AI/ML startups in San Francisco Bay Area

Outset

San Francisco

Outset, a Y Combinator–backed startup, uses AI and ChatGPT to conduct in-depth qualitative interviews at scale, aiming to revolutionize qualitative research and deliver rich, scalable insights through innovative research tooling.

MangoDesk

San Francisco

Creates frontier data and environments to advance AI, bridging AI with the $5T knowledge-work economy and accelerating AI capabilities and adoption in knowledge work.

AthenaHQ

San Francisco

AthenaHQ provides an AI Search platform that helps global brands improve visibility, discoverability, and branding. It counts Coinbase, SoFi, and Twilio among its customers and serves over 200 clients with more than $2M ARR, underscoring ra

Cekura

San Francisco

Cekura is a Y Combinator–backed startup redefining AI voice agent reliability through testing and monitoring. Founded by IIT Bombay alumni with ETH Zurich credentials and high-stakes trading experience, it guarantees dependable performance,

Colare

San Francisco

Colare is an end-to-end hiring platform for hardtech teams in automotive, aerospace, energy, and defense. Its AI-powered simulations replicate real engineering workflows—from CAD to systems problem solving—to evaluate talent, with stack-ran

Martin

Mountain View

Meet Martin, your AI butler. Martin builds a personal relationship with you over time and understands what matters most. Speak with Martin in our app, text him, or email him. Martin can get to know you, see your calendar and inbox, and proa

GovDash

San Francisco

GovDash enables businesses to win and deliver government contracts that advance American interests. Its customers won over $5B in government contracts in 2025, and GovDash has raised $42M in funding.

Poka Labs

San Francisco

Poka Labs, a San Francisco-based startup founded in 2023, builds AI agents that automate commercial operations for chemical manufacturers, led by Andrew Bass and Malay Shah; it is backed by Y Combinator, Flybridge, Pioneer Fund, and Beat Ve

Vantara

San Francisco

Vantara positions itself as an AI product engineer that monitors user sessions and feedback from support, sales, and channels, identifies patterns, prioritizes what to build, and enables PRs and A/B tests to close the loop between user inpu

Runway

San Francisco

Runway is a collaborative business planning platform that replaces spreadsheets with a modern planning solution, democratizing planning across the organization. Its customers include AngelList, Superhuman, ConvertKit, Lambda Labs, and Sandb

Scale AI

San Francisco

Scale AI provides data-centric infrastructure to accelerate AI development, helping organizations build strong AI models and derive business insights and operational efficiency; serving customers across tech, government, and enterprise, inc

Confident AI

San Francisco

Confident AI is the leading LLM evaluation platform behind the open-source DeepEval framework; its cloud product brings DeepEval to enterprises, backed by 600k+ monthly downloads, 5.3k+ GitHub stars, 40 million evaluations, and hundreds of

Opal Security

San Francisco

Opal provides enterprise identity and access management solutions. It is based in New York City and San Francisco and backed by Greylock, Battery Ventures, and Silicon Valley CISO Investments, serving hypergrowth startups and Fortune 500 co

TrueClaim

San Francisco

TrueClaim provides an AI-enabled platform for health plans, focused on advancing health-plan technology and modern operations.

Rulebase

San Francisco

Rulebase delivers visibility and confidence to modern support teams, helping them understand and improve the customer experience in real time. Its technology stack includes Python, React, and Electron JS.

InspectMind AI

San Francisco

InspectMind AI delivers AI-powered documentation and reporting tools for construction and design professionals, simplifying paperwork and streamlining on-site workflows to help workers spend less time at a desk and more time building.

Sylvan Labs

San Francisco

Sylvan Labs specializes in post-sales enablement for enterprise software, aiming to become the category-defining platform and a billion-dollar business by product- and GTM-led growth, not headcount. It pursues expansion through private equi

Helium

San Francisco

Helium automatically generates and tests paywalls to improve app conversion. Backed by Y Combinator, Google, and leaders from OpenAI and Uber, the company is positioned in the paywall automation space for apps.

Hadrius

San Francisco

Hadrius automates and consolidates securities compliance for investment firms, serving over 500 institutions and more than $5 trillion AUM. A YC W23 alum with over $10M ARR, it’s described as fastest-growing company in its space and an emer

Luminade

San Francisco

Founded by Sriram (ex-Luminade) and Mikhail (ex-Google, four-time competitive skydiving world champion); the two-person team builds a conversational voice layer for work that delivers actions in-chat, with ownership over product direction a

Resonate AI

San Francisco

An AI-driven platform that helps healthcare practices capture new patients by converting missed calls into patient inquiries, led by a founder with 10+ years of AI experience and five patents who previously built 0-to-1 ventures at Microsof

LedgerUp

San Francisco

LedgerUp is an AI-driven operations teammate for billing and accounts receivable that automates contract-to-cash workflows, reducing busywork for teams and driving growth.

Nexus Intelligence

San Francisco

An a16z-backed software startup building AI-enabled industrial automation systems for Fortune 100 customers across automotive, food, energy, and other sectors, aiming to become the platform for developing and deploying modern industrial aut

Inductive Bio

San Francisco

Inductive Bio uses data, machine learning, software, and domain expertise to rapidly solve ADMET problems with speed and precision, streamlining ADMET workflows as a focused provider in the ADMET problem space.

Greptile

San Francisco

Greptile, a San Francisco AI tooling startup with a six-person team, builds an AI expert on codebases accessible via an API, serving 1,000 software teams; raised $5.3M from Y Combinator, Initialized Capital, SV Angel, and Paul Graham, with

LlamaIndex

San Francisco

LlamaIndex offers an open-source framework that lets developers build agents to parse, extract insights, and act on enterprise documents, reasoning over data and scaling for production. It has 4M+ monthly downloads and 200M+ documents proce

Mage AI

Santa Clara

Mage is a modular workflow system that executes executable blocks to deliver reliable, relevant, and timely AI-ready data outputs; its tractable, compositional, and adaptive blocks enable teams to manage and update data pipelines as needs e

Speakeasy

San Francisco

Speakeasy is a developer platform for building and deploying agent tools as hosted MCPs, serving startups to Fortune 500s including LaunchDarkly, Fivetran, and Verizon; it emphasizes open development, a GitHub presence, and rapid team growt

LiteLLM

San Francisco

LiteLLM develops open-source developer tooling for the AI software space, enabling access to multiple LLM APIs. It has raised $1.6M in seed funding from Y Combinator, Gravity Fund, and Pioneer Fund, and reports $7M+ ARR while remaining mean

CommodityAI

San Francisco

CommodityAI is a San Francisco-based AI company serving the commodities industry, founded by former commodity traders and operators with deep industry expertise. Backed by Y Combinator and Rebel Fund, it aims to build intelligence at the fo

Forge

San Francisco

Forge automates complex manual processes for the world’s largest enterprises and advances human computer interaction. Backed by Founders Fund and OpenAI, it operates globally, powering Fortune 500 workflows with 98%+ quality across half a m

PlayAI

Mountain View

**Introduction** At [PlayHT](https://play.ht/), our vision is to redefine human interactions with AI agents. Whether it’s for customer support or sales calls, AI tutors, or bringing Gaming NPCs to life, our goal is to revolutionize the way

Chroma

San Francisco

Chroma provides data infrastructure for AI, aiming to accelerate useful and creative AI applications, and positions itself as the leading retrieval solution trusted by developers worldwide.

Two Dots

San Francisco

Two Dots uses AI to reinvent consumer underwriting, starting with residential real estate. It harnesses data in consumer documents to improve lending decisions, pairing its underwriting agent with advanced document and identity anti-fraud c

OpenBlock

San Francisco

OpenBlock builds CLI coding agents; its OB-1 ranked #1 on Terminal Bench ahead of Claude Code and Codex highlights leadership in developer tooling and its aim to empower individuals and teams to create and innovate in software development f

Parahelp

San Francisco

Parahelp offers an AI support agent for fast-moving software companies, designed to automate complex support tickets end-to-end and deployable in one day without engineers. With a five-person, founder-heavy team and rapid growth, it is seek

Mach9

San Francisco

Mach9, founded in 2021 in San Francisco, is a geospatial technology company that automates detection and analysis of urban features for transportation planning, turning geospatial data into actionable insights via machine learning and compu

Delphi

San Francisco

Delphi aims to amplify human wisdom—personalized, discoverable, and preservable—while scaling brilliance across generations. It has tripled revenue, users, and Delphi interactions in six months, backed by Sequoia Capital, Founders Fund, Abs

Dynamo AI

San Francisco

Dynamo offers end-to-end privacy, security, and compliance solutions to help organizations prepare for emerging AI regulations and productionize AI with confidence, enabling deployments aligned with evolving rules.

Evidently

San Francisco

Evidently is a Clinical Data Intelligence platform built on 12 years of advanced research in Machine Reading and Knowledge Graph, aiming to dramatically improve the efficiency and effectiveness of clinical data workflows.