Gaithersburg, Maryland, United States · On-site
$114k–$182k/yr
Gaithersburg, US | full time | Job ID: 11410 About the Role: As a Senior Scientist I in Process Development at BioNTech, you will play a key role in advancing our antibody pipeline, which is central to our therapeutic st…
Skills: Downstream Processing, Process Development, Monoclonal Antibodies, Scale-up, Technology Transfer
Gaithersburg, Maryland, United States · Hybrid
$136k–$204k/yr
Leverage technology to impact patients and ultimately save lives Do you have expertise in, and passion for information technology? Would you like to apply your expertise to impact the IT strategy in a company that follow…
Skills: Detection Engineering, Threat Modeling, MITRE ATT&CK, SIEM, EDR
Gaithersburg, Maryland, United States · On-site
$120k–$127k/yr
(ID: 2026-2888) Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organiz…
Skills: Aseptic Technique, Mammalian Cell Culture, Monoclonal Antibodies, Plasmid Design, Molecular Cloning
Gaithersburg, Maryland, United States · On-site
$120k–$127k/yr
(ID: 2026-2887) Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organiz…
Skills: Recombinant Protein Purification, GMP Clinical-Phase Products, Downstream Process Development, Technology Transfer, Viral Clearance Strategies
Gaithersburg, Maryland, United States · Hybrid
$166k–$217k/yr
WHY JOIN US? Evinova is a health-tech business focused on accelerating better health outcomes by advancing digital transformation across the life sciences sector. By combining science-based expertise, evidence-led rigor,…
Skills: Data Architecture, Data Modeling, Python, SQL, NoSQL
Gaithersburg, Maryland, United States · On-site
$130k–$140k/yr
ENABLE your future through light. Excelitas is a global technology leader with more than 7,500 employees, focused on delivering market-driven solutions to fulfill the illumination, optical, detection and imaging needs of…
Skills: Plasma Physics, Microwave Engineering, Team Leadership, UV Bulb Technology, Electromagnetic Simulation
Gaithersburg, Maryland, United States · On-site
$149k–$248k/yr
Job Family: Scientist Travel Required: None Clearance Required: Ability to Obtain Public Trust We are seeking a Scientist to support NIH with the development and clinical advancement of vaccine and therapeutic candidates…
Skills: Downstream Process Development, Protein Purification, Technology Transfer, Viral Clearance Strategies, Process Optimization
Gaithersburg, Maryland, United States · On-site
$74k–$124k/yr
Job Family: Scientist Travel Required: None Clearance Required: Ability to Obtain Public Trust What You Will Do: We are currently searching for Scientist to independently provide support services to satisfy the overall o…
Skills: Stable Cell Line Generation, Molecular Biology, RT-PCR, Next-Generation Sequencing, Gene Synthesis
Gaithersburg, Maryland, United States · Hybrid
$145k–$190k/yr
WHY JOIN US? Evinova is a health-tech business focused on accelerating better health outcomes by advancing digital transformation across the life sciences sector. By combining science-based expertise, evidence-led rigor,…
Skills: Agentic AI, LLM Orchestration, Multi-agent Systems, Python, TensorFlow
Gaithersburg, Maryland, United States · On-site
Compensation TypeHourly Highgate Hotels Highgate is a leading real estate investment and hospitality management company with over $15 billion of assets under management and a global portfolio of more than 400 hotels span…
Skills: Preventative Maintenance, Plumbing Repair, HVAC Maintenance, Electrical Repair, Carpentry
Gaithersburg, Maryland, United States · On-site
$125k–$187k/yr
OPENTEXT - THE INFORMATION COMPANY OpenText is a global leader in information management, where innovation, creativity, and collaboration are the key components of our corporate culture. As a member of our team, you will…
Skills: Unix/Linux, Shell Scripting, Perl, Expect, FTP
Gaithersburg, Maryland, United States · Hybrid
$166k–$217k/yr
WHY JOIN US? Evinova is a health-tech business focused on accelerating better health outcomes by advancing digital transformation across the life sciences sector. By combining science-based expertise, evidence-led rigor,…
Skills: Test Strategy, LLM Evaluation, RAG Validation, Playwright, Selenium
Gaithersburg, Maryland, United States · On-site
$120k–$145k/yr
Job DetailsLevel: ExperiencedJob Location: National Institutes of Health (NIH) - Gaithersburg Campus - Gaithersburg, MD 20878Position Type: Full TimeEducation Level: Ph.D.Salary Range: $120,000.00 - $145,000.00 Salary/ye…
Skills: AKTA Unicorn, MS Office, Microfluidics, Chromatography, Protein Purification
Gaithersburg, Maryland, United States · Hybrid
$124k–$165k/yr
WHY JOIN US? Evinova is a health-tech business focused on accelerating better health outcomes by advancing digital transformation across the life sciences sector. By combining science-based expertise, evidence-led rigor,…
Skills: Product Management, Technical Product Management, Business Analysis, AI Technologies, Stakeholder Management
Gaithersburg, Maryland, United States · On-site
$115k–$173k/yr
The Associate Director, External Operations, Cell Therapy – External Supply Management, leads external manufacturing partner operations. These operations span a network of CDMOs and external partners supporting cell ther…
Skills: CDMO Management, External Supply Management, Tech Transfer, Cell Therapy, GMP Operations
Gaithersburg, Maryland, United States · On-site
$108k–$195k/yr
Leidos is seeking Senior Cloud Systems Owners to join the Air Traffic Business Area within the Homeland Sector, supporting the development of next-generation flight service and air traffic systems. This work aligns with …
Skills: AWS, Kubernetes, Terraform, Cloud Architecture, Linux Administration
Gaithersburg, Maryland, United States · On-site
$70k–$126k/yr
Leidos is seeking Systems Integration and Test Engineers to join the Air Traffic Business Area within the Homeland Sector, supporting the development of next-generation flight service and air traffic systems. This work a…
Skills: System Integration, Software Testing, Agile Methodology, Test Plan Design, Debugging
Gaithersburg, Maryland, United States · Hybrid
$161k–$241k/yr
Introduction to role: Are you ready to lead nine-figure capital investments that accelerate life-changing medicines to patients? As an Associate Capital Project Director, you will turn bold business cases into operationa…
Skills: Capital Project Management, Strategic Leadership, Risk Mitigation, Budget Governance, Stakeholder Management
Gaithersburg, Maryland, United States · On-site
$87k–$157k/yr
Leidos is seeking a Sr. Software Development Engineer who will be a member of a dynamic team working on the Federal Aviation Administration’s En-Route Automation Modernization ERAM) system, which is the heart of the Next…
Skills: Real-Time Programming, Multi-Threaded Programming, Linux, SW/HW Integration, Automation
Gaithersburg, Maryland, United States · On-site
$67k–$85k/yr
Welcome! Under minimal supervision, performs diagnostic and service work on residential and/or light commercial HVAC equipment and accessories. Communicates with customer to answer questions, resolves problems, and ens…
Skills: HVAC Diagnostics, Heating and Cooling Repair, Ventilation Systems, Refrigeration Equipment, Electrical Troubleshooting
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
Lead the development, optimization, and characterization of downstream purification processes for monoclonal antibodies. Contribute to CMC documentation and regulatory submissions while managing scale-up and technology transfer activities.
Requires a PhD with 6+ years of experience or an MS with 8+ years of industry experience in biologics process development. Must have expertise in downstream unit operations and a strong understanding of PPQ/BLA readiness.
Gaithersburg, US | full time | Job ID: 11410
About the Role:
As a Senior Scientist I in Process Development at BioNTech, you will play a key role in advancing our antibody pipeline, which is central to our therapeutic strategy. This position offers the opportunity to actively contribute technical leadership to downstream processing development while supporting CMC strategy for regulatory submissions. You will be part of a dynamic, lab-based team that thrives on collaboration and innovation to drive impactful results.
In this role, you will leverage your expertise in downstream processing to develop scalable purification processes, optimize manufacturing workflows, and ensure compliance with global regulatory standards. Your ability to distill complex data into actionable insights will be critical in shaping BioNTech’s success in delivering novel therapies to patients worldwide.
Your Contribution:
Develop and qualify scale-down models for downstream purification processes to support monoclonal antibody manufacturing
Execute studies and FMEA assessments to establish critical process parameters and proven acceptable ranges for process characterization
Lead development, optimization, and characterization of downstream processes, including scale-up, virus/impurity clearance, and resin/membrane lifetime
Conduct downstream process unit operations such as depth filtration, chromatography, viral inactivation, viral filtration, tangential flow filtration, and formulation
Collaborate with cross-functional teams to design experiments, analyze results, support technology transfers, and meet project timelines
Contribute to CMC documentation by drafting process descriptions, characterization reports, QbD risk assessments, and other technical reports
Drive the creation of best practices and workflows for process development in a fast-paced environment
A Good Match:
PhD in Biomedical Engineering, Chemical Engineering, Biochemistry or related discipline with 6 plus years of relevant experience (including post-doctoral training), or MS with 8 plus years of industry experience
6 years’ experience in global pharma PD or MS&T for monoclonal antibodies or related biologics
Expertise in downstream process development including scale-up and technology transfer
Proven ability to design and execute process characterization studies using scale-down models that inform PPQ strategy
Strong understanding of biologics CMC processes including PPQ/BLA readiness; experience with antibody or ADC development preferred
Demonstrated technical leadership within cross-functional teams and programs
Willingness to travel domestically and internationally as required by program needs
Your benefits and remuneration:
Expected Pay Range: $113,600/year to $181,600/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.
BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:
…and more! More details to be shared.
Located in the BioHealth Capital Region near Washington DC and ranked among the top biopharma hubs in the country, Gaithersburg, Maryland offers a unique and diverse cluster across industry, government, and academia for top talent and scientific innovation. As a pivotal player within the life sciences community, Gaithersburg is distinguished by its robust infrastructure and strategic location near the nation’s capital. The city’s strategic significance is amplified by its state-of-the-art manufacturing facilities that cater to the rigorous demands of the life sciences industry; Gaithersburg’s manufacturing sector is defined by advanced technologies and complies with the most stringent regulatory standards, ensuring the production of high-quality pharmaceuticals, biologics, and medical devices. In the coming years, Gaithersburg will continue to be a vital contributor to the future of medical science and technology.
Apply now - We look forward to your application!
Apply for our Gaithersburg, US location and simply send us your documents using our online form.
By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.
Our vision is to harness the power of the immune system to develop novel therapies against cancer & infectious diseases.
Biopharmaceutical New Technologies (BioNTech) is a global biotechnology company aspiring to translate science into survival by developing new immunotherapies utilizing the full potential of the immune system to fight cancer and infectious diseases. BioNTech is headquartered in Mainz, Germany, and operates globally with almost 7.000 pioneers. Our work is powered by one mission: Improving the health of people worldwide. We believe that scientific rigor and passion are the driving forces that are essential for innovative progress. BioNTech was founded in 2008 by scientists and physicians to translate science into survival by combining fundamental research and operational excellence. At BioNTech, we have been conducting fundamental research of mRNA technologies in the field of individualized cancer medicine for more than a decade. Some of our colleagues, including our co-founders, have been researching and developing mRNA-based vaccines for more than 25 years. Ready to join us on this journey? Explore the opportunities and become part of a team that aspires to turn bold ideas into real-world solutions: https://www.biontech.com/int/en/home/careers.html 🔗 Privacy Statement: https://www.biontech.com/int/en/home/data-privacy-statement.html 🔗 Imprint: https://www.biontech.com/int/en/home/imprint.html
Offices: An der Goldgrube 12, Mainz, Rhineland-Palatinate 55131, DE · Vollmersbachstraße 66, Idar-Oberstein, Rhineland-Palatinate 55743, DE · Vollmerstr. 5, Berlin, Berlin 12489, DE · Am Klopferspitz 19a, Planegg, Bavaria 82152, DE · Forstenrieder Str. 8-14, Neuried, Bavaria 82061, DE
Based on 88 listings with disclosed salaries, most engineering jobs in Gaithersburg, MD pay between $68k–$195k per year. Individual offers vary with seniority, company size, and specialization.
There are currently 98 open engineering positions in Gaithersburg, MD listed on Clera. New openings are added daily as companies post roles.
Companies currently hiring include Leidos, AstraZeneca, MESO SCALE DIAGNOSTICS, LLC., AAA Club Alliance, Asbury Communities, Inc., among others. Browse the listings above to see every active employer.
Yes — 29 of the 98 open engineering positions offer remote or hybrid work (1 remote, 28 hybrid).
Each listing links directly to the employer's application page. Apply early — fresh listings get the most recruiter attention in the first two weeks.
