Boston, Massachusetts, United States · On-site
$55/hr–$60/hr
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software–…
Skills: AAV Cell Line Development, Lentiviral Vector Development, Transfection, Cloning, Cell Banking
Boston, Massachusetts, United States · On-site
$30/hr–$35/hr
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software–…
Skills: Mammalian Cell Culture, CHO Cell Line Engineering, Transfection, Cloning, Cell Banking
Boston, Massachusetts, United States • On-site
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The role involves developing stable producer cell lines for AAV and lentiviral vector therapeutics using transfection, cloning, and characterization. The candidate will also perform biological assays and support the creation of novel workflows to improve viral vector quality attributes.
Requires a B.S. or M.S. in Biological Engineering, Virology, or a related field with over 5 years of industry experience in viral vector producer cell line development. Proficiency in ddPCR, ELISA, flow cytometry, and genome engineering is highly desired.
Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.
We're seeking a Senior Associate Scientist to join our Synthetic Biology team on a 6 month contract. The ideal candidate will have a proven track record performing AAV and/or lentiviral vector stable producer cell line development in an industry setting. They will be a key contributor to our team, participating in the creation of stable producer cell lines for AAV and/or lentiviral vector therapeutics and research projects to improve our cell line development workflows. They will also work closely with Asimov’s synthetic biology and process development teams. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.
Perform AAV and/or lentiviral vector stable producer cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment
Perform biological assays including ddPCR, ELISA, and flow cytometry
Support innovation through development of novel workflows and applications
Support research projects to develop viral vector therapeutics with enhanced quality attributes such as empty/full ratio, potency and/or cell targeting
Work effectively as part of a cross-functional team in support of a synthetic biology design platform
Design experiments, analyze data, troubleshoot, and maintain detailed records
Represent the cell line development function on project teams, making decisions for cell line activities and effectively communicating results, progress and plans
This is a full-time, 6-month contract position providing maternity leave coverage. While the role is intended to support this temporary need, there may be an opportunity to extend the contract or transition to a permanent position based on business needs.
B.S or M.S. in Biological Engineering, Virology, Cell Biology, Molecular Biology, or a related field
5+ years of hands-on experience in AAV and/or lentiviral vector producer cell line development in support of GMP production of cell or gene therapies
Experience performing transfections, viral transductions, flow cytometry, and quantitative gene expression analyses (ddPCR, qPCR, ELISA) is highly desired
Experience with viral genome engineering, and/or host cell genome engineering related to virus production or producer cell line technologies is highly desired
Strong written and verbal communication skills required
We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.
Intelligent design of living systems
Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.
Offices: 201 Brookline Ave, Suite 1201, Boston, Massachusetts 02215, US
Intelligent design of living systems
Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.
Offices: 201 Brookline Ave, Suite 1201, Boston, Massachusetts 02215, US
