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$86k–$155k/yr
Full-time
bachelor degree, postgraduate degree
Posted 33d ago
~40 hrs/week
Responsibilities
The Scientist designs and executes advanced laboratory and computational research focused on genomics, gene editing, and hematologic disorders. Responsibilities include performing multi-omics analyses, developing therapeutic base-editing strategies, and mentoring junior researchers.
Requirements
Requires a Bachelor's degree with 8 years of experience, a Master's with 6 years, or a PhD with 3 years of relevant experience. Candidates should possess a combination of wet lab biology and computational biology expertise, specifically in CRISPR and genomic data analysis.
Full job description
The Scientist independently designs, performs, and coordinates a broad range of advanced laboratory and computational research activities supporting cutting-edge genomics programs focused on hematologic disorders and cancer predisposition. Research efforts span multi-omics studies (genomics, transcriptomics, epigenomics) and genome editing. Particular emphasis is on characterizing novel genes and clonal lesions that drive clonal evolution, and on developing therapeutic base-editing strategies.
The Scientist develops and executes experimental strategies integrating both wet lab techniques and bioinformatics analyses, contributing to projects that span discovery through data interpretation. This role requires the ability to analyze, interpret, and present complex biological datasets, while actively contributing to experimental design, protocol development, and scientific reporting.
The ideal candidate brings primary expertise in either wet lab biology or computational biology, along with working knowledge of the complementary discipline (e.g., wet lab scientists with bioinformatics exposure, or computational scientists with hands-on laboratory experience), enabling effective collaboration across interdisciplinary teams.
About the lab:
This position is part of theMarcin Wlodarki Lab at St. Jude Children’s Research Hospital, which focuses on advancing our understanding of genetic and genomic drivers of hematologic disorders and cancer predisposition. The lab integrates translational research, functional genomics, and computational approaches to uncover disease mechanisms and improve patient outcomes. The lab PI directs the institution's clinicalBone Marrow Failure (BMF) Programand co-leads thehttps://www.stjude.org/research/progress/2023/shifting-the-paradigm-towards-individualized-gene-editing-therapies.html" target="_blank" rel="noopener noreferrer nofollow">PARADIGM gene editing program, creating a direct bridge between patient care and discovery science.
Design, coordinate, and execute research projects involving genetics/genomics, including gene editing technologies (e.g., CRISPR-Cas9 and base editing) and downstream analysis
Perform laboratory experiments and apply appropriate techniques; evaluate methodologies and recommend alternative approaches or tools as needed
Conduct bioinformatics and computational analyses of genomic datasets, including processing, organization, interpretation, and visualization of data
Contribute to the development, optimization, and implementation of new laboratory and computational protocols
Identify and extract relevant experimental data; ensure accuracy, quality, and integrity of datasets and analyses
Summarize and communicate research findings through reports, presentations, and contributions to manuscripts/publications
Support laboratory operations, including equipment maintenance, calibration and troubleshooting
Maintain inventory and ensure proper functioning of laboratory and computational resources
Train and mentor staff or junior researchers in laboratory techniques, data analysis methods, and best practices
Maintain regular and predictable attendance
Perform other related duties as assigned to support departmental and institutional goals
Minimum Education and/or Training:
Bachelor's degree in relevant scientific area is required
Minimum Experience:
Eight (8) years of relevant work experience is required
Six (6) years of relevant work experience is required with a Master's degree
Three (3) years of relevant work experience is required with a PhD
Preferred Qualifications:
Strong experience in genetics/genomics and gene editing technologies (CRISPR-Cas9, base editing, prime editing)
Proven experience in bioinformatics or computational biology, particularly genomic data analysis
A combination of wet lab and computational expertise
Demonstrated track record of scientific contributions (e.g., publications, project leadership, or impactful research outcomes)
Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist (Genomics / Gene Editing & Bioinformatics) - Wlodarski Lab.
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
ALSAC is the largest healthcare-related charity in the United States. Founded in 1957 by Danny Thomas, our sole mission is to raise the funds and awareness needed to operate and maintain St. Jude Children's Research Hospital®. While our headquarters can be found in Memphis, Tennessee, we have additional offices in more than 30 locations across the country and in Puerto Rico with positions in fundraising, marketing, digital, information technology, legal, finance and many other disciplines all supporting our lifesaving mission - Finding cures. Saving children. ®
At ALSAC, we believe in hiring the best and brightest from around the globe, and in 2020 we were named #1 on Fast Company's 100 Best Workplaces for Innovators. With a concerted focus on diversity and inclusion, we value and respect the contributions of all of our employees. Our work environment encourages everyone to be their authentic selves as we strive together towards a day when “no child dies in the dawn of life.”
As we look to the future, we understand that we must be relentlessly innovative. Our work helps fuel the groundbreaking research and treatment at St. Jude and ensures that families never receive a bill from St. Jude for treatment, travel, housing or food — because all a family should worry about is helping their child live.
View our career opportunities at https://www.stjude.org/jobs/alsac.html and follow ALSAC across social media using @stjude.
To learn more about the research hospital, follow St. Jude Children's Research Hospital on LinkedIn. For specific career opportunities available through the hospital, visit www.stjude.org/JoinOurMission.
Offices: 501 St. Jude Place, Memphis, TN 38105, US · 262 Danny Thomas Pl, Memphis, TN 38105, US · 2 Pine West Plaza, Suite 202, Albany, NY 12205, US · 53 Perimeter Center East, Suite 100, Atlanta, GA 30346, US · 9111 Jollyville Road, Suite 113, Austin, TX 78759, US
Research HospitalFundraisingPhilanthropyHealthcarePediatric OncologyChildhood CancerSickle Cell DiseaseCancer SurvivorshipCharityChildren's Charity
ALSAC is the largest healthcare-related charity in the United States. Founded in 1957 by Danny Thomas, our sole mission is to raise the funds and awareness needed to operate and maintain St. Jude Children's Research Hospital®. While our headquarters can be found in Memphis, Tennessee, we have additional offices in more than 30 locations across the country and in Puerto Rico with positions in fundraising, marketing, digital, information technology, legal, finance and many other disciplines all supporting our lifesaving mission - Finding cures. Saving children. ®
At ALSAC, we believe in hiring the best and brightest from around the globe, and in 2020 we were named #1 on Fast Company's 100 Best Workplaces for Innovators. With a concerted focus on diversity and inclusion, we value and respect the contributions of all of our employees. Our work environment encourages everyone to be their authentic selves as we strive together towards a day when “no child dies in the dawn of life.”
As we look to the future, we understand that we must be relentlessly innovative. Our work helps fuel the groundbreaking research and treatment at St. Jude and ensures that families never receive a bill from St. Jude for treatment, travel, housing or food — because all a family should worry about is helping their child live.
View our career opportunities at https://www.stjude.org/jobs/alsac.html and follow ALSAC across social media using @stjude.
To learn more about the research hospital, follow St. Jude Children's Research Hospital on LinkedIn. For specific career opportunities available through the hospital, visit www.stjude.org/JoinOurMission.
Offices: 501 St. Jude Place, Memphis, TN 38105, US · 262 Danny Thomas Pl, Memphis, TN 38105, US · 2 Pine West Plaza, Suite 202, Albany, NY 12205, US · 53 Perimeter Center East, Suite 100, Atlanta, GA 30346, US · 9111 Jollyville Road, Suite 113, Austin, TX 78759, US
Research HospitalFundraisingPhilanthropyHealthcarePediatric OncologyChildhood CancerSickle Cell DiseaseCancer SurvivorshipCharityChildren's Charity