San Francisco, California, United States · On-site
$180k–$250k/yr
About LatchBio We build the benchmarks that test whether frontier AI can actually do computational biology. Pharma, biotech, and solution providers rely on benchmarks.bio to evaluate and improve their AI systems - and we…
Skills: Agent Infrastructure, Model Benchmarking, Full Stack Web Development, Distributed Systems, Python
San Francisco, California, United States · On-site
$180k–$250k/yr
About LatchBio We build the benchmarks that test whether frontier AI can actually do computational biology. Pharma, biotech, and solution providers rely on benchmarks.bio to evaluate and improve their AI systems - and we…
Skills: Container Orchestration, Kubernetes, Postgres, AWS, Linux Fundamentals
San Francisco, California, United States · Remote OK
$120k–$180k/yr
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analy…
Skills: Oligonucleotide Drug Discovery, ASO/siRNA Design, RNA Therapeutics, Drug Target Validation, Mechanism-of-Action Studies
San Francisco, California, United States · Remote OK
$120k–$180k/yr
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analy…
Skills: Biochemistry, Biophysics, Bioengineering, Synthetic Biology, Virology
San Francisco, California, United States · On-site
$180k/yr
Member of Technical Staff, Biosecurity As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high perfo…
Skills: Synthetic Biology, Virology, Microbiology, Bioengineering, Cloning
San Francisco, California, United States · Remote OK
$120k–$180k/yr
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analy…
Skills: Biologics Discovery, Antibody Engineering, Protein Engineering, Python, R
San Francisco, California, United States · On-site
$140k–$180k/yr
Technical Recruiter As molecular data generation and frontier model intelligence grows, new approaches to biological intelligence are needed across the biotech industry. Latch works with 5,000+ scientists, 150+ R&D labs,…
Skills: Full-Cycle Recruiting, Technical Sourcing, Candidate Closing, ATS Management, Hiring Manager Alignment
Remote OK
$120k–$180k/yr
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analy…
Skills: Proteomics, Genomics, Python, R, Data Analysis
San Francisco, California, United States · On-site
$180k/yr
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analy…
Skills: Proteomics, Python, R, Genomics, Genetics Data Analysis
San Francisco, California, United States · On-site
$160k–$200k/yr
Seeking a ruthlessly efficient, 0-1, adaptable Special Projects Manager to join LatchBio! LatchBio The convergence of laboratory automation, high-throughput assays, and machine learning is moving the medium of biological…
Skills: Operational Architecture, Financial Modeling, Risk Assessment, Contract Redlining, Strategic Planning
San Francisco, California, United States · On-site
As molecular data generation and frontier model intelligence grows, new approaches to biological intelligence are needed across the biotech industry. Latch works with 5,000 scientists, 150+ R&D labs, and many frontier la…
Skills: Outreach, Relationship Building, Sales, Customer Success, AI Research
Remote OK
$120k–$180k/yr
As molecular data generation and frontier model intelligence grow, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high-performance agents for biological data analys…
Skills: Biosecurity, Biosafety, Pathogen Genomics, Infectious Disease Research, Synthetic Biology
San Francisco, California, United States · On-site
$120k–$180k/yr
As molecular data generation and frontier model intelligence grow, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high-performance agents for biological data analys…
Skills: Computational Surveillance, Metagenomic Analysis, Taxonomic Classification, Assembly, Variant Calling
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
Build the infrastructure powering the benchmarking pipeline, including data ingestion, eval design, and grading systems. Develop agent infrastructure and full-stack web features to support computational biology AI benchmarks.
Candidates should have a strong interest in computer systems such as compilers, databases, and distributed systems. Proven ability to design and ship products and apply systems engineering approaches to tooling and data systems is required.
About LatchBio
We build the benchmarks that test whether frontier AI can actually do computational biology. Pharma, biotech, and solution providers rely on benchmarks.bio to evaluate and improve their AI systems - and we're just getting started.
We released the first rigorous benchmark suites for biology agents. They contain hundreds of real-world problems drawn directly from industry workflows. Our research shows that harness design - the tools, prompts, and control flow around a model - moves outcomes as much as swapping the base model itself. This insight is reshaping how frontier labs think about building with AI.
We've grown revenue 6x in the past 12 months. We have a repeatable sales process and deep partnerships with 10X Genomics, Vizgen, Takara Bio, and AtlasXOmics. More importantly: we have more demand than we can meet. That's why we're scaling rapidly across engineering.
We're building benchmarks across omics, therapeutics, and surveillance. We need engineers to build the infrastructure that powers our benchmarking pipeline - data ingestion, eval design, grading systems, and infrastructure. Work with scientists and frontier models. Ship fast.
Here is a sample of engineering products we work on
Agent harness integrated with bio first tooling such as an in-house h5ad and genomics viewer
Distributed file-system with metadata on Postgres and blobs on S3
Cluster orchestrator designed to accept compute nodes from anywhere on the internet
Reactive Python-based notebooks for data analysis and visualization
Benchmarking harness with automated QC processes to validate and probe model failure
cases
You will be working on problems in software including but not limited to agent infrastructure and systems, model benchmarking at scale, full stack web development, developer and user experience, and process optimization. You will work on a small team and have control over the direction you take and problems you tackle. You may work on scaling and improving a large scale internal benchmarking platform, planning and delivering features to improve quality and speed, and supporting ever evolving customer requirements and difficult computational tasks. Where appropriate, your work may dip into research for agentic biology.
Interest in computer systems and their inner workings e.g. compilers, operating systems,
databases, distributed systems, programming language theory
Designed and shipped products that people love
Ability to apply process or systems engineering approach to tooling and data systems
We care about output and let people optimize their work in a way that works for them. Our engineering team is in-person in San Francisco. We run a daily standup where engineers talk through technical challenges and stay aligned on what matters most. You will own a product area and execute, working closely with seasoned Latch engineers, product managers, and designers. Mentorship happens through code review and working through hard problems together.
Our charter and continued mission is to accelerate biological science so that humanity can benefit from better bioengineering, whether that be medical technology, farming, or environmental conservation. If you are motivated to work on these problems surrounded by like-minded people, LatchBio may be a great fit for you.
Our process is typically completed within two weeks.
$180k–$250k/yr
Equity
Unlimited PTO (truly)
Waterfront office in China Basin, San Francisco
Free lunch and dinner
100% premium covered on Blue Shield's platinum health plan ($0 premium, $0 deductible)
401(k) plan options
Work visa sponsorship
Company-sponsored professional development
Agent.bio — The AI agent for biology
Benchmarks.bio — The benchmarks for biology agents
Console.latch.bio — The harness for agentic data analysis
Agent Infrastructure for Biology
Agent infrastructure for biology. Bundled with kits + machines to serve 300+ pharma, biotech and academic teams around the world.
Offices: San Francisco, CA 94103, US
Agent Infrastructure for Biology
Agent infrastructure for biology. Bundled with kits + machines to serve 300+ pharma, biotech and academic teams around the world.
Offices: San Francisco, CA 94103, US
