AI/ML startups in San Francisco Bay Area

Pickle

San Francisco

Pickle is a New York startup building an AI avatar that speaks in your voice to connect on your behalf, aiming to scale human ties in the age of AI, backed by Y Combinator, NFX, Krew Capital, and BASS Ventures.

Govini

San Francisco

Govini transforms Defense Acquisition from an outdated manual process into a software-driven strategic advantage for the United States, serving the national security community and every department of the military by enabling faster, more in

Sendbird

San Mateo

Sendbird, based in California, provides messaging solutions for apps, handling over 7 billion conversations per month for 4,000+ apps including DoorDash and Yahoo Sports. Backed by ICONIQ, SoftBank, Tiger Global, and Y Combinator, it is a l

Cuckoo Labs

San Francisco

Cuckoo Labs uses AI to break down language barriers for global teams with AI-driven language solutions. It is trusted by Snowflake, PagerDuty, Weights & Biases, and ClickHouse to enable global collaboration.

Deepgram

San Francisco

Deepgram is a foundational AI company focused on speech transcription and understanding, building AI for speech. A Y Combinator company and NVIDIA partner, it completed a $72M Series B and says it is most-funded speech AI company at its sta

SafetyKit

San Francisco

SafetyKit is a content-moderation AI company that replaces human moderators with language models, serving Character.ai, Substack, Upwork, Faire and Eventbrite. Founded by Stripe/Airbnb veterans, it uses open-source and hosted LMs, vision mo

Optifye.ai

San Francisco

It provides production management services powered by vision AI, focusing on applying vision AI to production processes.

Same

San Francisco

Same enables anyone to prompt software into existence, March 2025 mission that drew 350,000 signups and seven-figure ARR. Led by Aiden Bai and Nisarg Patel, it develops open-source Million.js and React Scan, in production at Airbnb, Robinho

Triomics

San Francisco

Triomics provides an oncology-focused AI engine, OncoLLM, that reduces the burden of manual chart review for cancer care providers and accelerates clinical trial enrollment while powering quality improvement and strategic initiatives.

Regology

Palo Alto

Regology provides an AI-driven regulatory compliance solution for enterprises, helping organizations manage complex rules with advanced technology; a leader in AI-powered regulatory intelligence aiming to simplify compliance and position it

Neon Health

San Francisco

Neon Health automates patient access workflows for pharma companies, streamlining benefit verifications, prior authorizations, financial assistance enrollment, onboarding, and adherence management to accelerate access to life-saving treatme

Powder

Redwood City

Powder builds AI agents that help financial advisors work faster, smarter, and with greater precision. Serving wealth managers handling billions in assets, Powder operates at the intersection of wealth management and AI, backed by top-tier

Partcl

San Francisco

Partcl develops the next generation of chip design automation tools powered by GPUs and AI, claiming its tools are 1000x faster than legacy options.

Camfer

San Francisco

Camfer enables engineers to use natural language for CAD tasks, building AI agents that autonomously design, source off-the-shelf parts, and generate drawings. It has Y Combinator recognition and OpenAI's o1 hackathon wins, plus a $4.8M see

Hamming AI

San Francisco

Hamming automates testing for AI voice agents, creating simulations with real conditions to ensure reliability. Led by CEO Sumanyu and CTO Marius, it uses OpenAI/Anthropic tech and has seen 8x revenue growth last month.

Sonia

San Francisco

San Francisco startup developing Sonia, a safe AI therapist designed to clinically match 99th percentile human therapist and broaden access to mental health care. A team has raised $3.5M from YC, Moonfire, Verkada, Reddit, Instacart founder

Accend

San Francisco

Accend builds AI-powered risk, compliance, and underwriting automation tools for fintechs and banks. A YC S23 graduate, it has raised $6.2M in seed funding from Adverb Ventures, YC, General Catalyst, and 645 Ventures; clients include Pleo,

Penciled

San Francisco

Penciled is a healthcare tech company building an AI-driven patient engagement agent for physical therapists to automate time-consuming front-desk tasks; part of Y Combinator's Winter 2024 cohort and deployed across multiple PT chains natio

Ocular AI

San Francisco

Ocular AI offers an annotation engine for Generative AI, Computer Vision, and Enterprise AI, with Ocular Foundry for labeling, versioning, and deploying data, and Ocular Bolt leveraging a global expert workforce to accelerate labeling at sc

Olive

San Francisco

Olive enables companies to create internal tools by describing their needs in natural language, positioning itself as the fastest way to create internal tools. It has raised a $2.1 million seed round and is scaling its team.

AgileMD

San Francisco

AgileMD develops a cloud-based hospital decision-support platform used by thousands of physicians across hospitals and clinics in the United States, headquartered in San Francisco, delivering care decisions grounded in current medical knowl

Lamar Health

San Francisco

Lamar Health leverages data science and AI to scale staff expertise for specialty medication workflows and automate patient paperwork, building infrastructure that connects care teams, clinics, and patients.

Vly.ai

San Francisco

vly.ai is building an AI full-stack development platform that can architect, build, deploy, and iterate on complete applications autonomously, aiming to replace most full-stack work within a year and competing with Replit, Lovable, and bolt

Morph

San Francisco

MorphLLM develops Fast Apply models for code editing AI, claiming the fastest LLM code-editing inference engine, delivering 10,500 tokens per second per request on Nvidia hardware. Its stack enables high-throughput AI workflows for coding a

Intercept

San Francisco

Intercept uses AI to automate auditing of retailer and distributor fees in the CPG sector, disputing invalid charges to recover money for brands and strengthen trust in transactions among brands, distributors, and retailers in a multi-trill

Andy AI

San Francisco

Andy AI is a seed-stage startup automating clinical documentation for home-visit nurses by turning visit audio into completed forms, cutting the 90-minute process and improving care for older adults while addressing America's nursing shorta

Orchids

San Francisco

Orchids is an AI app and site builder, one of the fastest-growing in its market, leveraging cutting-edge AI to transform how apps and websites are built. It aspires to be the last tool people need to deploy apps and sites.

Revamp

San Francisco

Revamp AI is a YC-backed retention-marketing startup for ecommerce brands, aiming to redefine the space. It has seven-figure ARR, rapid growth, and a client base including Dollar Shave Club, Fellow, Outdoor Voices, and Neuro, with plans for

Empathic Labs

San Francisco

San Francisco-based, engineering-first company building AI conversations that feel like real people, with real-time, native integration in FaceTime and iMessage. Backed by BoxGroup and led by a Thiel Fellow and YC alum who recently sold his

April

San Francisco

April is an AI Executive Assistant for email and calendar that is voice-first and productivity-obsessed, backed by Y Combinator; it launched in August and has shown traction as it grows, aiming to give every busy professional the assistant

Planbase

San Francisco

Planbase is a flexible AI-powered platform that embeds intelligence into operations, tailoring to each workflow to boost speed and accuracy; it serves healthcare organizations touching 100M+ patients, including $500M+ revenue leaders, with

Meridian

San Francisco

The company catalyzes the next generation of consumer experiences by redefining how people interact with products and services, driving innovation in everyday engagement and shaping how brands are experienced in modern markets.

Ohm

San Francisco

Ohm is a San Francisco-based AI-first company applying AI to battery research, validation, and manufacturing workflows. Backed by Y Combinator and other investors, it leverages a lean, multidisciplinary team of engineers, creatives, and PhD

Kalos

San Francisco

Kalos is an early-stage, high-growth startup in San Francisco, currently in stealth mode, that has built Blue, an AI agent.

Domu Technology Inc. (YC S24)

San Francisco

Domu Technology Inc. automates debt-collection calls for banks and insurers, serving six Fortune 500s and major firms including MetLife, BBVA, and BNP Paribas Cardif. A YC alum with a female-led team, it reduces costs and improves recovery

Cua

San Francisco

Cua builds infrastructure for general AI agents to safely use computers and apps. It offers an open-source framework and cloud sandboxed container platform, a seed round, 9k+ GitHub stars in four months, and a research-backed blueprint for

Trellis AI

San Francisco

Trellis provides an AI agent that automates healthcare administrative workflows—such as intake, prior authorizations, and appeals—positioning itself as a solutions-focused partner to increase provider revenue while reducing administrative b

Chima

San Francisco

Chima helps leading institutions customize and scale generative AI by integrating and analyzing private and public data to privately leverage commercial LLMs; it builds infrastructure for enterprises to customize LLMs and automate functions