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Engineering Jobs in South San Francisco, CA (Now Hiring) — 276 open

Zipline logoZipline

Senior Manager, Network Strategy & Transportation

South San Francisco, California, United States · On-site

$140k–$180k/yr

Senior+$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: Network Design, Transportation Procurement, Freight Sourcing, Logistics Strategy, Supply Chain Optimization

Zipline logoZipline

Senior Manager, Field Logistics

South San Francisco, California, United States · On-site

$140k–$180k/yr

Senior+$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: Logistics Management, Supply Chain Strategy, 3PL Management, Inventory Deployment, Field Operations

Zipline logoZipline

Forward Deployed AI Engineer, Operations

South San Francisco, California, United States · On-site

$113k–$300k/yr

Senior$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: Generative AI, Large Language Models, Python, TypeScript, JavaScript

Zipline logoZipline

Maps Intern (Fall 2026)

South San Francisco, California, United States · On-site

Entry level$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: Path Planning Algorithms, Algorithmic Optimization, Coding, Programming, Automated Testing

Zipline logoZipline

Head of Flight Test Engineering

South San Francisco, California, United States · On-site

$180k–$225k/yr

Senior$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: Flight Test Engineering, System Validation, Test Automation, Risk Assessment, Data Analysis

Xaira Therapeutics logoXaira Therapeutics

Lab Automation - Vision AI Engineer Intern

South San Francisco, California, United States · On-site

$10k–$13k/mo

Entry level$1.0B raised

About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…

Skills: Computer Vision, Multimodal AI, Python, PyTorch, TensorFlow

Zipline logoZipline

Software Engineer Intern (Fall 2026)

South San Francisco, California, United States · On-site

Entry level$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: React Native, Python, Go, Computer Science Fundamentals, Software Development

Culture Biosciences logoCulture Biosciences

Procurement Engineer

South San Francisco, California, United States · On-site

$115k–$150k/yr

Senior$102M raised

About Us: Culture’s mission is to simplify and accelerate bioprocess development to enable our customers to bring their biopharmaceutical products to market faster. With a focus on upstream cell culture process developme…

Skills: Procurement, Sourcing, Supplier Management, Contract Negotiation, ERP Systems

Xaira Therapeutics logoXaira Therapeutics

Senior Automation Engineer

South San Francisco, California, United States · On-site

$152k–$190k/yr

Senior$1.0B raised

About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…

Skills: Lab Automation, Liquid Handling, Python, C#, SQL

Zipline logoZipline

System Test Automation Intern (Fall 2026)

South San Francisco, California, United States · On-site

Entry level$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: Rust, Python, Pytest, Unittest, Linux

Zipline logoZipline

Senior Hardware Recruiting Partner

South San Francisco, California, United States · On-site

$135k–$180k/yr

Senior$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: Full-cycle Recruiting, Technical Sourcing, Stakeholder Management, Talent Mapping, Workforce Planning

Zipline logoZipline

Systems Engineer

South San Francisco, California, United States · On-site

$160k–$260k/yr

Senior$2.1B raised

About Zipline Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We des…

Skills: Systems Engineering, Requirements Management, Electromechanical Systems, Safety Critical Systems, Validation Processes

Xaira Therapeutics logoXaira Therapeutics

Director, Protein Sciences

South San Francisco, California, United States · On-site

$196k–$245k/yr

Senior+$1.0B raised

About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…

Skills: Protein Production, Protein Characterization, Antibody Design, High Throughput Screening, Analytical SEC

NewLimit logoNewLimit

Scientist, Functional Genomics

South San Francisco, California, United States · On-site

$130k–$170k/yr

Senior$247M raised

Company info NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to resto…

Skills: Functional Genomics, Molecular Cloning, Next-Generation Sequencing, CRISPR-Cas, Epigenetic Reprogramming

Cogent Scientific logoCogent Scientific

Large Molecule Scientific Lead

South San Francisco, California, United States · On-site

$140k–$150k/yr

Senior+

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry by cultivating and empowering exceptional scientists to del…

Skills: Antibody-Drug Conjugates, Bioconjugation, SAR Studies, Linker Design, Drug Development

MSD logoMSD

Senior Scientist, Antibody Discovery

South San Francisco, California, United States · On-site

$131k–$207k/yr

SeniorVisa sponsorship

Job Description We are on a quest for cures and are committed to be the world’s premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with t…

Skills: Antibody Discovery, Antigens, B Cells, Flow Cytometry, High-Throughput Assays

Roche logoRoche

Principal Project Scheduler

Oceanside, California, United States · On-site

$120k–$223k/yr

Senior+$7.8B raised

This role is a valuable part of Roche's Global Engineering team within Pharma Technical Operations, which is committed to delivering world-class capital projects that enable our GMP manufacturing excellence and innovatio…

Skills: Project Scheduling, Primavera P6, MS Project, Lean Construction, Last Planner System

Thermo Fisher Scientific logoThermo Fisher Scientific

Staff Scientist, Bioinformatics

South San Francisco, California, United States · On-site

$129k–$145k/yr

Senior$20B raised

Work Schedule Standard (Mon-Fri) Environmental Conditions Office Job Description As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our coll…

Skills: Bioinformatics Pipelines, Next-Generation Sequencing, Python, Perl, Shell Scripting

MSD logoMSD

Senior Scientist, Antibody Discovery

South San Francisco, California, United States · On-site

$131k–$207k/yr

SeniorVisa sponsorship

Job Description We are on a quest for cures and are committed to be the world’s premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with t…

Skills: Antibody Discovery, Antigens, B Cells, Flow Cytometry, High-Throughput Assays

Roche logoRoche

Senior Machine Learning Engineer, AI Enablement

South San Francisco, California, United States · Hybrid

$148k–$274k/yr

Senior$7.8B raised

We advance science so that we all have more time with the people we love. A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need to…

Skills: Machine Learning, AI Frameworks, Statistics, GPU Optimization, Kubernetes

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Showing 1–20 of 276

Zipline logo

Senior Manager, Network Strategy & Transportation

Zipline

South San Francisco, California, United States • On-site

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Senior+

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  • $140k–$180k/yr
  • Full-time
  • Equity Compensation, Discretionary Annual Bonus, Performance Bonuses, Sales Incentives, Medical Insurance, Dental Insurance
  • Posted 1d ago
  • ~40 hrs/week

Responsibilities

Own the strategic design and performance of Zipline's global logistics network, including transportation, freight procurement, and circular supply chain operations. Develop long-term strategies to optimize cost, speed, and resiliency while leading a high-performing logistics team.

Requirements

Requires over 10 years of experience in transportation, network design, or logistics leadership with deep expertise in carrier management and freight procurement. Candidates must possess strong quantitative modeling skills and the ability to lead complex, cross-functional global initiatives.

Full job description

About Zipline

Zipline is the world’s largest and most experienced drone delivery service. We are on a mission to serve all humans equally by ensuring access to food, medicine and essential goods anytime, anywhere. We design, build, and operate the world’s largest autonomous logistics system, delivering critical supplies quickly and reliably. Today, Zipline operates on four continents, makes a delivery somewhere in the world every 30 seconds, and has completed millions of deliveries to date, including blood, vaccines, medical supplies, food, and retail products. 

Our customers include the world’s largest and most prominent healthcare systems, governments, retailers, restaurants and global businesses who rely on us to save lives, reduce emissions, increase economic opportunity, and provide delivery from point A to point B as fast as possible. The drone is only 15% of what we’ve built to enable seamless, reliable, global operations.

Our system strengthens supply chains, reduces congestion, and gives people time back. With more than 140 million commercial autonomous miles safely flown, Zipline is redefining access to healthcare, consumer products, and food across the globe.

We operate at a global scale and are looking for practical problem solvers who thrive on real-world challenges and rapid growth. Our team is motivated by building systems that have a direct, meaningful impact on people’s lives and by scaling the future of logistics. We are seeking people who sculpt from first principles, enjoy facing adversity, and can do the impossible at record breaking speeds.

About the Role

The Senior Manager, Logistics Network Strategy will own the strategic design and performance of Zipline's logistics network, including transportation, freight procurement, inventory flow design, asset recovery, and circular supply chain operations.

This leader will develop the long-term logistics strategy that supports global growth while optimizing cost, speed, resiliency, and asset utilization. They will partner closely with Supply Chain, Manufacturing, Finance, and Operations to build the systems and infrastructure required for the next phase of Zipline's scale.

What You'll Do

  • Own logistics network strategy across domestic and international operations.
  • Design and optimize transportation flows between suppliers, factories, distribution centers, depots, and operational sites.
  • Lead carrier strategy, transportation procurement, freight sourcing, and logistics partnerships.
  • Develop network models to support expansion planning, inventory deployment, and service-level objectives.
  • Build logistics cost models and drive network optimization initiatives.
  • Establish transportation performance metrics and governance processes.
  • Own circular supply chain operations, including asset recovery, field returns, reusable packaging flows, and remanufacturing logistics.
  • Identify opportunities to improve asset utilization and reduce total landed cost across the network.
  • Partner with Finance to develop long-range logistics planning and investment strategies.
  • Build and lead a high-performing team responsible for transportation, network analytics, and logistics strategy.

What You'll Bring

  • 10+ years of experience in transportation, network design, supply chain strategy, or logistics leadership.
  • Deep understanding of transportation operations, carrier management, and freight procurement.
  • Experience designing and optimizing complex logistics networks.
  • Strong quantitative and analytical capabilities, including modeling and scenario analysis.
  • Experience leading cross-functional initiatives with measurable business impact.
  • Ability to translate strategic objectives into scalable operational systems.
  • Excellent executive communication and stakeholder management skills.
  • Passion for solving complex logistics challenges at global scale.

Success in This Role

Success means enabling Zipline to scale globally through a logistics network that is cost-efficient, resilient, data-driven, and capable of supporting rapid growth. You will create the transportation and network infrastructure that allows products, assets, and inventory to move seamlessly throughout the world.

 

What Else You Need to Know   

The starting cash range for this role is $140,000 - $180,000. Please note that this is a target, starting cash range for a candidate who meets the minimum qualifications for this role. The final cash pay for this role will depend on a variety of factors, including a specific candidate's experience, qualifications, skills, working location, and projected impact. The total compensation package for this role may also include: equity compensation; discretionary annual or performance bonuses; sales incentives; benefits such as medical, dental and vision insurance; paid time off; and more.
 
Zipline is an equal opportunity employer and prohibits discrimination and harassment of any type without regard to race, color, ancestry, national origin, religion or religious creed, mental or physical disability, medical condition, genetic information, sex (including pregnancy, childbirth, and related medical conditions), sexual orientation, gender identity, gender expression, age, marital status, military or veteran status, citizenship, or other characteristics protected by state, federal or local law or our other policies.
 
We value diversity at Zipline and welcome applications from those who are traditionally underrepresented in tech. If you like the sound of this position but are not sure if you are the perfect fit, please apply!

Related keywords

Logistics NetworkTransportation StrategyFreight ProcurementCircular Supply ChainAsset UtilizationLanded CostSupply Chain ManagementNetwork ModelingAutonomous LogisticsGlobal OperationsInventory DeploymentService-Level ObjectivesGovernance ProcessesRemanufacturing LogisticsStrategic Sourcing

About Zipline

LinkedInVisit site
Industry
Transportation, Logistics, Supply Chain and Storage
Company size
1,001-5,000 employees
Headquarters
South San Francisco, California
LinkedIn followers
149,535
Total funding
$2.1B

Zipline was founded to create the first logistics system that serves all humans equally. Our aim is to solve the world’s most urgent and complex access challenges. Leveraging expertise in robotics and autonomy, Zipline designs, manufactures and operates the world’s largest automated delivery system. Zipline serves tens of millions of people around the world and is making good on the promise of building an equitable and more resilient global supply chain. From powering Rwanda’s national blood delivery network and Ghana’s COVID-19 vaccine distribution, to providing on-demand home delivery for Walmart and enabling leading healthcare providers to bring care into the home in the United States, Zipline is transforming the way goods move. By transitioning to clean, electric, instant logistics, we can decarbonize delivery, decrease road congestion, and reduce fossil fuel consumption and air pollution, while providing equitable access for billions of people. The technology is complex but the idea is simple: a teleportation service that delivers what you need, when you need it. Zipline is inspiring people, governments, and businesses to imagine what is possible when goods can move as seamlessly as information. To join the team, check out our career page: https://flyzipline.com/careers/

Offices: 333 Corey Way, South San Francisco, California 94080, US

technologyroboticshealthcareengineeringsocialimpactdroneslogisticspharmaceuticalsmedicineafrica
View all jobs at Zipline

Frequently asked questions

How much do Engineering jobs in South San Francisco, CA pay?

Based on 212 listings with disclosed salaries, most engineering jobs in South San Francisco, CA pay between $120k–$250k per year. Individual offers vary with seniority, company size, and specialization.

How many Engineering jobs are open in South San Francisco, CA right now?

There are currently 276 open engineering positions in South San Francisco, CA listed on Clera. New openings are added daily as companies post roles.

Which companies are hiring for Engineering roles in South San Francisco, CA?

Companies currently hiring include Zipline, Roche, MSD, Xaira Therapeutics, Cellares, among others. Browse the listings above to see every active employer.

Are there remote or hybrid Engineering jobs in South San Francisco, CA?

Yes — 26 of the 276 open engineering positions offer remote or hybrid work (2 remote, 24 hybrid).

How do I apply for Engineering jobs in South San Francisco, CA?

Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.

Engineering jobs in other cities

New York, NYHouston, TXAustin, TXSan Francisco, CAAtlanta, GASan Diego, CASeattle, WAWashington, DCChicago, ILDallas, TX

Other jobs in South San Francisco, CA

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