South San Francisco, California, United States · On-site
$100k–$107k/yr
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more t…
Skills: High-Plex Imaging, Computational Image Analysis, Machine Learning, Python, Single-Cell Genomics
South San Francisco, California, United States · On-site
$160k–$185k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) ORIC-…
Skills: Regulatory Submissions, Strategic Planning, Project Management, Clinical-Regulatory Writing, Cross-functional Collaboration
South San Francisco, California, United States · On-site
Since 1984, Larkin Street Youth Services has helped more than 75,000 young adults in San Francisco with outreach, shelter, housing, education, employment, healthcare, and other services. Today, Larkin Street Youth Servic…
Skills: Case Management, Crisis Intervention, Trauma Informed Care, Motivational Interviewing, Harm Reduction
South San Francisco, California, United States · Hybrid
$100k–$120k/yr
Spirair, a venture capital-backed medical device company, was co-founded by two Stanford Biodesign and Innovation fellows with a shared interest in optimizing outcomes and patient experience through innovation solutions.…
Skills: SolidWorks, Product Design, Design Control, Verification Testing, Documentation
South San Francisco, California, United States · Hybrid
$110k–$209k/yr
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a r…
Skills: SDTM Programming, CDISC Standards, ADaM Mapping, Clinical Data Standards, Regulatory Submissions
South San Francisco, California, United States · On-site
$110k–$138k/yr
About Xaira Therapeutics Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and a…
Skills: Immune Cell Isolation, Flow Cytometry, Functional Assays, T Cell Activation, Cytokine Profiling
South San Francisco, California, United States · On-site
$220k–$275k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) rinzi…
Skills: Medical Affairs Strategy, Oncology, Launch Readiness, KOL Relationship Management, Evidence Generation
South San Francisco, California, United States · On-site
$220k–$300k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) ORIC-…
Skills: CMC Regulatory Strategy, Technical Writing, Small Molecules, eCTD Structure, IND/NDA/MAA Submissions
South San Francisco, California, United States · On-site
$150k–$180k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) rinzi…
Skills: Analytical Method Development, Product Characterization, UHPLC, GC-MS, LC-MS
South San Francisco, California, United States · On-site
$150k–$180k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) rinzi…
Skills: Analytical Method Development, Product Characterization, UHPLC, GC-MS, LC-MS
South San Francisco, California, United States · On-site
$175k–$200k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) ORIC-…
Skills: Process Chemistry, Organic Chemistry, Scale-up, Tech Transfer, Analytical Tools
South San Francisco, California, United States · On-site
$175k–$200k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) ORIC-…
Skills: Process Chemistry, Organic Chemistry, Scale-up, Tech Transfer, Analytical Tools
South San Francisco, California, United States · On-site
$210k–$260k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) rinzi…
Skills: CMC Project Management, Budget Planning, CDMO Management, Cross-functional Leadership, Regulatory Filings
South San Francisco, California, United States · On-site
$210k–$260k/yr
Company Description ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients’ lives by Overcoming Resistance In Cancer. ORIC’s clinical stage product candidates include (1) rinzi…
Skills: CMC Project Management, Cross-Functional Leadership, Budget Planning, Financial Forecasting, CDMO Management
South San Francisco, California, United States · On-site
$100k–$186k/yr
We advance science so that we all have more time with the people we love. Genentech's Translational Medicine OMNI (TM OMNI) Department supports the entire R&D portfolio of novel therapies across Ophthalmology, Metabolism…
Skills: Proteomics, Transcriptomics, Simoa, NULISA, In Vitro Human Cell Models
South San Francisco, California, United States · Hybrid
$177k–$329k/yr
Why Genentech We're passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly pursuing…
Skills: Generative AI, Agentic Design, RAG Architecture, Vector Databases, Graph Databases
South San Francisco, California, United States · Hybrid
$129k–$239k/yr
Why Genentech We’re passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly p…
Skills: Omnichannel Marketing, Customer Insights, Content Creation, Campaign Execution, Market Positioning
South San Francisco, California, United States · On-site
$102k–$190k/yr
Pharma Partnering Finance - Asset & Alliance Management FEP Why Genentech We’re passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a cul…
Skills: Financial Forecasting, Monthly Closing, Financial Reporting, Compliance, Financial Modeling
South San Francisco, California, United States · On-site
$61k–$113k/yr
This role is a valuable part of our Campus Amenities and Services team, which is committed to achieving our mission of providing a world-class workspace environment that enables our employees to focus on delivering medic…
Skills: Customer Service, Visitor Management, Microsoft Office Suite, Google Suite, Interpersonal Communication
South San Francisco, California, United States · Hybrid
$233k–$272k/yr
Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients…
Skills: Pricing Strategy, Contracting, Market Access Analytics, Financial Analysis, B2B Negotiations
South San Francisco, California, United States • On-site
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Develop high-plex imaging assays and computational methods to capture rich measurements of cellular states. Design and execute large-scale compound screens across diverse model systems to accelerate drug discovery.
Requires a Ph.D. in a quantitative biological field with a proven track record of first-author publications. Must possess strong hands-on expertise in microscopy and fluency in Python for image analysis and machine learning.
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech.
A Postdoctoral Fellow position is available for a highly motivated and independent scientist to pioneer high-throughput platforms that reveal compound effects across diverse model systems and accelerate the path from molecule to medicine. The vision for this role is to push image-based profiling well beyond what is possible today—developing the experimental and computational methods to capture far richer measurements of cellular state and to extend compound screening across a much broader range of model systems than is currently feasible.
This is a hands-on position for a scientist who is energized by developing new assays at the bench and who is just as drawn to reasoning about the analytical and AI methods needed to interpret the resulting data. You will join a collaborative, cross-disciplinary environment and will have the opportunity to contribute to high-impact scientific publications.
The Opportunity:
High-Plex Assay Development: Develop and optimize high-plex imaging assays that capture rich, multiplexed readouts of cell state and morphology.
Computational Methods: Develop computational approaches that expand the information extracted from each sample and improve the efficiency and quality of imaging-based measurements.
Large-Scale Screening: Design and execute large-scale compound screens across diverse, disease-relevant model systems, generating systematic, multimodal readouts of cellular response.
Data-Driven Discovery: Apply single-cell and multi-omics style analyses to build maps of perturbation relationships and to prioritize the most promising compounds for a given function or activity.
Automation & Scale: Leverage laboratory automation and high-throughput workflows to iteratively design, run, and learn from screens at scale.
Collaborative Research: Collaborate productively with experimental and computational scientists across departments, present your work to project teams, and contribute to high-impact scientific publications.
Professional Development: Join the Genentech postdoctoral training program, which provides an outstanding environment and the opportunity to pursue fundamental scientific questions while building methods that drive breakthrough discoveries in drug development.
Who You Are:
Ph.D. with a proven track record of excellence in single-cell genomics, imaging, bioengineering, biophysics, quantitative biology, or a related field, with hands-on experimental expertise.
Must have advanced at least one key research project as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal.
Strong hands-on experience in microscopy and quantitative imaging; experience with multiplexed, high-content, or optical pooled screening approaches is a plus.
Computational expertise spanning image analysis and machine learning, with a track record of developing or adapting methods and programming fluently in Python or a comparable language.
Independent scientist with outstanding communication skills, a strong passion and commitment to science, who works well within a team.
Excited about building new methods to screen compounds at scale and to discover what drives cellular function and activity.
Preferred Qualifications:
Experience developing or deploying multiplexed imaging assays.
Experience with AI/ML applied to imaging or other high-dimensional biological data.
Experience with laboratory automation, liquid handling, and high-throughput experimental workflows.
Experience analyzing large-scale perturbation datasets and integrating multimodal data..
Elevate your research career to new heights with Genentech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey to becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research aligned with Genentech’s strategic ambitions.
The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. Throughout the program you will receive the mentorship and support necessary to develop into an independent scientist and leader.
The Genentech Postdoc Program (http://careers.gene.com/us/en/students-postdocs) provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to the Genentech Postdoctoral Program and unlock your full potential!
The expected salary range for this position based on the primary location of South San Francisco, California is $100,000 to $106,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits (https://roche.ehr.com/default.ashx?CLASSNAME=splash)
Relocation benefits are available for this job posting.
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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare – a strategy that aims to fit the right treatment to each patient in the best way possible. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. Thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Roche has been recognised as the Group Leader in sustainability within the Pharmaceuticals, Biotechnology & Life Sciences Industry ten years in a row by the Dow Jones Sustainability Indices (DJSI). For more information, please visit https://careers.roche.com Read our community guidelines here: https://www.roche.com/some-guidelines.htm #Roche #Biotechnology #Pharmaceuticals #Diagnostics #Healthcare #PersonalisedHealthcare #GreatPlaceToWork #Innovation
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Based on 364 listings with disclosed salaries, most healthcare jobs in South San Francisco, CA pay between $106k–$274k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 412 open healthcare positions in South San Francisco, CA listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Roche, Allergan, Cytokinetics, MSD, Amgen, among others. Browse the listings above to see every active employer.
Yes — 104 of the 412 open healthcare positions offer remote or hybrid work (9 remote, 95 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
