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Jobs at Lycia Therapeutics (Now Hiring) — 2 open

Lycia Therapeutics logoLycia Therapeutics

Senior Manager/Director Clinical Operations

South San Francisco, California, United States · Remote OK

$180k–$250k/yr

Senior+$302M raised

Lycia Therapeutics is a biotechnology company using its proprietary lysosomal targeting chimera (LYTAC) platform to discover and develop best-in-class therapeutics that degrade extracellular and membrane-bound proteins. …

Skills: Clinical Operations Management, CRO Management, Strategic Planning, Budgeting And Forecasting, ICH GCP Guidelines

Lycia Therapeutics logoLycia Therapeutics

Senior Director, Controller

South San Francisco, California, United States · Hybrid

$265k–$290k/yr

Senior+$302M raised

Lycia Therapeutics is a biotechnology company using its proprietary lysosomal targeting chimera (LYTAC) platform to discover and develop best-in-class therapeutics that degrade extracellular and membrane-bound proteins. …

Skills: U.S. GAAP, Financial Reporting, Technical Accounting, Audit Management, Tax Compliance

Lycia Therapeutics logo

Senior Manager/Director Clinical Operations

Lycia Therapeutics

South San Francisco, California, United States • Remote OK

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  • $180k–$250k/yr
  • Full-time
  • bachelor degree, postgraduate degree
  • Annual Bonus, Equity, Generous Benefits Package
  • Posted 11d ago
  • ~40 hrs/week

Responsibilities

Oversee and manage early phase clinical programs in collaboration with Contract Research Organizations (CROs). Responsible for strategic planning, financial tracking, and ensuring compliance with FDA and ICH GCP guidelines.

Requirements

Requires a bachelor's degree, with an advanced scientific degree strongly preferred. Candidates need 7-12+ years of progressive clinical operations experience in the pharmaceutical or biotech industry.

Full job description

Lycia Therapeutics is a biotechnology company using its proprietary lysosomal targeting chimera (LYTAC) platform to discover and develop best-in-class therapeutics that degrade extracellular and membrane-bound proteins. These proteins drive a wide range of difficult-to-treat diseases, including autoimmune and inflammatory conditions. Lycia was established in 2019 in collaboration with academic founder and Nobel Laureate Carolyn Bertozzi, Ph.D., professor of chemistry and HHMI investigator at Stanford University. In June, 2026, Lycia Therapeutics completed a $75 million Series D financing to advance its pipeline of LYTAC extracellular protein degraders into the clinic. Lycia is headquartered in South San Francisco. 

 

Visit https://lyciatx.com/ for more information.

Position Summary

The Senior Manager/Director Clinical Operations will be responsible for oversight and management of up to 2 early phase clinical programs in collaboration with the selected Clinical Research Organization (CRO).   

\nPrimary Responsibilities:
  • Create and execute clinical operational strategic plans in line with product strategy and resource allocation.
  • Develop study feasibility, cost estimates, input into contracts, work/change orders and analyze tools and processes to support outsourcing efforts.
  • Track clinical program study finances and monthly accruals and review/approve associated clinical site and vendor invoices.
  • Build, develop and train internal staff and external vendors, structure department for enhancing efficiency, and create a highly engaged work environment for attracting and retaining highly qualified clinical operations professionals.
  • Develop and ensure compliance with SOPs and guidelines, FDA regulations and current ICH GCP guidelines.
  • Oversee and maintain the relationships with Contract Research Organizations, vendors,  and  investigative sites.
  • Participate on clinical operations and study team meetings.
  • Maintain a high level of professional expertise through familiarity of clinical literature, knowledge of therapeutic area, current medical practice and pharmaceutical regulations.

Additional Expectations

  • Although a remote position, it may be necessary to travel to corporate headquarters up to 2 times per year.
  • Ability to travel to clinical sites or to the CRO, as necessary to support trial management.
Qualifications:
  • B.A/B.S required; M.S., PhD, PharmD, MD or other related advanced scientific degree strongly preferred.
  • Minimum of 7 years for manager and 12 years for director level with progressive advancement within clinical operations in the pharmaceutical/biotech industry.
  • Flexible and dynamic interpersonal approach, entrepreneurial by nature, a collaborative team player who works well with physicians, scientists, managers, peers, and staff.
  • Ability to manage in a consensus environment through teamwork, trust and shared expectations, influencing strategic direction of complex global clinical operations issues, solicit information, listen well, persuade others, make important decisions and shape outcomes.
\n
$180,000 - $250,000 a year
The expected base salary range for the Senior Manager is $180,000-$198,000 and for the Director is $225,000-$250,000. We encourage candidates of all levels to apply as there is often flexibility on job title and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications and internal equity. Lycia offers a competitive employment package that includes an annual bonus, equity, and a generous benefits package.
\n

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

 

Lycia and other biotech companies have recently noticed an increase in email and social media scams targeting job candidates in our industry. Please note Lycia will post any legitimate job openings directly on our website or through our recruitment partner, Lever. If you wish to verify the legitimacy of a job opening, you may contact us.

Related keywords

Clinical OperationsBiotechnologyLYTACCROFDAICH GCPSOPEarly Phase Clinical ProgramsPharmaceuticalsClinical Trial ManagementExtracellular Protein Degraders

About Lycia Therapeutics

LinkedInVisit site

Building the leading extracellular protein degradation company

Industry
Biotechnology Research
Company size
11-50 employees
Founded
2020
Headquarters
South San Francisco, California
LinkedIn followers
6,767
Total funding
$302M

At Lycia, we aim to eliminate the source of disease using the power of extracellular protein degradation. Our novel LYTAC therapeutics are designed to bind and remove disease-causing extracellular proteins by directing them into the cell for degradation via the lysosome. Focused initially on autoimmune and inflammatory diseases, our platform addresses gaps in targeting proteins outside the cell, offering new hope to patients who urgently need better options.

Offices: E Jamie Ct, South San Francisco, California 94080, US

Health CareBiotechnologyLife Science
View all jobs at Lycia Therapeutics

About Lycia Therapeutics

LinkedInVisit site

Building the leading extracellular protein degradation company

Industry
Biotechnology Research
Company size
11-50 employees
Founded
2020
Headquarters
South San Francisco, California
LinkedIn followers
6,767
Total funding
$302M

At Lycia, we aim to eliminate the source of disease using the power of extracellular protein degradation. Our novel LYTAC therapeutics are designed to bind and remove disease-causing extracellular proteins by directing them into the cell for degradation via the lysosome. Focused initially on autoimmune and inflammatory diseases, our platform addresses gaps in targeting proteins outside the cell, offering new hope to patients who urgently need better options.

Offices: E Jamie Ct, South San Francisco, California 94080, US

Health CareBiotechnologyLife Science
View all jobs at Lycia Therapeutics

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