer Testing
Boston, Massachusetts, United States · On-site
Job Requirements The Integration Specialist V serves as a senior-level technical expert and escalation point for technical issues within the Integration team. This role leads large, multi-system integration projects, sup…
Skills: System Integration, BAS, HVAC, BACnet, LON
Boston, Massachusetts, United States · Remote OK
$80k–$185k/yr
(Remote, ET+/-1 (e.g. Boston, Argentina), Series B DevTools SaaS) Join Checkly as a Customer Solutions Engineer and empower developers and agents to own and ensure application performance and reliability - from pull requ…
Skills: Javascript, Node.js, Technical Consulting, Customer Relationship Management, Debugging
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Lead the design and optimization of drug candidates by integrating AI/ML proposals with deep medicinal chemistry judgment. Provide strategic oversight of CRO synthesis programs to rapidly close DMTA cycles and deliver candidates to the clinic.
Requires a PhD in medicinal or organic chemistry with 12-15+ years of drug discovery experience and a track record in lead optimization. Must possess expertise in SAR-driven design and the ability to critically challenge computational outputs from AI tools.
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.
Takeda Research is constructing the Discovery Automation & Robotics (DAR) group built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost. To catalyze these efforts, Takeda is creating two complementary units: AI Research Accelerator (AIRx) and The Discovery Automation & Robotics (DAR) group.
AIRx will consist of a dedicated group of experienced drug hunters with the autonomy of a biotech and the resources of a leading pharmaceutical company. It is designed to incubate the future AI-powered operating models and deliver candidates to the clinic at industry leading speed and success rates.
Purpose
This is medicinal chemistry as it should be — pure design, at speed, with the best tools available. You will work at the frontier of AI-enabled molecular design: evaluating generative proposals, applying deep SAR judgment, and directing CRO synthesis to close DMTA cycles faster than any traditional discovery team. No synthetic bench. No compound store. Just expert chemistry thinking applied at maximum velocity.
The AIRx Medicinal Chemist is a seasoned drug hunter who thrives in lean, autonomous environments and is excited to work at the frontier of AI-driven drug design. Strong SAR intuition, decisiveness, and the confidence to challenge computational outputs are as important as deep chemistry expertise. We are not looking for someone who will defer to the AI. We are looking for someone who will argue with it, stress-test its proposals against hard-won SAR experience, and make better molecules because of that tension. If you have deep chemistry instinct and genuine curiosity about what generative AI can and cannot do — this is where that combination produces real impact.
Accountabilities
Qualifications & Competencies
The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
U.S. Base Salary Range:
$212,000.00 - $333,190.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Better Health, Brighter Future
We strive to transform lives. While the science we advance is constantly evolving, our core purpose is enduring. For more than two centuries, our values have guided us to do what’s right for patients and for society. We know that changing lives requires us to do things differently. We start by listening to and addressing what really matters to patients, the people who love them, and those in the healthcare system who provide care. And that’s what inspires us all to be bold, push boundaries and set new standards that open up greater opportunities. Read our community guidelines: https://takeda.info/communityguidelines
Offices: Tokyo, JP · 1 Takeda Parkway, Deerfield, Illinois 60015, US · 40 Landsdowne St, Cambridge, Massachusetts 02139, US · Avenida das Nações Unidas, 14.401, Torre Jequitibá - 10°, 11° e 12° andares, São Paulo, 04794-000, BR · 43 Old Oak Rd, Bellville, Western Cape 7550, ZA
Based on 1731 listings with disclosed salaries, most engineering jobs in Boston, MA pay between $90k–$212k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 2,130 open engineering positions in Boston, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include WHOOP, State Street, Amazon, Klaviyo, Mass General Brigham, among others. Browse the listings above to see every active employer.
Yes — 978 of the 2130 open engineering positions offer remote or hybrid work (236 remote, 742 hybrid).
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