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$168k–$318k/yr
Full-time
postgraduate degree
Flexible hours, Vacation account, Digital learning, Performance and talent development, Leadership development, Apprenticeships
Posted 13h ago
Apply by Dec 31
~40 hrs/week
Responsibilities
The Senior Director will lead clinical trial design and execution from early exploratory studies through late-stage development and regulatory approval. They will also serve as a Program Lead to guide core teams, ensure patient safety, and manage medical aspects of clinical portfolios.
Requirements
Candidates must hold an M.D. degree with a robust scientific background in Immuno-Oncology or Oncology. Extensive experience leading clinical development programs across Phases I–III and interacting with global health authorities like the FDA and EMA is required.
Full job description
Munich, Germany; London, United Kingdom; Mainz, Germany | full time | Job ID: 11648
About the Role
As a (Senior) Director of Clinical Development at BioNTech, you will collaborate closely with the VP of Clinical Development to drive innovative strategies for assigned programs. In this pivotal role, you will oversee the design and execution of clinical trials across all phases, ensuring data integrity, patient safety, and regulatory approval. Leveraging your deep expertise in Immuno-Oncology and Oncology, you will lead matrix teams to deliver impactful results while guiding decisions with scientific rigor and medical insight. Join us to shape the future of medicine through cutting-edge research and development.
Your Contribution
Lead clinical trial design to develop plans for new compounds from early exploratory studies through late-stage development and regulatory approval.
Collaborate with the VP to operationalize clinical strategies for assigned portfolios and ensure alignment across functions.
Serve as Program Lead, guiding core teams, driving program strategy, and preparing submission processes.
Ensure patient safety by overseeing medical aspects of studies, conducting risk-benefit assessments, and addressing medical queries.
Innovate in trial design, leveraging digital endpoints and real-world evidence to enhance study outcomes.
Develop key clinical documents, including Investigator’s Brochures, NDAs, and high-quality Clinical Study Reports.
Build strong relationships with external stakeholders while representing the team in governance meetings.
A Good Match
M.D. degree with a robust scientific and clinical background in Immuno-Oncology or Oncology.
Extensive experience leading clinical development programs across Phases I–III, including NDA submissions.
Expertise in advanced clinical study designs, companion diagnostics for patient selection, translational modeling, biostatistics, and confirmatory Phase III trial design.
Proven experience interacting globally with health authorities (e.g., EMA, FDA), with successful registration being advantageous.
Strong medical acumen in monitoring safety/efficacy data and managing patient-centric drug development processes.
Exceptional leadership skills to mentor teams while accelerating capabilities through situational management styles. BioNTech offers a collaborative environment where innovation meets purpose. If you are passionate about advancing therapies that make a difference in patients' lives, we invite you to join our mission-driven team.
Expected Pay Range: $168,100-$318,300 plus benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). *Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.
Your Benefits:
It's our priority to support you:
Your flexibility: flexible hours | vacation account
Your growth: Digital Learning | Performance & talent development | leadership development | Apprenticeships | LinkedIn Learning
Your value: Your voice at the table | Culture on an equal footing | Opportunities to shape & impact | Support for your full potential
Your health and lifestyle: Company bike
Your mobility: Job ticket | Deutschlandticket
Your life phases: Employer-funded pension | Childcare
Apply now - We look forward to your application!
Apply to our Munich, Germany; London, United Kingdom; Mainz, Germanylocation by sending us your documents via our online form. For any questions, contact our talent acquisition team on: + 49 (0) 6131-9084-1291 (Monday-Friday from 1 PM to 3 PM CET).
Job ID 11648 (please always specify if you have any questions)
By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.
Our vision is to harness the power of the immune system to develop novel therapies against cancer & infectious diseases.
Industry
Biotechnology Research
Company size
1,001-5,000 employees
Founded
2008
Headquarters
Mainz, Rhineland-Palatinate
LinkedIn followers
300,524
Total funding
$2.0B
Biopharmaceutical New Technologies (BioNTech) is a global biotechnology company aspiring to translate science into survival by developing new immunotherapies utilizing the full potential of the immune system to fight cancer and infectious diseases.
BioNTech is headquartered in Mainz, Germany, and operates globally with almost 7.000 pioneers. Our work is powered by one mission: Improving the health of people worldwide. We believe that scientific rigor and passion are the driving forces that are essential for innovative progress.
BioNTech was founded in 2008 by scientists and physicians to translate science into survival by combining fundamental research and operational excellence. At BioNTech, we have been conducting fundamental research of mRNA technologies in the field of individualized cancer medicine for more than a decade. Some of our colleagues, including our co-founders, have been researching and developing mRNA-based vaccines for more than 25 years.
Ready to join us on this journey? Explore the opportunities and become part of a team that aspires to turn bold ideas into real-world solutions: https://www.biontech.com/int/en/home/careers.html
🔗 Privacy Statement: https://www.biontech.com/int/en/home/data-privacy-statement.html
🔗 Imprint: https://www.biontech.com/int/en/home/imprint.html
Offices: An der Goldgrube 12, Mainz, Rhineland-Palatinate 55131, DE · Vollmersbachstraße 66, Idar-Oberstein, Rhineland-Palatinate 55743, DE · Vollmerstr. 5, Berlin, Berlin 12489, DE · Am Klopferspitz 19a, Planegg, Bavaria 82152, DE · Forstenrieder Str. 8-14, Neuried, Bavaria 82061, DE
BiotechnologyIndividualized cancer medicinePatient-specific immunotherapymRNA therapeuticsCell therapyAntibody therapeuticsSmall molecule immunomodulatorsTailored therapeuticsImmunotherapyOncology
How many Science & Research jobs are open in Mainz, Germany right now?
There are currently 78 open science & research positions in Mainz, Germany listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Science & Research roles in Mainz, Germany?
Companies currently hiring include VCU Department of Health Administration, BioNTech SE, OHB SE, Fraunhofer IGD, IVC Evidensia DACH, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Science & Research jobs in Mainz, Germany?
Yes — 20 of the 78 open science & research positions offer remote or hybrid work (1 remote, 19 hybrid).
How do I apply for Science & Research jobs in Mainz, Germany?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.