Seattle, Washington, United States · Hybrid
$135k–$169k/yr
A-Alpha Bio is an early-stage and rapidly growing drug discovery company headquartered in Seattle, WA. We are enabling the next generation of high-impact therapeutics by combining high-throughput synthetic biology to mea…
Skills: Cybersecurity, Cloud infrastructure, AWS, Microsoft 365, Entra ID
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The Manager of Information Security & Technology will own and lead the company's information security, cloud infrastructure, and technology governance programs. This includes direct execution of cybersecurity initiatives, vendor management, and the development of a multi-year technology roadmap.
Candidates must have a bachelor's degree and at least 7 years of experience in IT, cybersecurity, or cloud administration. Proficiency in AWS, Microsoft 365, and NIST-aligned security frameworks is required.
A-Alpha Bio is an early-stage and rapidly growing drug discovery company headquartered in Seattle, WA. We are enabling the next generation of high-impact therapeutics by combining high-throughput synthetic biology to measure protein-protein interactions at scale with state-of-the-art machine learning to predict how proteins bind. We partner with leading pharmaceutical and biotechnology companies to enable the discovery of antibodies, molecular glues, and other protein interaction-related drugs. In parallel, we use our wet-lab and computational platforms to discover and develop an internal pipeline of biologics and molecular glues to improve human health.
This role is not open to remote applicants and would require relocation to Seattle, WA.
Starting Salary Range: $135,000 - $169,000 annually
Exemption Status: Exempt
Location Expectations: Hybrid
Reporting To: VP, Finance & Operations
A-Alpha Bio is seeking a Manager, Information Security & Technology to own and lead our information security and technology program – encompassing information security, cloud infrastructure, laboratory technology, and technology governance. Success in this role depends on a combination of strategic planning and technical implementation, the ability to build strong internal and external partnerships, and a sense of ownership and accountability for technology outcomes. This position will require direct ownership, execution, and vendor management, rather than delegation through a dedicated internal team.
Required
Preferred
About A-Alpha Bio
A-Alpha Bio is a biotechnology company that leverages synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions. Our AlphaSeq platform applies synthetic biology to experimentally measure millions of protein interaction affinities simultaneously. Protein binding data is incorporated into our AlphaBind platform to train machine learning models that predict binding from sequence. We use both platforms to discover and optimize high-impact therapeutics for our pipeline and in partnership with leading pharmaceutical and biotechnology companies.
In 2018, A-Alpha Bio spun out of the University of Washington’s Institute for Protein Design and Center for Synthetic Biology – both communities filled with brilliant and highly entrepreneurial scientists. Since the company’s inception, we have focused on an oncology-centered internal pipeline along with pharma and biotech partnerships to collaboratively train predictive machine learning models and discover and optimize drugs for therapeutic areas ranging from infectious disease to neurodegeneration. New members of the team should expect a fast-paced, highly dynamic, and interdisciplinary work environment. We are building a diverse, meritocratic, and supportive team that shares our values of speaking the truth, shooting for the moon, taking the reins, playing for the team, and improving the world.
A-Alpha Bio is headquartered in a custom designed lab and office space in downtown Seattle’s Belltown neighborhood. While the startup lifestyle occasionally requires grueling hours, we strongly value the need for a work-life balance. We are fortunate to be situated in a region that is renowned for its premier outdoor activities, including hiking, biking, climbing, skiing, kayaking, sailing, and more. At A-Alpha, you’ll find many who love the outdoors, but also gamers, amateur chefs, explorers, sports fans, bakers, crafters, photographers, brewers, jetsetters, animal lovers, and artists. Whatever your passions, you belong at A-Alpha Bio!
The protein-protein interaction company
A-Alpha Bio is a biotechnology platform company that measures, predicts, and engineers protein-protein interactions at scale. Its experimental platform, AlphaSeq, enables the rapid and quantitative measurement of millions of protein-protein binding affinities simultaneously. Its AI platform, AlphaBind, is trained on the world’s largest protein-protein interaction database and predicts binding strength from sequence. A-Alpha Bio works with pharmaceutical and biotechnology companies through both strategic partnerships and streamlined services, leveraging AlphaSeq and AlphaBind to engineer next-generation dual-specific and molecular glue therapeutics, discover and optimize differentiated biologics, and generate protein binding and structural data at scale to power AI models. A-Alpha Bio is based in Seattle and is a spinout from the University of Washington’s Institute for Protein Design.
Offices: 2101 4th Ave, Fifth Floor, Seattle, Washington 98121, US
The protein-protein interaction company
A-Alpha Bio is a biotechnology platform company that measures, predicts, and engineers protein-protein interactions at scale. Its experimental platform, AlphaSeq, enables the rapid and quantitative measurement of millions of protein-protein binding affinities simultaneously. Its AI platform, AlphaBind, is trained on the world’s largest protein-protein interaction database and predicts binding strength from sequence. A-Alpha Bio works with pharmaceutical and biotechnology companies through both strategic partnerships and streamlined services, leveraging AlphaSeq and AlphaBind to engineer next-generation dual-specific and molecular glue therapeutics, discover and optimize differentiated biologics, and generate protein binding and structural data at scale to power AI models. A-Alpha Bio is based in Seattle and is a spinout from the University of Washington’s Institute for Protein Design.
Offices: 2101 4th Ave, Fifth Floor, Seattle, Washington 98121, US
