At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less in…
Skills: Process Engineering, API Manufacturing, Chemical Synthesis, Crystallization, Filtration
PM Group
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MSL Engineering Ltd.
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Geel, Flanders, Belgium · On-site
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MSL Engineering Ltd.
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Geel, Flanders, Belgium · On-site
Mid level
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MSL Engineering Ltd.
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Geel, Flanders, Belgium · On-site
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Turner & Townsend
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Geel, Flanders, Belgium · On-site
Senior
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Senior Manager, Business Development, Clinical Solutions - EMEA
Geel, Flanders, Belgium · Remote OK
Senior+$8.0B raised
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Beschrijving van het bedrijf From the inception of a new client portfolio of projects through to completion and beyond, Turner & Townsend helps to deliver the outcomes that matter through transformational programs coveri…
The Senior Principal Engineer will lead technical strategy and early-phase process design for synthetic drug substance manufacturing across global capital projects. They will provide domain expertise in API unit operations while driving standardization, process safety, and the adoption of digital manufacturing solutions.
Requirements
Candidates must hold at least a Master’s degree in Engineering or Pharmaceutical Sciences and possess over 10 years of experience in API manufacturing. Strong expertise in cGMP environments, process scale-up, and multi-functional team leadership is required.
Full job description
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.
As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.
Job Function:
Supply Chain Engineering
Job Sub Function:
Process Engineering
Job Category:
Scientific/Technology
All Job Posting Locations:
Geel, Antwerp, Belgium
Job Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way!
We are searching for the best talent for a Senior Principal Engineer, Process Engineering to join our Team! This is an onsite/hybrid role.
Please note that this role is available across multiple countries and may be posted under different requisition numbers to align with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s):
Belgium - Requisition Number: R-071729
Athens, GA, USA - Requisition Number: R-075187
Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission.
Position Summary
As the GET PE – Synthetics Drug Substance (API) Manufacturing Senior Principal Engineer, you will lead early design inputs and technical strategy for synthetic drug substance (API) manufacturing processes within strategic capital projects, network studies, and technology platforms across IMSC. You will provide technical expertise in synthetics API unit operations including chemical reaction, phase separations, distillation/solvent swap, crystallization/precipitation, filtration/centrifugation, drying, milling, blending, etc, while supporting solving and optimization activities at internal and external manufacturing sites.
Joining our global engineering group, you will collaborate with high‑performing, multi-functional teams across multiple sites and functions. This role offers a dynamic and inspiring work environment with significant opportunities to influence API technology direction, standardization, and capability building across the network.
Responsibilities and impact you will have:
Lead the intake, scoping, prioritization, and resolution of synthetics drug substance (API) manufacturing technical requests across global sites
Lead and influence early‑phase process design and act as domain expert for synthetics API processes, from technology and unit operation selection through scope definition and capital and schedule development
Provide technical expertise in critical API unit operations and enabling technologies (e.g., hazardous chemistry, reactions, crystallization, filtration/centrifugation, drying, and particle engineering), with a strong emphasis on product quality, process safety, and robustness
Ensure robust, fit‑for‑purpose process design while promoting standardization and platform approaches (e.g., common reactor trains, filtration/drying trains, solvent recovery concepts) where they make valuable contributions
Ensure API cGMP standards are applied consistently and proactively assess emerging regulatory expectations and industry trends to keep API manufacturing solutions inspection‑ready and compliant
Drive the adoption of digital and data‑enabled solutions for API manufacturing, including real‑time monitoring, advanced process control, advanced data analytics, model and simulation, and smart manufacturing use cases where they improve reliability and performance
Provide expert input and alignment on key process equipment, and technology selection decisions for API manufacturing (e.g., reactors, filters/centrifuges, dryers, contained transfer, solvent recovery, CIP/SIP where applicable)
Actively collaborate with other functions such as R&D/CMC, MSAT, Quality, EHS, and Operations leads across synthetic API sites to enable reliable technical solutions and fast decision making
Find opportunities for harmonization, shared solutions, and best‑practice exchange across the network (e.g., containment standards, process safety approaches, cleaning strategies, etc)
Foster a culture of collaboration to reduce duplication, accelerate implementation, and improve speed‑to‑market for API process and equipment solutions
Maintain strong connections with industry experts and external networks (e.g., ISPE) to bring innovative API manufacturing and particle/solid‑state solutions into the organization
Ensure alignment with enterprise strategies, API GMP requirements (e.g., ICH Q7 as applicable), and technology roadmaps
Collaborate with External Manufacturing teams to prioritize support and resolve issues for high‑impact programs, including API CMOs, intermediates, and critical raw material processes
Qualifications
Education:
Minimum of a Master’s degree or equivalent experience in Engineering, Pharmaceutical Sciences, or a related technical field is required
Experience and Skills:
Required:
Minimum 10 years of relevant experience in synthetics drug substance (API) manufacturing within pharmaceutical (or closely related) manufacturing environments, with strong knowledge of chemical synthesis and API isolation/purification unit operations
Demonstrated expertise in API purification and solid‑state/particle engineering, including crystallization, filtration/centrifugation, drying, milling, and the impact of these steps on quality attributes (e.g., polymorph form, PSD, residual solvents, impurities)
Proven experience with API scale‑up, technology transfer, and process fixing across pilot to commercial scale, including understanding of reactor systems, solvent handling, and process analytical/controls as applicable
Strong understanding of cGMP environments and regulatory expectations for API manufacturing across multiple end‑use modalities (e.g., APIs for OSD and sterile/low‑bioburden drug products), including data integrity and documentation practices. Experience with process safety (e.g., thermal hazard evaluation) and containment for potent compounds is a plus
Proven track record of leading multi-functional teams and influencing technical decisions in complex, global organizations
Digital mentality with experience employing manufacturing data and systems (e.g., PI/data historians) to enable continuous improvement in API operations and adoption of smart manufacturing
Ability to support early‑phase design through detailed design of API manufacturing equipment and facilities (e.g., reactors, centrifuges/filters, dryers, milling, contained transfer, solvent recovery, and supporting utilities)
Proficiency in written and spoken English; additional languages (Dutch, Spanish, Italian) are an advantage
Willingness to travel up to 25% domestically and internationally
Preferred:
Experience with inherently safe containment design for potent materials, including contained charging/transfer, dust control, and exposure mitigation
Strong customer management and communication skills, with the ability to influence across sites, functions, and external partners
Strategic perspective combined with hands‑on technical capability
Intellectual curiosity to challenge the status quo, influence without authority, and cultivate an inclusive and collaborative culture
Required Skills:
Preferred Skills:
Agile Decision Making, Coaching, Consulting, Corrective and Preventive Action (CAPA), Crisis Management, Cross-Functional Collaboration, Disruptive Innovations, Emerging Technologies, Industrial Hygiene, Lean Supply Chain Management, Process Control, Process Engineering, Product Costing, Program Management, Project Schedule, Science, Technology, Engineering, and Math (STEM) Application, Tactical Planning, Technical Credibility, Technical Research
The anticipated base pay range for this position is:
€96,000.00 - €165,025.00
Benefits:
In addition to base pay, we offer the following benefits: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location’s eligible dependents - can participate in several insurance plans. For more information, visit Employee benefits | Supporting well-being & career growth | Johnson & Johnson Careers.
This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.
At Johnson & Johnson Innovative Medicine, we innovate with purpose, to lead where medicine is going. The experiences of patients around the world inform and inspire our science-based innovations, which continue to change and save lives. Applying rigorous science with compassion, we confidently address the most complex diseases of our time and develop the potential medicines of tomorrow. We are continuously working to develop treatments, aspiring to find cures, pioneering the path from lab to life, and championing patients every step of the way. https://bit.ly/3reuMvK
Health CareBiotechnologyMedicalManufacturingPharmaceutical
How many Management & Leadership jobs are open in Geel, Belgium right now?
There are currently 25 open management & leadership positions in Geel, Belgium listed on Clera. New openings are added daily as companies post roles.
Which companies are hiring for Management & Leadership roles in Geel, Belgium?
Companies currently hiring include PM Group, Turner & Townsend, Johnson & Johnson Innovative Medicine, MSL Engineering Ltd., Schwarz IT KG, among others. Browse the listings above to see every active employer.
Are there remote or hybrid Management & Leadership jobs in Geel, Belgium?
Yes — 7 of the 25 open management & leadership positions offer remote or hybrid work (4 remote, 3 hybrid).
How do I apply for Management & Leadership jobs in Geel, Belgium?
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.