Healthcare startups in San Francisco

Pairtu

San Francisco

Pairtu is a healthcare coordination platform connecting Medicare patients with dedicated advocates to navigate care and secure better outcomes, led by Harvard-educated entrepreneurs; it operates in a $60B market with million-dollar run-rate

Planbase

San Francisco

Planbase is a flexible AI-powered platform that embeds intelligence into operations, tailoring to each workflow to boost speed and accuracy; it serves healthcare organizations touching 100M+ patients, including $500M+ revenue leaders, with

Trellis AI

San Francisco

Trellis provides an AI agent that automates healthcare administrative workflows—such as intake, prior authorizations, and appeals—positioning itself as a solutions-focused partner to increase provider revenue while reducing administrative b

Novoflow

San Francisco

Novoflow deploys AI employees for medical clinics, building computer agents to modernize healthcare and automate front- and back-office tasks across a fragmented 400+ EHR ecosystem; contracts secured, backed by YC advisers and top investors

Indigo (In Stealth)

San Francisco

An AI healthcare startup enabling physicians to own independent practices, aiming to reshape healthcare. It achieved product-market fit in under 9 months with ARR of xMM and a pipeline to xxMM by 2026, led by technologists, physicians, engi

Wedge

San Francisco

AI Employees for Healthcare

Blank Bio

San Francisco

RNA intelligence for precision medicine

Amby Health

San Francisco

The health coach that texts you first

Exin Therapeutics

San Francisco

AI drug discovery platform for neurotherapeutics

Uncommon Therapeutics

San Francisco

A Disease Focused Biotech, Building Multiple Billion Dollar Drugs

Aegis

San Francisco

AI Agents to win denied health insurance claims.

Frekil

San Francisco

RWE Generation in minutes

Durate

San Francisco

Self-running physician scheduling

Medplum

San Francisco

Medplum is an open-source, API-first electronic health record (EHR) platform that increases access to and usefulness of medical data, used by major digital health and life sciences companies to build medical applications.

Finni Health

San Francisco

Finni Health enables autism care providers to start, run, and grow their own practice with a dedicated platform, backed by General Catalyst, Greymatter, and Y Combinator, as the market expands with rising diagnoses and enabling legislation.

Datrics

San Francisco

Datrics, a San Francisco-based company with 22 employees, develops generative AI for healthcare coding automation, led by CEO Anton Vaisburd and founded by Kirill Kirykov and Volodymyr Sofinskyi, both seasoned data science and analytics exe

Multiply Labs

San Francisco

Multiply Labs, a 36-person San Francisco-based company founded in 2016 by Fred Parietti and Alice Melocchi, delivers pharmaceutical automation via a pharma robotics as a service model, enabling life-saving therapies and partnering with glob

MDalgorithms

San Francisco

MDalgorithms is a remote, AI-driven dermatology and hair care company building custom deep learning models, native apps, and e-commerce APIs. It runs MDacne, a dermatology app with millions of downloads, and MDhair, a regrowth kit, backed b

Daybreak Health

San Francisco

Daybreak Health is a YC-backed provider of comprehensive online mental health care for youth and families aged 5–19. It partners with public school districts and insurers to cover costs and aims for zero-cost care and profitability by 2026.

Collectly

San Francisco

Collectly is a profitable healthcare tech startup that uses proprietary EHR interfaces to simplify billing, accelerate cash flow, and enhance the patient financial experience, serving 300k+ patients daily across U.S. practices with AI-drive

Clipboard

San Francisco

Clipboard connects workplaces with nearby professionals to turn extra time and ambition into career growth and financial opportunity. It is a Y Combinator W17 company founded by Wei Deng, a Yale and Yale Law School graduate.

Verge Genomics

San Francisco

Verge Genomics uses AI and human tissue data in its CONVERGE platform to map disease biology, identify targets, and de-risk drug development, with two drugs in clinical trials, 282 targets discovered, and partnerships worth $1.6B.

Sample

San Francisco

Sample Healthcare is a profitable San Francisco-based healthcare AI company backed by notable investors including Kulveer Taggar, Zack Kanter, Homebrew Ventures, Y Combinator, and alumni from Retool, Stripe, Ambience Healthcare, and Watersh

Readily

San Francisco

Readily provides AI-powered compliance tools for healthcare organizations, aiming to build the compliance layer for every company and cut admin costs. Founded by Edward Tiong and Wei An Wang, it serves large healthcare clients and reports 3

SafeBeat

San Francisco

SafeBeat Rx is a healthcare tech company developing ECG software and a take-home kit to enable at-home initiation of heart medications, backed by YC Summer 2021 and pursuing clinician-approved AI-driven dosing and faster FDA pathways to red

Toothy AI

San Francisco

Toothy AI automates back-office operations for dental clinics using large language models, led by founders with proven AI-enabled B2B track records (Chen’s SoftBank-backed $1M ARR AI email solution; Kerrigan’s pre-ChatGPT LLM campaign tool)

Bunkerhill Health

San Francisco

Bunkerhill Health translates AI algorithms from leading research institutions (Stanford, Harvard, Johns Hopkins) into clinical use, bridging academic innovation and patient care. It markets a scalable AI healthcare solution and invites cust

Rinse

San Francisco

Rinse is an early, well-funded startup building the One Medical for dental to redesign the dental industry from the ground up, backed by investors such as Y Combinator, Optum Ventures, PJC, Global Founders Capital, and Liquid 2, among other

Candid Health

San Francisco

Candid Health uses data science and machine learning to automate medical billing and reduce costs in the US healthcare system. A Y Combinator W20 alum with strong investor backing and rising demand from potential customers.

Apero Health

San Francisco

Apero is a San Francisco-based Y Combinator-backed startup simplifying medical billing with greater transparency; it has raised about $240 million from notable investors and serves 30+ practices, some with 50+ providers, while actively hiri

RTHM

San Francisco

Self-learning care for complex illness

Arintra

San Francisco

Enterprise-grade AI for revenue assurance

Sophys

San Francisco

AI Agents for Healthcare Intake

Alixia

San Francisco

Targeting the Tumor Ecosystem to address cancer drug resistance.

Rosebud Biosciences

San Francisco

Growing micro-organs to find new drugs

Adni

San Francisco

The career community for healthcare workers

REPROSENT

San Francisco

Activating an overlooked force in medicine - the patient.