North Chicago, Illinois, United States · On-site
$125k–$237k/yr
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Skills: Biocatalysis, Synthetic Organic Chemistry, Enzyme Discovery, Directed Evolution, AI/ML Tools
North Chicago, Illinois, United States · On-site
$130k–$195k/yr
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Skills: Biocatalysis, Synthetic Organic Chemistry, Enzyme Discovery, Directed Evolution, AI/ML Tools
Chicago, Illinois, United States · Remote OK
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Skills: Territory Business Planning, Hematology/Oncology Sales, Disease State Education, Clinical Data Presentation, Account Management
Chicago, Illinois, United States · On-site
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Skills: C++, Python, Quantitative Research, Business Optimization, Data Pipeline Design
River Forest, Illinois, United States · Hybrid
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California, United States · Hybrid
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California, United States · Hybrid
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Normal, Illinois, United States · On-site
About Rivian Rivian is on a mission to keep the world adventurous forever. This goes for the emissions-free Electric Adventure Vehicles we build, and the curious, courageous souls we seek to attract. As a company, we con…
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Wheeling, Illinois, United States · On-site
$75k–$85k/yr
Location: Wheeling, IL Are you passionate about quality, precision and engineering excellence? Join our NTN Test Lab team as a Test Engineer and play a key role in ensuring the performance, and reliability of world-class…
Skills: Product Testing, Metrology, 3D CAD Software, Mechanical Aptitude, Project Management
North Chicago, Illinois, United States · On-site
$182k–$346k/yr
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Skills: Clinical Development, Artificial Intelligence, Machine Learning, Data Convergence, Translational Medicine
Northbrook, Illinois, United States · On-site
$24/hr–$26/hr
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Skills: Reaction Equipment Operation, Chemical Processing, Quality Control, Troubleshooting, SOP Adherence
Northbrook, Illinois, United States · On-site
$24/hr–$26/hr
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Northbrook, Illinois, United States · On-site
$26/hr–$29/hr
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Northbrook, Illinois, United States · Hybrid
$82k–$90k/yr
We are seeking a Product Specialist to join our Product Management team supporting the Materials & Plastics business within UL Solutions' Engineered Materials organization. This is a hybrid position based in Northbrook, …
Skills: Product Management, Business Strategy, Market Analysis, Customer Engagement, Cross-functional Collaboration
Elgin, Illinois, United States · On-site
$27/hr
Derick Dermatology (DD) is an internationally recognized and award-winning medical practice. Founded in 2006, our world class providers offer medical, surgical, and cosmetic dermatology care in state-of-the art facilitie…
Skills: Mohs Histology, Specimen Grossing, Chuck Preparation, Microtomy, Staining
Chicago, Illinois, United States · On-site
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Skills: Emergency Medicine, Soft Tissue Surgery, Endoscopy, Triage, Physical Examinations
North Chicago, Illinois, United States · On-site
$182k–$346k/yr
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Skills: GLP Regulations, GCP Regulations, Quality Assurance, Audit Management, Vendor Compliance
Galesburg, Illinois, United States · On-site
$36k–$38k/yr
The Chemistry Lab Coordinator works closely with chemistry faculty to facilitate chemistry and biochemistry lab courses, with an emphasis on introductory chemistry classes. The Lab Coordinator plays an essential role in …
Skills: Laboratory Coordination, Chemical Handling, Equipment Maintenance, Instructional Support, Grading
Loves Park, Illinois, United States · Hybrid
$150k–$155k/yr
Position Summary: The Process Engineer will make a meaningful impact on TH Foods portfolio by leading key process development and implementation initiatives that enable innovation, improve manufacturing capability, and s…
Skills: Process Development, Commercialization, Scale-up, Continuous Improvement, Project Management
Mettawa, Illinois, United States · On-site
$125k–$237k/yr
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Skills: Pharmaceutical Marketing, Strategic Planning, Budget Management, HCP Marketing, Product Launch
North Chicago, Illinois, United States • On-site
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Lead the development of biocatalytic processes for the scalable synthesis of active pharmaceutical ingredients (APIs) using enzyme discovery and directed evolution. Utilize AI/ML tools and high-throughput experimentation to optimize enzyme-catalyzed reactions and lead project teams across various modalities.
Requires a degree in organic chemistry with significant experience (6+ years for PhD) in biocatalysis and synthetic organic chemistry. Must be proficient in recombinant DNA techniques, protein expression, and the application of data science/AI/ML to chemical synthesis.
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
The Process Chemistry group is responsible for inventing and executing the chemical processes for preparing active pharmaceutical ingredients (API) to enable toxicology studies, clinical trials, and drug product development for AbbVie’s pre-clinical and clinical candidates. We create valuable intellectual property through composition of matter, chemical processes, and technology, resulting in the development of safe and cost-effective commercial manufacturing processes.
AbbVie is seeking a highly skilled and innovative Principal Research Scientist I to contribute to chemical process research and development of small molecules, peptides, antibody-drug conjugates, and other modalities via expertise in biocatalysis. The selected candidate will contribute to the development of biocatalytic processes for the scalable synthesis of active pharmaceutical ingredients (APIs), enzyme discovery, directed evolution campaigns, and application of AI/ML tools for the discovery and optimization of enzyme-catalyzed reactions. Deep expertise in biocatalysis, a strong foundation in synthetic organic chemistry, and the technical versatility to integrate modern computational and high-throughput experimentation tools into process development is required for this role.
Responsibilities:
Contribute to the setting and implementation of strategies for solving complex synthetic problems in process development, via implementation of biocatalytic methods.
Contribute to the identification and design of enzymes, application of recombinant DNA techniques, heterologous protein expression, and directed evolution methodologies to engineer biocatalysts with improved activity, selectivity, and stability in support of novel or improved synthetic transformations for API process development.
Leverage AI/ML tools, bioinformatics platforms, and high-throughput experimentation (HTE) to accelerate enzyme screening, optimization, and process development cycles.
Participate in and/or lead project teams associated with process development and characterization for small molecules, peptides, antibody-drug conjugates, and other modalities.
Connect unrelated concepts to generate new ideas and always be on the lookout for the next big win.
Author and review technical reports, regulatory documents, patents, and scientific publications, present findings at internal and external scientific forums.
Understand and adhere to corporate standards regarding GxP compliance, code of conduct, safety, and appropriate handling of materials.
Bachelor’s, Master’s, or PhD Degree in organic chemistry with typically 14+ (BS), 12+ (MS) or 6+ (PhD) years of experience.
Expertise in synthetic organic chemistry with demonstrated hands-on experience in biocatalysis, including enzyme screening, characterization, and application to synthetic transformations.
Proficiency in recombinant DNA techniques and protein expression for enzyme production and engineering.
Experience with high-throughput experimentation (HTE) platforms and data analysis workflows for rapid enzyme identification and reaction optimization.
Demonstrated ability to employ AI/ML and data science approaches to solve complex chemical synthesis problems.
Demonstrated ability in innovating new chemical and automation technologies.
Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations.
Experience in synthetic molecule process development.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Allergan is now part of AbbVie. AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @AbbVie on LinkedIn for future updates.
Offices: Allergan plc, Dublin, Coolock D17 E400, IE · Morris Corporate Center III, 400 Interpace Parkway, Parsippany, NJ 07054, US · Parkway, Marlow, England SL7 1YL, GB · 301 W Howard Ln, Austin, TX 78753, US · 8301 Mars Dr, Hewitt, TX 76712, US
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