B2B startups in New York

Joyful Health

New York

Joyful Health provides a revenue recovery solution that combines software with an expert team to help healthcare practices reclaim lost revenue. It claims clients recover revenue worth 5-10x the company’s fees.

Abacum

New York

Abacum provides a Business Planning platform for finance teams; founded in 2020 by two former CFOs, it has raised over $100M including a June 2025 $60M Series B and serves major customers worldwide.

Shade

New York

Shade is a seed-stage startup developing the future of file storage, backed by General Catalyst, Contrary, SignalFire, and Bling, with over 50 customers including Webflow, Salesforce, the U.S. Soccer Team, and Whoop.

Humoniq

New York

YC-backed startup raised over $8 million, led by repeat entrepreneurs, building AI-native BPO solutions for travel and transport. It aims to deploy deeply integrated AI systems that understand, reason, and act to solve travel problems; base

Dealops

Brooklyn

The company builds revenue infrastructure for B2B AI firms, starting with automated deal pricing to reduce overdiscounting and boost revenue. Backed by $7M, Stripe pricing veterans lead; it counts Airwallex, Plaid, LangChain, Clay as partne

GovSignals

New York

GovSignals offers the GovCon platform, an AI solution to disrupt the government contracting market by accelerating pre-RFP intelligence, capture, proposal development, and AI knowledge management workflows for clients from small businesses

FutureClinic

New York

FutureClinic enables doctors to launch chat-based clinics and offer subscription care, creating a category focused on personal doctors via chat and aiming for patients worldwide to begin care by speaking directly to chosen doctors through t

Glimpse

New York

Glimpse provides AI services for retail brands and aims to become a suite of solutions; launched in 2024, it grew to 100 customers and raised $17 million from 8VC and Y Combinator, led by founders who built Airbnb’s product-placement networ

Highbeam

New York

Highbeam is a banking and cash management platform for goods sellers, founded by veterans of Shopify, Square, Rippling and Toast, turning banking into a profit center. It serves $1B+ GMV and gives $5M–$200M brands enterprise financial capab

Autonomy Health

New York

Autonomy Health is building the core operating system for private neurology practices to empower neurologists to launch and run autonomous clinics, aiming to revive private practice and transform neurological care in the United States.

Ergo

New York

Ergo converts unstructured conversations from Zoom, email, Slack, and phone into structured CRM data, delivering real-time, actionable insights for sales reps and managers and enabling proactive follow-ups for clients such as Rho, Delve, Wh

Glide

New York

Glide offers an embedded fintech platform that helps legacy institutions like community banks and credit unions modernize experiences; in 2023, it pivoted from a digital bank and crypto app to infrastructure services, drawing on talent from

Cotera

New York

Cotera is building an AI automation platform for businesses, initially targeting Customer Experience teams. Led by founder Tom Firth, the eight-person company has a four-person technical team with engineers in London and New York and a data

Tarsal

New York

**Tarsal** Data pipeline for your security data lake. Tarsal is a data pipeline custom built for security teams. As security data grows 25% year over year, security teams desperately need access to best-in-class data infrastructure. Tarsa

Aktos

New York

Aktos is a software company delivering debt collection workflow platforms designed to improve the credit recovery experience for agencies, doctors’ offices, and local governments; founded by seasoned leaders from Zenefits, TikTok, Meta, Lin

Rwa.xyz

New York

RWA.xyz is the leading data platform for tokenized assets, serving clients such as Goldman Sachs, J.P. Morgan, the U.S. Treasury, and the IMF. Backed by Archetype, Jump, and Solana, its team combines Silicon Valley fintech innovation with W

J2 Health

New York

J2 Health transforms how healthcare organizations design and manage provider networks, aiming to meet patients' medical and personal needs, and is backed by investors including Tiger Global and Primary Ventures, positioning networks as a cr

SellScale

New York

SellScale builds software and AI tools that empower go-to-market leaders and founders at high-growth businesses with agentic sales agents using LLMs, vector databases, and tools like prospecting, web intent, and sequencing to boost efficien

NewtonX

New York

NewtonX is an end-to-end B2B market research partner that answers tough questions via a proprietary network of verified professionals, delivering rapid, AI-enabled insights through its platform and dedicated business consultants to power mi

Avina

New York

Avina is an AI-focused sales intelligence company that helps businesses find customers and close deals by analyzing data to identify buying signals, powered by an AWS-based stack, 40+ LLMs in code, and a unified data foundation, with 25% Mo

Authzed

New York

The company provides open-source authorization solutions for planet-scale authorization, offering managed services. Backed by a $3.9M seed and $12M Series A, it fuels community growth and enterprise revenue; remote across US and Europe, aim

Factored Quality

New York

Factored Quality serves 100+ consumer goods brands, providing quality control and compliance across supply chains to help maintain standards.

Ploomber

New York

Ploomber is a New York cloud platform that helps companies deploy and scale AI apps, often called Heroku for AI. Hosted on AWS, it uses Python for open-source framework, and its founders bring AWS experience and YC Winter 2022 status.

Arpari

New York

Arpari is a seed-stage, New York-based platform that simplifies daily treasury operations for finance teams; founders include Goldman Sachs veterans and it is backed by prominent investors, serving as a system of record for large customers,

Sweetspot

New York

Sweetspot is an AI-powered, all-in-one government sales platform that helps businesses find, manage, and respond to government opportunities, lowering the barrier to government contracting. Early customers include Vannevar Labs and Flexport

Maintouch

New York

Maintouch automates the marketing services market, starting with the $150B SEO sector and targeting a $1T annual spend, aiming to be the system of action for marketing by automating labor; led by a lean team of ex-founders with proven resul

Atlas-cashflow

New York

Escargot simplifies sending physical cards by handling printing, postage, and mailing, pairing thoughtfulness with fun. It is led by Andrew Gold and Aaron Albert, who bring software and startup-exit experience from Apple, Coinbase, Ziina, a

Village Labs

New York

Helping America's businesses become employee owned

Formula Insight

New York

Help Institutional Investors manage, track & query their Excel models

RowFlow

New York

Replacing forms with AI conversations

Alter

New York

Privileged Access Management for AI Agents

Closera

New York

AI Shopping Agent for Your Ecommerce Store

Synthetic Society

New York

Synthetic Videos to Simulate Real Users

G LNK

New York

Simplifying Collaboration for Healthcare Organizations & Professionals

Tire Swing

New York

AI Compliance for Affordable Housing

Melder

New York

AI formulas and document support for Microsoft Excel

Afternoon.co

New York

Bookkeeping, compliance and tax for founders

fixa

New York

Fix your voice agents faster