B2B startups in San Francisco

Canvas

San Francisco

Canvas, a small team, is building AI Operating System for B2B sales, backed by Y Combinator, to automate boring parts of outbound so humans can focus on finding and connecting with prospects, via AI research agents and on-demand human SDRs.

Amplitude

San Francisco

Amplitude is a San Francisco-based digital analytics company founded in 2012 by Spenser Skates (CEO) and Curtis Liu (CTO). It went public in 2021, serves over 3,000 paying customers, and focuses on product analytics to help organizations bu

Stealth Worker

San Francisco

Information Security (Cyber Security), Compliance and Privacy (GDPR &…

GrubMarket

San Francisco

AI-powered technology enabler and digital transformer of American…

Zeplin

San Francisco

Deliver on the Promise of Design

Double Robotics

San Francisco

Telepresence robots

42

San Francisco

Analytics stack for omnichannel retailers and brands

Screenleap

San Francisco

One-click screen sharing with installation-free viewing on all devices

Reprompt

San Francisco

Reprompt builds AI Agents for location-based mapping, helping Radar and TomTom keep maps current with live POI data. It runs an AI agents platform (Web, Vision, Doc Reading; upcoming self-driving browser agents) led by Mapbox, Facebook, and

14.ai

San Francisco

14.ai, founded by Michael Fester and Marie Schneegans, builds customer support solutions for 1000x teams; backed by Y Combinator and SV Angel, with backers including founders from Vercel, Slack, Dropbox, and Algolia, and Fester previously c

Middleware

San Francisco

Middleware is a fast-growing San Francisco-based startup backed by a tier-1 investor, delivering insights and visibility into complex systems for B2B software and services infrastructure. Led by founder-CEO Laduram Vishnoi, who previously b

Capy

San Francisco

Scout is an AI-native software engineering agent that operates asynchronously on its own VM and tackles long-horizon tasks on large codebases.

Stacksync

San Francisco

Stacksync provides real-time, two-way data synchronization between CRMs and databases, serving engineers and RevOps teams. Founded by Ruben Burdin and Alexis Favre, the company focuses on data movement and enterprise integration.

Berry

San Francisco

Berry is a Y Combinator-backed startup serving SaaS companies worldwide. Led by co-founder and Chief Product Officer Ann Chan and founder Yan Fu, a former startup CTO, Berry scales services for SaaS firms using React, TypeScript, Python, RE

Mercoa

San Francisco

Mercoa is an embedded B2B payments platform that enables B2B fintechs to add BillPay and Accounts Payable to their products, serving accounting firms, neobanks, and vertical SaaS across construction, e-commerce, and home services.

OpenFunnel

San Francisco

OpenFunnel is a time-aware search engine for GTM teams that surfaces insights from time-based signals, delivering daily actionable findings. Trusted by over 1,000 users (including Central, Mintlify, and Everest Systems), it reveals pain poi

Modern Treasury

San Francisco

Modern Treasury builds payments operations solutions, focusing on payment operations as core to business. Described as a lean team, this positions the company as a focused provider in the payments operations space for businesses.

CTGT

San Francisco

CTGT Inc safeguards reputational risk from GenAI for organizations in the B2B software and services infrastructure market. Based in San Francisco as a seven-employee startup founded by Cyril Gorlla and Trevor Tuttle, Gorlla's efficient AI w

Decipher AI

San Francisco

Decipher AI offers an analytics agent that analyzes session replays to reveal user behavior, automatically uncover and prioritize issues, and reduce churn. It is led by a small team of ex-Googlers, including co-founders Rohan Das and Michae

Pincites

San Francisco

Pincites is an AI contract negotiation assistant embedded in Microsoft Word that helps legal teams review and redline contracts faster; a YC S23 startup with unicorn customers, it doubled revenue in Q1 2024 and is led by Sona and Mariam.

FuseAI

San Francisco

FuseAI is a Y Combinator–backed enterprise GTM automation platform building an agentic OS to automate go-to-market teams with AI agents. San Francisco-based, eight-employee startup founded by Saurav Bubber and Imogen Low, who bring Deel and

Paragon AI

San Francisco

Paragon AI (S22) provides AI-powered sales technology that extracts information from meetings, emails, and calls to automate tasks, deliver insights, and coach teams, addressing administrative burdens and incomplete CRM data; led by founder

DryMerge

San Francisco

DryMerge provides a platform to create AI agents that connect to apps and automate tasks via a chat interface, emphasizing near-perfect accuracy and deep integrations with Gmail and Salesforce; it is a small Rust/Javascript/Svelte engineeri

Tenjin

San Francisco

Tenjin provides mobile growth infrastructure that organizes, analyzes, and secures data from mobile devices and marketing channels, aiming to replace detached services with an integrated data platform. It operates with a remote-friendly tea

Gale

San Francisco

Gale disrupts the $10B immigration services market by delivering a tech-enabled, human immigration process for US H-1Bs that uses automation and AI to boost lawyers' efficiency, reduce costs, and shorten visa turnaround times for U.S. compa

Letter AI

San Francisco

Letter AI provides generative AI-powered sales enablement, unifying training, coaching, and content creation to improve win rates. Since launch, it has onboarded Lenovo and Redpanda as its first customers and secured funding from Y Combinat

Origami

San Francisco

The company builds vertical AI agents to handle sales research and develops custom AI web agents. Co-founded by Finn Mallery and Kenson Chung, who previously served as CTO of an enterprise sales platform with $1B+ revenue clients; partnersh

Lapel

San Francisco

Lapel builds data infrastructure and tools that help customer-facing teams understand every customer and act on insight at scale, pursuing hospitality at scale by unifying context and coordinating action.

Patterns

San Francisco

Patterns aims to make data analysis accessible by using natural language processing and AI to analyze data, aiming to simplify analytics and transform business intelligence, with next-gen financial analysis and AI agents for reporting; tech

ZeroEntropy

San Francisco

ZeroEntropy is a B2B software and services infrastructure company focused on AI-driven information retrieval over complex unstructured data. With a two-person founding team and Y Combinator Winter 2025 participation, it combines mathematics

AI Insurance

San Francisco

AI Insurance offers a platform for SMB insurers to run all business processes, aiming to do for SMB insurance what Salesforce did for SMB sales, targeting 10,000+ firms and $238B in admin waste, to digitize and automate claims and underwrit

RunRL

San Francisco

RunRL (X25) is a San Francisco–based reinforcement learning as a service provider delivering on-demand RL capabilities to B2B software and services infrastructure companies, operated by a three-person team led by founders Andrew Gritsevskiy

SuperTokens

San Francisco

SuperTokens develops open source authentication software for developers and organizations, aiming to offer an open-core, secure, flexible, and easy-to-use solution. It runs on premises for free, with a hosted tier, and is used by hundreds o

Social Radar

San Francisco

Social Radar is a San Francisco-based B2B software and services company with a three-person team, founded by Rohan Arora and Venkat Krishnan. It bills itself as the best way to search for posts, people, and comments across channels.

Godela

San Francisco

Godela, a San Francisco-based, three-person B2B software startup founded by Abhijit Pranav Pamarty and Cinnamon Sipper, builds AI models for engineers and scientists, including first Physics Foundation Model that learns from simulation, exp

Anglera

San Francisco

Anglera, a Y Combinator S24 company, uses AI agents to transform messy product data into structured, AI-ready listings and automate catalog management, positioning itself as infrastructure for intelligent commerce; led by Amay Aggarwal and

Surface Labs

San Francisco

Surface Labs builds an AI-powered marketing operations platform for B2B clients, generating tens of thousands of leads monthly for dozens of customers. Backed by investors and a remote team, founders include CEO Saharsh Agrawal and Arjun Sa