Holly Springs, North Carolina, United States · On-site
$136k–$184k/yr
Career CategoryManufacturingJob Description HOW MIGHT YOU DEFY IMAGINATION? You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills…
Skills: GMP Material Handling, Manufacturing Logistics, Inventory Management, Operational Excellence, Lean Manufacturing
Holly Springs, North Carolina, United States · On-site
$73k–$99k/yr
Career CategoryEngineeringJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious…
Skills: Upstream Cell Culture, Process Development, Biopharmaceutical Manufacturing, GMP Manufacturing, Mammalian Cell Culture
Holly Springs, North Carolina, United States · On-site
Position Overview Join a high-growth biomanufacturing site and help ensure safe, compliant, and reliable production. As a Manufacturing Specialist I, you’ll be a hands-on problem solver who supports day-to-day operations…
Skills: cGMP Manufacturing, SAP, Continuous Improvement, CAPA, Change Management
Holly Springs, North Carolina, United States · On-site
$111k–$150k/yr
Career CategoryEngineeringJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious…
Skills: cGMP Compliance, Root Cause Analysis, Change Control, CAPA Management, Risk Assessment
Holly Springs, North Carolina, United States · On-site
Position Overview The Senior Specialist II, QC LIMS is a site-level and cross-functional leader for the Laboratory Information Management System (LIMS), operating with minimal oversight and in accordance with applicable …
Skills: LabWare LIMS, GMP Compliance, Data Integrity, System Configuration, Validation Protocols
Holly Springs, North Carolina, United States · On-site
Position Overview Drive excellence in a fast-paced, 24/7 manufacturing environment. As a Manufacturing Support Associate III, you will lead critical readiness and operational activities that keep production compliant, re…
Skills: Manufacturing Operations, Troubleshooting, Batch Planning, Commissioning And Qualification, Good Manufacturing Practice (GMP)
Holly Springs, North Carolina, United States · On-site
Results Physiotherapy, a brand partner of Upstream Rehabilitation, is looking for a Physical Therapy Technician to join our team in Holly Springs, NC! Are you looking for a position in a service-based culture where you c…
Skills: Customer Service, Communication, Organization, Multitasking, Computer Proficiency
Holly Springs, North Carolina, United States · On-site
Results Physiotherapy, a brand partner of Upstream Rehabilitation, is looking for a Physical Therapy Technician to join our team in Holly Springs, NC! Are you looking for a position in a service-based culture where you c…
Skills: Patient Care, Customer Service, Communication Skills, Organizational Skills, Multitasking
Holly Springs, North Carolina, United States · On-site
Position Overview Make a measurable impact on patient health by leading a high-performing team in a 24/7, state-of-the-art drug product facility. If you thrive on building people, solving problems, and delivering safe, h…
Skills: cGMP Leadership, Drug Product Formulation, Visual Inspection, Team Coaching, Problem Solving
Holly Springs, North Carolina, United States · On-site
$86k–$116k/yr
Career CategoryOperationsJob DescriptionJoin Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious …
Skills: Root Cause Analysis, CAPA Development, Technical Writing, Environmental Monitoring, Microbiology Principles
Holly Springs, North Carolina, United States · On-site
Overview Allied Universal®, North America’s leading security and facility services company, offers rewarding careers that provide you a sense of purpose. While working in a dynamic, welcoming, and collaborative workplace…
Skills: Access Control, Dispatching, Customer Service, Emergency Response, Incident Documentation
Holly Springs, North Carolina, United States · On-site
$86k–$116k/yr
Career CategoryManufacturingJob Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with seri…
Skills: Electronic Batch Records, PAS-X (Korber), MES Integration, cGMP Manufacturing, SOP Creation
Holly Springs, North Carolina, United States · On-site
Do you want to work with a company that tackles fascinating problems and find solutions to complex challenges? Seqirus has an exciting opportunity to join our expanding team in Holly Springs, NC. With an advanced manufac…
Skills: Validation, Commissioning, Qualification, Root Cause Analysis, SOP Development
Holly Springs, North Carolina, United States · On-site
$20/hr–$23/hr
You’ve invested a lot of time and energy in your education. Now you want the chance to make your mark. We offer challenging opportunities for you to learn and grow professionally. In our programs, you’ll be immersed in a…
Skills: Patient Safety, Pharmacy Professional Practice, Regulatory Requirements, Quality Assurance, Customer Service
Holly Springs, North Carolina, United States · On-site
Duke Neurology is seeking a board eligible/board certified Neurologist with Headache fellowship training to join its expanding outpatient neurology practice in the rapidly growing Raleigh-Durham, NC area. See patients in…
Skills: Neurology, Headache Management, Patient Care, Interpersonal Communication, Professionalism
Holly Springs, North Carolina, United States · Hybrid
$144k–$178k/yr
Career CategoryInformation SystemsJob Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living wit…
Skills: Veeva Vault, Data Warehousing, SQL, ETL/ELT, AWS
Holly Springs, North Carolina, United States · On-site
Reporting to the Front-Line Quality Assurance (FLQA) Senior Manager, the QA Specialist is an individual contributor providing strategic and technical support for the Quality Control, FacOps, and Warehouse departments at …
Skills: cGMP Compliance, Deviation Management, CAPA, Change Control, Quality Risk Assessment
Holly Springs, North Carolina, United States · On-site
Position Overview The People and Culture (P&C) Operations Associate provides entry-level operational support to employees, managers, and the P&C team. This role executes routine HR transactions in Workday, responds to ba…
Skills: Workday, HR Operations, Data Entry, Onboarding, Offboarding
Holly Springs, North Carolina, United States · On-site
Position Overview The Sr Automation Engineer 1, MES provides support to the Drug Substance Manufacturing (DSM) facility. This includes implementation of changes to the Automation systems, updating design documents, execu…
Skills: DeltaV DCS, Manufacturing Execution System (MES), Syncade, SQL Stored Procedures, XPath Matching
Holly Springs, North Carolina, United States · On-site
Position Overview The Automation Engineer 3, BMS/VDS provides support for the sitewide Building Management System (BMS) and Validated Data System (VDS). This includes implementation of changes to the utility and facility…
Skills: BMS, VDS, System Administration, Code Configuration, GMP Compliance
Holly Springs, North Carolina, United States • On-site
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Lead 24/7 GMP material handling operations, overseeing the receipt, storage, and delivery of materials to support drug substance manufacturing. Responsible for organizational design, hiring, and ensuring operational readiness for a state-of-the-art facility start-up.
Requires a degree in Manufacturing & Operations with experience ranging from 2 to 12 years depending on the education level, plus at least 2 years of managerial experience. Preferred candidates have a background in biologics/pharmaceuticals and expertise in Lean Manufacturing and electronic inventory systems.
HOW MIGHT YOU DEFY IMAGINATION?
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience, and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Be part of Amgen's newest and most advanced drug substance manufacturing plant. The Amgen FleX Batch facility combines the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. The FleX Batch facility not only features the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it also integrates sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.
Senior Manager: Manufacturing – Material Handling
Live
What you will do
Let's do this. Let's change the world. As a Senior Manager of Manufacturing – Material Handling, you will provide leadership and guidance to the team responsible for 24/7 GMP material handling operations supporting manufacturing across the facility.
In this vital role as a member of the Manufacturing leadership team, the Senior Manager, Manufacturing – Material Handling, will collaborate cross-functionally to enable the manufacture of drug substance in a new state-of-the-art manufacturing facility. This role is responsible for leading and developing Material Handling Front-Line Managers who oversee teams supporting the receipt, staging, movement, storage, inventory control, and delivery of GMP materials between the warehouse and manufacturing operations. Additionally, you will be accountable for organizational design, hiring, development, and training compliance of the Material Handling organization to ensure safe, reliable, and uninterrupted manufacturing operations. The position will also provide leadership and oversight for operational readiness activities to ensure successful facility start-up and sustained commercial manufacturing performance.
Responsibilities:
Develop and retain a diverse, high-performing Material Handling organization in alignment with operational readiness schedules to support successful facility startup and commercial GMP operations.
Foster a strong safety, quality, and compliance culture while championing continuous improvement across all Material Handling activities.
Collaborate as one team with Manufacturing, Warehouse Operations, Quality, Engineering, Supply Chain, Process Development, Automation, and network partners to ensure reliable execution of manufacturing operations.
Lead the execution and continuous improvement of end-to-end material flow processes, ensuring the right materials are available at the right location and time to support uninterrupted manufacturing.
Oversee inventory accuracy, material reconciliation, cycle counting, and GMP inventory control processes while ensuring compliance with regulatory and internal quality requirements.
Own the Manufacturing Material Transfer Equipment program, ensuring equipment lifecycle management, availability, qualification, maintenance coordination, and operational readiness.
Partner with Supply Chain and Warehouse Operations to optimize material staging, replenishment strategies, and production scheduling while minimizing operational risk.
Provide leadership in troubleshooting operational issues affecting material availability and establish robust escalation and 24/7 support processes.
Lead investigations related to material handling deviations, inventory discrepancies, and material management events while driving effective root cause analysis and corrective actions.
Develop and implement departmental strategies aligned with organizational objectives while driving Operational Excellence, Lean Manufacturing, and continuous improvement initiatives.
Lead and support internal and regulatory inspections for areas of responsibility, including inspection readiness, response development, and sustainable compliance strategies.
Deliver against organizational financial commitments while optimizing labor, inventory utilization, and operational efficiency.
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The experienced professional we seek is a collaborative partner with these qualifications.
Basic Qualifications:
Doctorate degree and 2 years of Manufacturing & Operations experience Or
Master’s degree and 6 years of Manufacturing & Operations experience Or
Bachelor’s degree and 8 years of Manufacturing & Operations experience Or
Associate's degree and 10 years of Manufacturing & Operations experience Or
High School diploma/GED and 12 years of Manufacturing & Operations experience
AND 2 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources
Preferred Qualifications
Demonstrated managerial experience supporting GMP manufacturing operations in a biologics or pharmaceutical manufacturing environment.
Experience leading GMP material handling, manufacturing logistics, inventory management, or warehouse operations supporting manufacturing.
Demonstrated experience implementing Operational Excellence, Lean Manufacturing, and continuous improvement methodologies.
Experience with electronic inventory management systems (SAP, MES, electronic batch records, barcode/RFID technologies, or equivalent).
Working knowledge of GMP material management, inventory control, material traceability, and regulatory compliance requirements.
Cross-functional experience partnering with Manufacturing, Supply Chain, Engineering, Quality, and Process Development organizations.
Excellent communication, leadership, organizational, and problem-solving skills with the ability to influence across multiple organizations.
Demonstrated ability to develop high-performing teams and foster an inclusive, accountable, and collaborative culture.
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
Vast opportunities to learn and move up and across our global organization
Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits
Apply now
for a career that defies imagination
In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.
careers.amgen.com
#AmgenNorthCarolina
#WeareBiotech
Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We helped establish the biotechnology industry, and we remain on the cutting-edge of innovation, using technology and human genetic data to push beyond what’s known today. Our investment in research and development has yielded a robust pipeline that builds on our existing portfolio of medicines to treat cancer, heart disease, osteoporosis, inflammatory diseases and rare diseases. Amgen is one of 30 companies comprising the Dow Jones Industrial Average®, and part of the Nasdaq-100 Index®. In 2024, Amgen was named one of the “World’s Most Innovative Companies” by Fast Company and one of “America’s Best Large Employers” by Forbes. For more information, visit Amgen.com and follow us on X, LinkedIn, Instagram, TikTok, YouTube and Threads. 🔗 Community Guidelines: https://wwwext.amgen.com/community-guidelines 🔗Global Privacy Statement Directory: www.amgen.com/dp Special Advisory: Please be cautious of scam recruitment offers claiming to be from Amgen. Such scams may come from various sources, including fake websites and/or unsolicited emails and seek to obtain personal data or payment from victims by offering jobs that do not exist. Please be advised that Amgen would never ask for payment to progress a job application. When in doubt, please check to see if the position in question is posted on this website before applying. Additionally, please report any suspicious recruiting activity to https://complaint.ic3.gov/ and thank you for your assistance.
Offices: One Amgen Center Drive, Thousand Oaks, CA 91320, US · 1120 Veterans Blvd, South San Francisco, CA 94080, US · 34 Commerce Way, Woburn, MA 01801, US · Avenida Calle 100 7-81, Bogota, Bogota, D.C. 110221, CO · Minervum 7061, Breda, North Brabant 4817 ZK, NL
Based on 62 listings with disclosed salaries, most healthcare jobs in Holly Springs, NC pay between $71k–$156k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 150 open healthcare positions in Holly Springs, NC listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Amgen, FUJIFILM Electronic Materials U.S.A., Inc., CSL, CVS Health, Roche, among others. Browse the listings above to see every active employer.
Yes — 7 of the 150 open healthcare positions offer remote or hybrid work (1 remote, 6 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
