All startups in San Francisco

Tessel AI: Rigorous Medical Imaging AI Evaluation for Hospitals

San Francisco

Tessel builds evidence infrastructure for safety-critical AI, providing independent validation and benchmarking for medical imaging AI in collaboration with academic centers, delivering standardized metrics and regulatory-aligned evidence t

April

San Francisco

April is an AI Executive Assistant for email and calendar that is voice-first and productivity-obsessed, backed by Y Combinator; it launched in August and has shown traction as it grows, aiming to give every busy professional the assistant

Planbase

San Francisco

Planbase is a flexible AI-powered platform that embeds intelligence into operations, tailoring to each workflow to boost speed and accuracy; it serves healthcare organizations touching 100M+ patients, including $500M+ revenue leaders, with

Nell

San Francisco

Nell reimagines media for the AI era, aiming to transform how people engage with content. Led by SoundCloud's founder, Nell seeks to be world's leading generative-media company with highest quality and to democratize access to personalized

Exponent

San Francisco

Exponent builds specialized software engineering agents to automate the software engineering lifecycle for large engineering teams. By envisioning engineers managing fleets of AI agents, it aims to shape the future of software engineering a

Meridian

San Francisco

The company catalyzes the next generation of consumer experiences by redefining how people interact with products and services, driving innovation in everyday engagement and shaping how brands are experienced in modern markets.

Augrade

San Francisco

Augrade Inc is an AI research lab building an agentic platform to automate construction workflows across design, estimation, and vendor management, aiming to create an AI architect and engineer that can realize projects for users regardless

Ohm

San Francisco

Ohm is a San Francisco-based AI-first company applying AI to battery research, validation, and manufacturing workflows. Backed by Y Combinator and other investors, it leverages a lean, multidisciplinary team of engineers, creatives, and PhD

Swizzl

San Francisco

Swizzl helps car dealers convert hesitant leads into confident buyers before they walk through the door, generating more ready-to-buy traffic and smoother closes for auto dealerships with a no-pressure, no-chasing approach to lead conversat

Tally

San Francisco

A stealth accounting AI startup focused on AI for accounting, backed by high-profile investors and leaders from Shopify, Rippling, OpenAI, Bill.com, and Airtable, signaling strong confidence in its approach within the AI and accounting spac

Kalos

San Francisco

Kalos is an early-stage, high-growth startup in San Francisco, currently in stealth mode, that has built Blue, an AI agent.

Domu Technology Inc. (YC S24)

San Francisco

Domu Technology Inc. automates debt-collection calls for banks and insurers, serving six Fortune 500s and major firms including MetLife, BBVA, and BNP Paribas Cardif. A YC alum with a female-led team, it reduces costs and improves recovery

Cua

San Francisco

Cua builds infrastructure for general AI agents to safely use computers and apps. It offers an open-source framework and cloud sandboxed container platform, a seed round, 9k+ GitHub stars in four months, and a research-backed blueprint for

Trellis AI

San Francisco

Trellis provides an AI agent that automates healthcare administrative workflows—such as intake, prior authorizations, and appeals—positioning itself as a solutions-focused partner to increase provider revenue while reducing administrative b

Chief AI

San Francisco

It builds a system of AI-native products to supercharge leaders in government and the C-suite, shaping a leadership-focused approach across government and the executive suite.

Chima

San Francisco

Chima helps leading institutions customize and scale generative AI by integrating and analyzing private and public data to privately leverage commercial LLMs; it builds infrastructure for enterprises to customize LLMs and automate functions

Cardinal

San Francisco

The company offers an AI platform branded as The AI Platform for Precision Outbound, providing AI-powered tools for precision outbound outreach.

Dalus

San Francisco

Dalus develops AI-powered software that makes hardware design feel like software development, targeting aerospace, robotics, and defense. Founded in 2024 by Eliot and Sebastian, it has revenue and completed YC W25.

Tread ai

San Francisco

Tread is an AI-powered operating system for construction materials logistics, serving producers, contractors, and haulers in a $91B market. It unifies the ecosystem on a system of record, eliminating spreadsheets, text threads, and lost tic

Sci-Phi

San Francisco

Sci-Phi (SciPhi-AI) is an AI tooling company building an open-source, multi-purpose LLM framework for retrieval-augmented generation (RAG) and synthetic data creation, used by developers to build and evaluate AI agents.

Palm

San Francisco

Palm specializes in business identity management, pursuing the future of Business Identity. It uses AI and data identity to manage and securely share business identity information with partners, enabling controlled access and permissioning.

Outspeed

San Francisco

Outspeed provides tools and infrastructure for building real-time multimodal AI applications, enabling developers to create real-time AI experiences across multiple modalities. Backed by Pear VC and Audacious Ventures.

A37

San Francisco

The company offers a generative AI-driven platform to automate and optimize DevOps workflows, reducing cloud overspend and deployment delays. It targets startups and enterprise DevOps teams and has raised an X.XM funding round from a tier-1

Promptless

San Francisco

Promptless builds AI teammates that integrate with users’ existing workflows, serving startups and Fortune 500 enterprises. It ranked among the top W25 by revenue; small founding team has led startups, published LLM research, and graduated

Sepal AI

San Francisco

Sepal AI provides PhD-level experts for AI model development, backed by YC-backed founders from Vercel and Turing. Since 2024, it has raised millions and counts Fortune 500s and top AI labs as customers, building the largest global talent g

Prelude AI

San Francisco

The company is building an AI-native platform that makes financial advisors more effective, transforming wealth management by advancing advisory capabilities with advanced technology. Backed by a world-class founding team from top fintech a

Verne Robotics

San Francisco

.

Conductor Quantum

San Francisco

Conductor Quantum, based in San Francisco, develops software to enable fault-tolerant quantum computation. A small team of quantum physicists, hardware engineers, and machine learning experts envisions scalable operation of thousands to bil

Humeo

San Francisco

The company operates an AI-powered short video content creation platform and aims to build the fastest content-creation engine on earth, offering participants significant ownership from day one.

Entangl

San Francisco

Entangl uses AI to autonomously detect design errors in data center engineering and operations, delivering targeted solutions to engineers. Founded by Shapol and Antanas, ex-reusable rocket program leaders, Entangl aims to save time, reduce

Novoflow

San Francisco

Novoflow deploys AI employees for medical clinics, building computer agents to modernize healthcare and automate front- and back-office tasks across a fragmented 400+ EHR ecosystem; contracts secured, backed by YC advisers and top investors

Onlook

San Francisco

Onlook provides the fastest way to build, deploy, and iterate websites and web apps, bridging design and development. It reached #1 on Hacker News and was the top-trending GitHub repository with 19,000+ stars, founded by Daniel Farrell and

Additive AI

San Francisco

Additive AI, founded in San Francisco, builds AI-powered tools to automate document-heavy tax and accounting workflows; acquired by Thomson Reuters in 2025, it operates as part of a global leader to help professionals make faster, more info

Pearson Labs

San Francisco

Pearson Labs presents itself as a small, high-impact, lean team focused on delivering meaningful results, emphasizing impact over scale; no information is available about its mission, products, services, or market position.

Fractional AI

San Francisco

Fractional AI builds bespoke generative AI software to move AI from concept to production, with all projects deployed. Based in San Francisco, it employs senior engineers and emphasizes experienced, high impact delivery, and is actively hir

Indigo (In Stealth)

San Francisco

An AI healthcare startup enabling physicians to own independent practices, aiming to reshape healthcare. It achieved product-market fit in under 9 months with ARR of xMM and a pipeline to xxMM by 2026, led by technologists, physicians, engi

Archon

San Francisco

Archon develops automated, full-stack systems to secure critical public infrastructure and advance national cybersecurity at the intersection of national security and infrastructure protection. The company is rapidly growing, signaling mome

Chestnut

San Francisco

Chestnut is the first AI mortgage lender licensed in Texas and Colorado, completed YC X25 and backed by Y Combinator and Olive Tree Capital, founded by Spencer Brown to disrupt the $128B mortgage market with AI.

Conduit Intelligence

San Francisco

The company develops noninvasive thought-to-text technology to bridge communication between people and devices by reducing the language barrier.

Ego

San Francisco

Ego is a startup building an Infinite Game—a persistent virtual 3D world with embodied AI agents. Led by Vishnu Hari (ex-Facebook AI, Meta Reality Labs), it leverages Unreal Engine, C++, AWS, Azure, and Roblox, and participates in YC Launch