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Lead the development, optimization, and validation of molecular biology methods and assays, specifically focusing on NGS sample and library preparation for cancer diagnostics. The role involves designing robust experiments, analyzing data, and collaborating across R&D and quality functions to create validated diagnostic products.
Requires a PhD in molecular life science with postdoctoral or industry experience, or equivalent depth of expertise. Candidates must have extensive experience in NGS, a strong command of experimental design (DoE), and proficiency in data analysis using Python or R.
The Origin Group Limited (TOGL (Holdings) Ltd) is the parent organisation and technical service provider to a focused portfolio of UK-based medical technology, research, and innovation companies. Organisations within the group include Origin Sciences, Ellele Health, and Biomii. Based in Granta Park, Cambridge, UK, the organisation has established, and managed, several clinical studies to collect and biobank a range of sample types, including mucus-based biospecimens using our proprietary medical device. The biobank provides a valuable source of clinical material that we use for research, method/technology development, and the creation of diagnostic assays.
Currently, our primary focuses are in the early detection of Colorectal Cancer (CRC) and pre-cancerous lesions as well as cancers of the gynaecological tract. Our motivation is to streamline diagnostic pathways, providing efficient screening, triage, treatment selection, and surveillance solutions with greater utility than existing methodologies, enabling healthcare systems to detect earlier, reduce waiting times, and minimise invasive procedures.
The Role
As a Senior Scientist in our R&D team, you will help drive the development, optimisation and validation of the molecular biology methods, assays, protocols and products that underpin our diagnostic, working in the context of cancer molecular diagnostics. This is a hands-on, predominantly laboratory-based role for someone who wants to own their science end to end – from experimental design through to validated, well-documented methods ready for downstream use.
Main duties may include:
Essential Knowledge, Skills, and Experience:
You will typically hold a PhD in molecular life science, complemented by postdoctoral and/or relevant industry experience – or offer equivalent depth of experience.
Desirable Knowledge, Skills, and Experience:
About you
Practical details
Offices: 93 SYCAMORE ROAD, BUCKINGHAMSHIRE, HP6 5EJ, GB
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