Pasadena, California, United States · Remote OK
$225k–$262k/yr
Introduction: Xencor is a public, clinical-stage biopharmaceutical company located in the Los Angeles area (Pasadena) and in San Diego. Our focus is developing high-potential XmAb® bispecific T-cell engagers and addi…
Skills: Population PKPD Modeling, Exposure-Response Analysis, T-cell Engagers, Immunology, Rstudio
Pasadena, California, United States · Remote OK
$225k–$262k/yr
Introduction: Xencor is a public, clinical-stage biopharmaceutical company located in the Los Angeles area (Pasadena) and in San Diego. Our focus is developing high-potential XmAb® bispecific T-cell engagers and addition…
Skills: Population PKPD Modeling, Exposure-Response Analysis, T-cell Engagers, Rstudio, NonMem
Pasadena, California, United States · On-site
$106k–$127k/yr
Job Details New ideas are all around us, but only a few will change the world. That’s our focus at JPL. We ask the biggest questions, then search the universe for answers—literally. We build upon ideas that have guided g…
Skills: Integrated Master Schedule (IMS), DCMA 14-Point Assessment, Earned Value Management (EVM), Microsoft Project Server, Cost and Schedule Integration
Pasadena, California, United States · On-site
$125k–$160k/yr
About Us: BW Design Group is a fully integrated architecture, engineering, construction, system integration, and consulting firm committed to helping our clients realize their most critical goals from Strategy to Commerc…
Skills: Architectural Design, Construction Documents, Building Envelope Systems, Code Research, Revit
Pasadena, California, United States · On-site
$107k–$155k/yr
Job Summary: This position oversees the overall VDC delivery of a project from start to finish, including modeling, BIM trade coordination, and detailing deliverables by planning, directing, and tracking VDC team activit…
Skills: VDC Project Management, BIM Coordination, Navisworks, Revit, AutoCAD
Sophia SpacePasadena, California, United States · Hybrid
$150k–$230k/yr
Job Description Sophia Space is building TILE — a modular orbital data center node that flies on the Athena demonstration mission in late 2027. The TILE's Electrical Power System — solar array conditioning, battery, and …
Skills: Electrical Power Systems, Spacecraft Hardware Design, Harness Design, Battery Safety, Grounding And Bonding
Pasadena, California, United States · On-site
$60/hr–$84/hr
OVERVIEW Must be a US Person or Permanent Resident Duration - 12 month contract position with potential to be extended or converted W2 with full benefits, 9/80 Work Schedule Customer and contract specific training will b…
Skills: Power System Design, Subsystem Integration, Verification And Validation, Electrical Ground Support Equipment, Circuit Fundamentals
Pasadena, California, United States · On-site
$60/hr–$80/hr
OVERVIEW Must be a US Person or Permanent Resident Duration - 12 month contract position with potential to be extended or converted W2 with full benefits, 9/80 Work Schedule Customer and contract specific training will b…
Skills: Power Electronics, Integration And Test, Python, Circuit Debugging, EGSE Development
Pasadena, California, United States · On-site
$50/hr–$75/hr
OVERVIEW Must be a US Person or Permanent Resident Duration - 14 month contract position with potential to be extended or converted W2 with full benefits, 9/80 Work Schedule Customer and contract specific training will b…
Skills: Hvac Design, Mechanical Engineering, AutoCAD, Bluebeam, Building Codes
Pasadena, California, United States · On-site
$30/hr–$40/hr
GEA Group, founded in Germany in 1881, is a global leader in engineering solutions, serving industries such as food and beverage, pharma, dairy, and more. With over 18,000 employees worldwide and a strong U.S. presence s…
Skills: Compressor Rebuild, Compressor Inspection, Machining, Parts Cleaning, Technical Support
Pasadena, California, United States · On-site
$106k–$127k/yr
Job Details New ideas are all around us, but only a few will change the world. That’s our focus at JPL. We ask the biggest questions, then search the universe for answers—literally. We build upon ideas that have guided g…
Skills: Integrated Master Schedule (IMS), DCMA 14-Point Assessment, Earned Value Management (EVM), Microsoft Project Server, Microsoft Excel
Pasadena, California, United States · On-site
$75k–$97k/yr
Job Details New ideas are all around us, but only a few will change the world. That’s our focus at JPL. We ask the biggest questions, then search the universe for answers—literally. We build upon ideas that have guided g…
Skills: Cleanroom Maintenance, HEPA Filtration, Environmental Monitoring, ESD Products Management, Facility Interface
Pasadena, California, United States · On-site
$122k–$148k/yr
Job Details New ideas are all around us, but only a few will change the world. That’s our focus at JPL. We ask the biggest questions, then search the universe for answers—literally. We build upon ideas that have guided g…
Skills: Pressure Systems Safety, Cryogenic Engineering, ASME Boiler and Pressure Vessel Code, API Standards, Nondestructive Testing (NDT)
Pasadena, California, United States · On-site
AAMCO Transmissions is the world’s leader in transmissions and complex automotive repairs. We are expanding at a rapid rate and looking for the best of the best in the industry. We are actively seeking experienced techni…
Skills: Transmission R&R, General Automotive Repair, Automotive Diagnostics, Electrical System Repair, Mechanical Repair
Pasadena, California, United States · On-site
$212k–$265k/yr
Job Details New ideas are all around us, but only a few will change the world. That’s our focus at JPL. We ask the biggest questions, then search the universe for answers—literally. We build upon ideas that have guided g…
Skills: System Safety Engineering, Leadership, Strategic Planning, Risk Management, Project Management
Pasadena, California, United States · On-site
$26/hr–$29/hr
Job Summary: This position is responsible for providing administrative support including TAB Reports, Start-Up Reports, and Warranty Documents for the Systems Operations team. Essential Duties and Responsibilities: Manag…
Skills: Payroll Entry, Data Entry, Microsoft Excel, Microsoft Word, Gmail
Pasadena, California, United States · On-site
Job Summary: Under the direction of the Senior Manager, Finance, the Senior Financial Analyst supports financial planning, budgeting, forecasting, and reporting activities for the organization and its subsidiaries. This …
Skills: Financial Planning, Budgeting, Forecasting, Financial Modeling, Variance Analysis
Pasadena, California, United States · On-site
To provide supervised advice to the business in compliance with radiation protection legislation as well as on Class 7 Dangerous goods legislation and to ensure that all work is done to keep the risk from radiation expos…
Skills: Radiation Safety, Radiation Monitoring, Compliance, Data Analysis, Report Preparation
Pasadena, California, United States · Remote Solely
$140k–$200k/yr
The mission of Speechify is to make sure that reading is never a barrier to learning. Over 50 million people use Speechify’s text-to-speech products to turn whatever they’re reading – PDFs, books, Google Docs, news artic…
Skills: Python, Bash, Linux, Docker, Infrastructure-as-Code
Pasadena, California, United States · Remote Solely
$140k–$200k/yr
The mission of Speechify is to make sure that reading is never a barrier to learning. Over 50 million people use Speechify’s text-to-speech products to turn whatever they’re reading – PDFs, books, Google Docs, news artic…
Skills: TypeScript, Node.js, Google Cloud Platform, AWS, Azure
Pasadena, California, United States • Remote OK
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Lead the pre-clinical and clinical investigation of PKPD, safety, and efficacy relationships for novel T-cell engagers and immune-based therapeutics. Build population models to inform dose selection, support regulatory interactions, and collaborate cross-functionally to optimize dose-escalation and RP2D decisions.
Requires a Master's degree with 10+ years of experience or a PhD with 7+ years of experience in Pharmacokinetics or a related field. Must have prior experience with T-cell engagers and proficiency in modeling software such as NonMem, Monolix, or PUMAS.
Introduction:
Xencor is a public, clinical-stage biopharmaceutical company located in the Los Angeles area (Pasadena) and in San Diego. Our focus is developing high-potential XmAb® bispecific T-cell engagers and additional engineered drug candidates that leverage our differentiated technology platforms, and we are advancing our pipeline toward clinical proof-of-concept decisions. Our goal is to create high-impact therapeutics for patients with cancer and other serious diseases. More than 20 XmAb drug candidates engineered with our technology are in clinical development, and three XmAb medicines have been marketed by partners. For more information, please visit www.xencor.com. We have an excellent opportunity for a Director, Pharmacometrics & Quantitative Medicine to join our team.
This position can be hybrid with 2 days a week onsite from either our Pasadena or San Diego office or remote with candidate available during PST working hours.
Summary:
Responsible for pre-clinical and clinical investigation of pharmacokinetic vs. pharmacodynamic, safety, efficacy and other related biomarker relationships for novel T-cell engagers and immune-based therapeutics.
Primary Responsibilities:
Education/Experience/Skills:
Position requires a Master’s degree in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, Applied Mathematics, or a related discipline, plus a minimum of 10 years of related experience; a PhD with 7 years of related experience is preferred. Experience managing external service providers and CRO’s with timely delivery of clear, accurate and well-written study findings also required. Prior experience with T cell engagers is required.
Position also requires:
Occasional travel may be required, including travel between Xencor’s Pasadena and San Diego offices. Work for this position is generally performed at Xencor’s worksite and requires full-time commitment.
Expected Base Salary Range: $225,000 - $262,000
The actual salary will be based on the selected candidate’s qualifications, including skills, competencies, education and experience. Xencor offers a competitive total rewards package including 401k match, healthcare coverage, ESPP and a broad range of other benefits. In addition, this position will be eligible for an annual bonus and equity grant. For more information, please see https://xencor.com/careers/.
Americans with Disabilities Act (ADA) Statement
The Company will provide reasonable accommodations (such as a qualified sign language interpreter or other personal assistance) with the application process upon your request as required to comply with applicable laws. If you have a disability and require assistance in this application process, please contact [email protected].
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. Reasonable Accommodations may be made to enable qualified individuals with disabilities to perform the essential functions.
Equal Employment Opportunity (EEO) Statement
The Company is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender or gender identity, national origin, disability status, protected veteran status or any other characteristic protected by state or federal law.
Xencor does not accept profiles or resumes from recruiting vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by Xencor, implied or otherwise.
Proteins by Design
Designing Proteins. Delivering Medicines. Antibody and protein biotherapeutics are changing the way physicians treat autoimmune diseases, asthma, and cancer. At Xencor, we apply proprietary protein engineering technologies to develop better biotherapeutics – antibodies that target new biological mechanisms and are more potent, safer and longer lasting – to improve patient outcomes and quality of life. Our XmAb antibody engineering technology dramatically augments natural antibody immune functions while maintaining over 99.5% identity to natural antibodies. This combination of new, highly potent activities while maintaining the beneficial drug features and simplicity of natural antibodies allows us to create differentiated drug candidates with potential for breakthrough performance. The XmAb® platform has resulted in a robust pipeline of antibody product candidates, including eight in human clinical trials being developed by Xencor and by pharmaceutical partners. Xencor is also discovering biologics products that improve the performance of old antibody drugs, known as biosuperiors, to benefit patients, ease compliance and help reduce costs.
Offices: 465 N Halstead St, Suite 200, Pasadena, California 91107, US · 12770 High Bluff Drive Unit 260, San Diego, CA 92130-2077, US
Based on 142 listings with disclosed salaries, most engineering jobs in Pasadena, CA pay between $85k–$200k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 172 open engineering positions in Pasadena, CA listed on Clera. New openings are added daily as companies post roles.
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