The Role: Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and …
Skills: Technical Program Management, AI/ML Systems, LLMs, MLOps, Cloud Infrastructure
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$146k–$234k/yr
Full-time
Healthcare coverage, Voluntary benefit programs, Fitness support, Mindfulness support, Mental health support, Fertility support
Posted 6d ago
~40 hrs/week
Responsibilities
Drive the project and program management of global AI-readiness initiatives, focusing on AI security, governance frameworks, and secure development practices. Collaborate with cross-functional engineering and security teams to oversee the architecture and lifecycle of enterprise AI systems.
Requirements
Requires 8+ years of experience in Technical Program Management within AI/ML-heavy environments and deep technical knowledge of LLMs and MLOps. Must demonstrate the ability to lead complex, multi-workstream programs in highly matrixed, global environments.
Full job description
The Role:
Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.
Here’s What You’ll Do
Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting
Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process
Build processes, templates, and structure, or leverage existing ones as appropriate
Manage vendors, schedule, scope, and cost
Measure program success (or lack thereof) and risks using data and facts
Provide balanced risk remediation strategies and recommendations and drive risk mitigation
Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna
Provide clear, accurate, consistent, and timely communications
Advance good infrastructure and security practices and culture
Partner Collaboration - work with Cybersecurity, Builder Tools & Platforms, Infrastructure, Identity & Endpoint Engineering, GRC, AI Engineering, Data, Enablement/L&D, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner
Manage multiple initiatives to oversee the architecture and lifecycle of enterprise AI systems, including agent identity, tool authorization, and secure development practices; to drive governance frameworks that define permitted AI use, contextual standards, and regulatory alignment — including GxP where applicable; and to ensure end-to-end observability and monitoring of AI agents in production.
Own the operating model for AI enablement programs, including pilots, cohorts, and phased rollouts, and partner with Enablement/L&D teams to shape role‑based learning paths for AI builders
Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes
Here’s What You’ll Need (Basic Qualifications)
8+ years of Technical Program Management or Engineering Program Management in Artificial Intelligence (AI) / Machine Learning (ML) heavy environments is required
Here’s What You’ll Bring to the Table (Preferred Qualifications)
Background in software engineering, data science, or machine learning
Experience with LLM platforms, prompt engineering workflows, or AI copilots
Experience with AI development platforms, copilots, developer tooling, or MLOps concepts
Experience with responsible AI, model governance, or compliance frameworks
Experience driving structured, process-driven AI transformation initiatives.
Familiarity with tools such as Kubernetes, Airflow, MLFlow, or similar MLOps stacks
Familiarity with governed enablement models (e.g., citizen development, platform standards, golden paths)
Knowledge of security and compliance standards relevant to AI and AI-assisted engineering.
Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders
Embrace a culture of continuous service improvement and service excellence
A desire to make an impact as part of a high-growth, transformational company
Experience with GxP environments and regulatory requirements
Technical Depth: Strong understanding of AI/ML systems, including model training pipelines, LLMs, MLOps, data pipelines, and cloud infrastructure
Strong understanding of AI/ML development workflows, AI‑assisted engineering tools, or modern software development platforms
Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills
Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations
Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion
Experience improving developer productivity and building internal tools/platforms.
Ability to define metrics, analyze tradeoffs, and drive decisions with data.
Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback
Proven ability to operate in highly matrixed environments and influence without direct authority.
Excellent written and verbal communication skills, including executive‑level storytelling
Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.
Competitive healthcare, plus voluntary benefit programs to support your unique needs
A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
Family planning benefits, including fertility, adoption, and surrogacy support
Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
Savings and investments to help you plan for the future
Location-specific perks and extras
The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.

The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Our Working Model
As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.
Moderna is a smoke-free, alcohol-free, and drug-free work environment.
Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!
Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accommodations
We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com.
Export Control Notice
This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.
#LI-CK1
Our mission is to deliver the greatest possible impact to people through mRNA medicines.
Industry
Biotechnology Research
Company size
1,001-5,000 employees
Founded
2010
Headquarters
Cambridge, Massachusetts
LinkedIn followers
795,992
Total funding
$4.6B
Moderna is a pioneer and leader in the field of mRNA medicine. Through the advancement of its technology platform, Moderna is reimagining how medicines are made to transform how we treat and prevent diseases. Since its founding, Moderna's mRNA platform has enabled the development of vaccines and therapeutics across infectious diseases, cancer, rare diseases and more.
With a global team and a unique culture, driven by the company's values and mindsets, Moderna's mission is to deliver the greatest possible impact to people through mRNA medicines. For more information about Moderna, please visit modernatx.com and connect with us on X, Facebook, Instagram, YouTube and LinkedIn.
This Moderna page is not the appropriate place to report adverse events (side-effects) for any products. If you are or someone you know is experiencing a side effect, please reach out to your healthcare professional. Moderna is continuously monitoring the safety of its products. We encourage you to report any side effects directly to us at 1‑866‑MODERNA (1‑866‑663‑3762).
Please be cautious of fraudulent recruitment offers claiming to be from Moderna. Recruitment scams of this sort may originate from fake websites, social media accounts, or unsolicited communications and may ask you for personal information or request you pay them or someone else. Moderna will never ask you for payment, banking information, or anything of this sort at any stage of the recruitment process.
If you are unsure about a communication, do not provide personal information and report the activity to [email protected]. You may also report suspected fraud to the FBI’s Internet Crime Complaint Center (IC3).
Offices: 200 Technology Sq, Cambridge, Massachusetts 02139, US · 1 Upland Rd, Norwood, Massachusetts 02062, US
Biotechnology and mRNA TherapeuticsHealth CareBiotechnologyGeneticsMedicalPharmaceuticalTherapeutics
Our mission is to deliver the greatest possible impact to people through mRNA medicines.
Industry
Biotechnology Research
Company size
1,001-5,000 employees
Founded
2010
Headquarters
Cambridge, Massachusetts
LinkedIn followers
795,992
Total funding
$4.6B
Moderna is a pioneer and leader in the field of mRNA medicine. Through the advancement of its technology platform, Moderna is reimagining how medicines are made to transform how we treat and prevent diseases. Since its founding, Moderna's mRNA platform has enabled the development of vaccines and therapeutics across infectious diseases, cancer, rare diseases and more.
With a global team and a unique culture, driven by the company's values and mindsets, Moderna's mission is to deliver the greatest possible impact to people through mRNA medicines. For more information about Moderna, please visit modernatx.com and connect with us on X, Facebook, Instagram, YouTube and LinkedIn.
This Moderna page is not the appropriate place to report adverse events (side-effects) for any products. If you are or someone you know is experiencing a side effect, please reach out to your healthcare professional. Moderna is continuously monitoring the safety of its products. We encourage you to report any side effects directly to us at 1‑866‑MODERNA (1‑866‑663‑3762).
Please be cautious of fraudulent recruitment offers claiming to be from Moderna. Recruitment scams of this sort may originate from fake websites, social media accounts, or unsolicited communications and may ask you for personal information or request you pay them or someone else. Moderna will never ask you for payment, banking information, or anything of this sort at any stage of the recruitment process.
If you are unsure about a communication, do not provide personal information and report the activity to [email protected]. You may also report suspected fraud to the FBI’s Internet Crime Complaint Center (IC3).
Offices: 200 Technology Sq, Cambridge, Massachusetts 02139, US · 1 Upland Rd, Norwood, Massachusetts 02062, US
Biotechnology and mRNA TherapeuticsHealth CareBiotechnologyGeneticsMedicalPharmaceuticalTherapeutics