Watertown, Massachusetts, United States · Hybrid
$195k–$275k/yr
Who we are: Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically im…
Skills: IT Strategy, Veeva Vault, Clinical Trials, GxP, Regulatory Compliance
Psivant Therapeutics, Inc.Watertown, Massachusetts, United States · Hybrid
$150k–$185k/yr
PsiThera is seeking a consultant computational medicinal chemist with expertise in drug discovery, molecular simulations and AI/ML to join our dynamic, multidisciplinary team. Our science, our team, and our mission are f…
Skills: Computer Aided Drug Design, Medicinal Chemistry, Molecular Simulations, Artificial Intelligence, Machine Learning
Psivant Therapeutics, Inc.Watertown, Massachusetts, United States · Hybrid
$179k–$200k/yr
PsiThera is seeking a talented and creative medicinal chemist with a strong track record of advancing peptide therapeutics and small molecule drug discovery projects from initial hits through to development candidate sel…
Skills: Medicinal chemistry, Peptide therapeutics, Small molecule drug discovery, Synthetic chemistry, Structure-based drug design
Watertown, Massachusetts, United States · On-site
$155k–$210k/yr
Who We Are ButcherBox is a certified B Corp headquartered in Boston, and honored to be celebrating our fourth year in a row on Inc.'s list of Best Workplaces. At ButcherBox, we believe in better. That’s why we deliver 10…
Skills: Product Management, E-commerce Strategy, DTC Experience, Shopify Liquid, Stakeholder Management
Watertown, Massachusetts, United States · On-site
Flexcompute is a cutting-edge technology startup that specializes in ultra-fast simulation technology. Our products are utilized by companies in designing and optimizing technology products, with applications ranging fro…
Skills: Python, AWS, Docker, Kubernetes, Terraform
Watertown, Massachusetts, United States · Hybrid
Flexcompute is a cutting-edge technology startup that specializes in ultra-fast simulation technology. Our products are utilized by companies in designing and optimizing technology products, with applications ranging fro…
Skills: Python, C++, Rust, Go, Java
Watertown, Massachusetts, United States · On-site
Flexcompute is a cutting-edge technology startup that specializes in ultra-fast simulation technology. Our products are utilized by companies in designing and optimizing technology products, with applications ranging fro…
Skills: Python, C++, Rust, Go, Java
Watertown, Massachusetts, United States · On-site
Flexcompute is a cutting-edge technology startup that specializes in ultra-fast simulation technology. Our products are utilized by companies in designing and optimizing technology products, with applications ranging fro…
Skills: Python, C++, Rust, Go, Java
Watertown, Massachusetts, United States · On-site
Flexcompute is leading the transformation of engineering simulation with our revolutionary ultra-fast simulation technology. Our flagship products, including the industry-leading Computational Fluid Dynamics (CFD) softwa…
Skills: Java, Python, C++, AWS, Web API Architecture
Watertown, Massachusetts, United States · On-site
Flexcompute is a cutting-edge technology startup that specializes in ultra-fast simulation technology. Our products are utilized by companies in designing and optimizing technology products, with applications ranging fro…
Skills: 3D-IC reliability, Computational multi-physics, GPU acceleration, Machine learning, FEA
Watertown, Massachusetts, United States · Remote Solely
Flexcompute is a cutting-edge technology company that specializes in ultra-fast simulation technology. Our products are utilized by companies in designing and optimizing technology products, with applications ranging fro…
Skills: Tidy3D, Python, Electromagnetic simulation, FDTD, Meshing
Watertown, Massachusetts, United States · Hybrid
Flexcompute is a cutting-edge technology startup that specializes in ultra-fast simulation technology. Our products are utilized by companies in designing and optimizing technology products, with applications ranging fro…
Skills: Enterprise Sales, Outbound Prospecting, Sales Strategy, Negotiation, Presentation Skills
Watertown, Massachusetts, United States · Hybrid
About Flexcompute Flexcompute is redefining the future of hardware engineering by delivering GPU-native, high-fidelity simulation tools. Flow360 accelerates aerodynamic and multi-physics workflows across aerospace, autom…
Skills: Cold Outreach, Lead Generation, Prospecting, CRM Management, Pipeline Management
Watertown, Massachusetts, United States · On-site
$158k–$184k/yr
Senior / Principal Scientist Biochemistry About Treeline Treeline Biosciences is an innovative biotechnology company, founded by an experienced team of biopharmaceutical scientists and executives, committed to developing…
Skills: Biochemistry, Drug discovery, Enzyme kinetics, Binding assays, Small molecule inhibitors
Watertown, Massachusetts, United States · Remote OK
$154k–$263k/yr
The Role AI Product Manager This role will drive development of Dyno’s AI products for biological design. You’ll work across modeling, software, and experimental validation to build systems that scientists use and trust.…
Skills: AI Product Management, Computational Biology, Bioinformatics, Software Development, API Design
Watertown, Massachusetts, United States · Remote OK
$100k–$115k/yr
Dynamo Software is a leading global FinTech Research and Portfolio Management SaaS provider offering an industry-tailored, highly configurable SaaS platform solving challenges across the alternative investment landscape.…
Skills: Private Equity Accounting, Partnership Investment Accounting, Financial Reporting, Fund Administration, Excel
Watertown, Massachusetts, United States · Remote OK
$80k–$105k/yr
Dynamo Software is a leading global FinTech Research and Portfolio Management SaaS provider offering an industry-tailored, highly configurable SaaS platform solving challenges across the alternative investment landscape.…
Skills: Investment Partnership Accounting, Data Migration, Excel, Financial Software Implementation, Client Relationship Management
Watertown, Massachusetts, United States · Hybrid
$45k–$60k/yr
Job DetailsJob Location: Watertown Headquarters - Watertown, MA 02472Position Type: Full TimeEducation Level: Not SpecifiedSalary Range: $45,000.00 - $60,000.00 Salary/yearTravel Percentage: NegligibleJob Shift: AnyJob C…
Skills: Microsoft 365, Power Automate, Troubleshooting, Technical Documentation, Workflow Automation
Watertown, Massachusetts, United States · On-site
$235k–$335k/yr
Who we are: Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically im…
Skills: AI Strategy, LLM Platforms, Prompt Engineering, Agentic Frameworks, Software Development
Watertown, Massachusetts, United States · On-site
$75k–$125k/yr
\n About Tutor We believe general-purpose, generally-intelligent robots will be built in our lifetimes. Robots will work in our factories, move our goods, walk on our streets and eventually be in our homes. To build that…
Skills: Outbound Prospecting, Account-Based Marketing, Pipeline Generation, Strategic Account Development, CRM Management
Watertown, Massachusetts, United States • Hybrid
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The IT Director will serve as the senior IT business partner for the Development organization, defining and driving the technology roadmap across clinical and regulatory functions. They will lead the implementation and management of validated systems such as Veeva Vault while partnering with business leads to integrate AI-enabled solutions.
Candidates must have 12+ years of IT experience in a biotech or pharmaceutical setting, specifically supporting clinical development through Phase 3 and NDA submission. Strong expertise in Veeva Vault, GxP regulatory standards, and the ability to manage complex vendor relationships are essential.
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.
Kymera is seeking an IT Director, Development Business Partner to serve as the senior IT leader embedded within the Development organization. This is a high-impact, strategic role for someone who has navigated the full arc of clinical-stage growth: from early-phase trials through Phase 3, NDA submission, and commercialization. The ideal candidate brings deep expertise in development technology, hands-on experience with Veeva Vault, a strong command of validated systems and regulatory requirements, and the vision to reimagine what those systems and processes can look like in the age of AI.
Reporting to the Senior Director of IT Applications, this person will own the technology strategy and execution across the Development portfolio, build trusted partnerships with Clinical Operations, Clinical/Medical Development, Quality, Biometrics, Data Management, Regulatory, and more, and serve as a thought partner to the IT leadership team as Kymera scales.
Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.
Compensation
Inventing a new class of medicines using Targeted Protein Degradation
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on delivering oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years.
Offices: 500 North Beacon Street, 4th Floor, Watertown, MA 02472, US
Based on 23 listings with disclosed salaries, most technology jobs in Watertown, MA pay between $80k–$205k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 43 open technology positions in Watertown, MA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Flexcompute, Tutor, TSMG Holding, Dynamo Software, Dyno Therapeutics, among others. Browse the listings above to see every active employer.
Yes — 18 of the 43 open technology positions offer remote or hybrid work (7 remote, 11 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
