SaaS startups in San Francisco

Cognition

San Francisco

The company is an applied AI lab that builds end-to-end software agents and collaborative AI teammates, enabling engineers to focus on more interesting problems and empowering teams to pursue ambitious goals; it markets Devin as the first A

Poolside

San Francisco

Poolside is building the world's most capable AI for software development, focusing on distributed training and inference of large language models for source code generation, with a mission to unlock developers' potential through AI for sof

Decagon

San Francisco

Decagon is a leading conversational AI platform delivering concierge customer experiences with AI agents across chat, email, and voice in any language. It serves brands like Hertz, Eventbrite, Duolingo, and Oura and is backed by Accel and A

LMArena

San Francisco

LMArena, created by UC Berkeley researchers, is an open platform for accessing and comparing leading AI models, where users rate responses and help build a public, real-world leaderboard to increase transparency in AI progress.

Assort Health

San Francisco

Assort Health offers what it calls the most comprehensive patient experience platform, handling 115M+ interactions since 2023 with 98%+ resolution, 99% scheduling accuracy, 4.4/5 patient satisfaction, and 15x revenue growth since Q4 2024, l

Cartesia

San Francisco

Cartesia builds the next generation of AI—ubiquitous, interactive intelligence that runs wherever you are. It maintains a Discord community (discord.com/invite/cartesia) and showcases its work at cartesia.ai.

Serval

San Francisco

Serval is an AI platform for IT teams that replaces legacy systems with automation, freeing people to focus on meaningful work. It is trusted by Perplexity, Together AI, Writer, Mercor, and Verkada to automate over half of their IT tickets.

DepthFirst

San Francisco

depthfirst is an applied AI lab dedicated to securing the world's software, focusing on AI-native security as software underpins modern civilization and exploits are expected to rise with AI proliferation.

Campfire

San Francisco

Campfire is an AI-native ERP for mid-size and enterprise companies to close fast and scale faster. Based in San Francisco, it is backed by Accel, Foundation Capital, Y Combinator and Capital49(Airwallex), serving 50 to 5,000-employee firms

Listen Labs

San Francisco

Listen is an autonomous market researcher that uses AI to design interviews, recruit participants, and analyze responses, delivering insights in hours rather than weeks, 24/7. Trusted by Google, Microsoft, SKIMS, Nestlé, and hundreds of ent

Bretton AI

San Francisco

Bretton AI (formerly Greenlite AI) builds AI agents for financial crime compliance, helping banks and fintechs automate AML and KYC work.

David AI

San Francisco

David AI builds audio datasets through R&D; founded in 2024 by former Scale AI engineers, it counts FAANGs and AI labs among customers and raised a $50M Series B from Meritech, NVIDIA and others, achieving seven-figure revenue in six months

Edison Scientific

San Francisco

Edison Scientific, spun out from FutureHouse in 2025, accelerates scientific discovery by building and commercializing AI agents for science, pursuing an AI Scientist to scale autonomous research and tackle challenges such as drug developme

Stand Insurance

San Francisco

The company protects and insures homes against wildfire and hurricane risks by applying physics and AI to model true property risk, enabling more homes to be insurable.

Salient

San Francisco

Salient is an AI-driven workflow automation platform for lenders, starting with auto loan servicing. Since launching in 2023, it has surpassed $10M ARR, achieved cash-flow positivity, partnered with major U.S. lenders, and identified 35k+ C

Giga

San Francisco

Giga provides enterprise customer support by deploying AI agents, handling over 1 million tickets monthly, and counting industry leaders like Postman and Zepto among its clients, with rapid scaling backed by investors including Garry Tan and Nexus Venture Partners.

Zip

San Francisco

Zip, founded in 2020, pioneered procurement orchestration and leads $50B+ TAM, serving enterprises such as Instacart, Sephora, Reddit, Lyft, and brands like Airbnb, Facebook, Google. Valued at $2.2B with $370M in funding from Y Combinator,

Artisan

San Francisco

Artisan builds AI employees called Artisans and aims to replace the SaaS stack with a single integrated platform, starting with outbound sales; it consolidates every sales SaaS into one platform, framing it as next Industrial Revolution and

Noon

San Francisco

Noon (formerly Weaver) is an AI-native product design tool that links design and code so product teams can go from idea to shipped interface.

Imbue

San Francisco

This company aims to rekindle the dream of personal computing by making reliable software creation accessible to all, empowering humans in an AI era with powerful computing tools and researching verification of LLM-generated code to ensure

Counsel Health

San Francisco

Counsel is building an AI-driven healthcare practice to scale care delivery and provide rapid, personalized medical advice, leveraging partnerships with leading healthcare organizations and collaborative clinician–AI models; founded 2023, r

Delve

San Francisco

Delve is an AI-native compliance company helping 700+ fast-growing firms achieve SOC 2, HIPAA, ISO, GDPR, and other standards in days, not months; trusted by Lovable, Bland, and Wispr Flow, and building an AI-native platform to automate com

E2B

San Francisco

E2B is a Series A startup building the next hyperscaler for AI agents. It has seven figure revenue and has raised over $32M from investors including Insight Partners, serving Perplexity, Hugging Face, Manus, and Groq in San Francisco and Pr

Casca

San Francisco

Casca is building AGI for banking, replacing legacy systems with AI-native tech that automates 90% of manual work. It emphasizes responsible AI with human-in-the-loop monitoring and is backed by Y Combinator, Peterson Ventures, The Sarah Sm

General Medicine

San Francisco

General Medicine is a healthcare store focused on transforming outpatient care access by providing fast, price-transparent guidance on the next best clinical steps for all patients, regardless of insurance, aiming to speed care and empower

Wordware

San Francisco

Wordware offers a web-hosted IDE that lets non-technical domain experts collaborate with AI engineers to build task-specific AI agents, treating prompting as a programming language for natural language programming and agent orchestration.

Slash

San Francisco

Slash is a fintech company building industry-specific business banking, backed by YC, NEA, Stanford University, and others; it powers over three billion dollars a year in business purchasing and is among the fastest growing fintechs.

AfterQuery

San Francisco

AfterQuery builds datasets and experimentation to advance frontier LLM and AI-agent workflows, constructing complex data-infrastructure for agentic and hard-reasoning tasks. It partners with five AI labs and is YC's infrastructure partner, led by teams from top banks and quant firms.

Further

San Francisco

FurtherAI is a domain-specific AI company for the insurance industry, helping insurers, reinsurers, MGAs, and brokers drive better decisions at scale. Backed by a16z, Y Combinator, Nexus, and Converge, it supports customers writing over $15

Judgment Labs

San Francisco

Judgment Labs provides infrastructure for Agent Behavior Monitoring (ABM) to observe post-deployment autonomous-agent behavior at scale, serving hundreds of teams. It has raised over $30 million from notable investors and positioned as a le

FurtherAI

San Francisco

FurtherAI is a domain-specific AI company for the insurance industry, helping insurers, reinsurers, MGAs, and brokers drive better decisions at scale. Backed by a16z, Y Combinator, Nexus, and Converge, it supports customers writing over $15

Unify

San Francisco

Unify is an AI-first go-to-market platform that treats growth as a science, powering pipeline for leading teams such as Airwallex, Cursor, Perplexity, Together AI, and Guru. Founded Jan 17, 2023 by Austin Hughes and Connor Heggie, with a Li

Moonlake

San Francisco

The company builds multimodal reasoning models, developing AI systems that can reason across multiple modalities and integrate diverse data types. This focus positions it in a technically advanced area of AI development.

Fulcrum Tech

San Francisco

The company develops an AI platform that automates administrative tasks for insurance brokerages, with strong penetration in enterprise brokerages. It recently raised a Series A and aims to expand in the $1.5 trillion insurance market.

Indent

San Francisco

Indent is a platform for large engineering teams, used for incident response, code review, and data analysis with minimal setup. It provides a cloud AI software engineer that handles the entire job, including real-world tasks like analyzing

Mem0

San Francisco

Mem0 provides a universal, self-improving memory layer for LLM applications, enabling personalised AI experiences while reducing costs and boosting user delight. It markets itself as "The memory layer for Personalized AI."

Juicebox

San Francisco

Juicebox is an AI-powered recruitment company founded by Ishan Gupta and David Paffenholz, aiming to disrupt recruiting with AI that can reason and take actions. It serves 2,500+ clients, seven-figure revenue, is cashflow positive, and has

Vultron

San Francisco

Vultron helps federal contractors win contracts by delivering compliant proposal drafts and compressing weeks of work into days. It is trusted by 400+ federal contractors and has enabled $2.2B in contract wins, using proprietary models trai

Sauron

San Francisco

Sauron provides residential security via autonomous robots and cars, led by alumni of Zipline, Tesla, Apple, and Google. Incubated by Kevin Hartz and Atomic, it has raised rounds totaling at least $40M from investors including A*, 8VC, and

Encord

San Francisco

Encord offers a multimodal data labeling, curation and evaluation platform for AI, built by quants, physicists and computer scientists; backed by CRV and YC, it is SOC 2, HIPAA and GDPR compliant and serves customers including Synthesia and