The Opportunity
Our Translational Genetics Team focuses on providing
molecular analysis of genetic variants, to deliver early, accurate diagnosis and
inform best treatment for children living with genetic and rare diseases. The
team applies functional genomics to interpret patient genetic variants, utilising
induced pluripotent stem cells and directed differentiation to create personalised,
and patient-specific disease models.
We now have an exciting opportunity for a Senior
Research Officer to join our team to assist with our goal of reducing the time
for patient diagnosis from 5+ years to less than three months. This research will
involve the ongoing development of high throughput screening approaches for genetic
variant assessment. The screening platforms aim to interpret novel genetic
variants to support patient diagnosis, inform disease, and screen for
personalised best treatment options.
The position involves project development and
experimental design utilising the latest in induced pluripotent stem cell
disease modelling, CRISPR/Cas9 gene editing, and next generation sequencing
approaches.
The role will encompass techniques such as single-cell
RNAseq, ATAC-seq, targeted amplicon sequencing, methylation sequencing, and
long read sequencing. The applicant will have a comprehensive knowledge of
these approaches to support supervision and training of staff and students,
assist with data analysis, and interpret research findings.
In this role you will have the opportunity to develop
a world-leading rare disease research portfolio to deliver diagnosis and
treatment to rare disease children in Western Australia and across the globe.
Key responsibilities:
- Develop new high-throughput CRISPR and single cell assays for genetic variant analysis.
- Design experiments to best interpret patient phenotype using appropriate disease models.
- Single cell RNA sequencing, bulk RNA sequencing, ATAC-seq, long read sequencing.
- Grant writing, preparation of manuscripts for publications, conference presentations, and clinical reporting.
- Contribution to research and clinical meetings for patient variant interpretation.
- Student and staff supervision.
Based in our modern offices within Perth’s Children’s Hospital, this
position will be offered on a full-time basis for an initial 2-year period.
About You
The successful candidate will hold a PhD in Molecular Biology,
Cell Biology, Genetics or a related discipline, preferably with 10+ years
research experience or strong track record in the field. You will also
demonstrate:
- Extensive experience in molecular biology and cell biology methodology.
- Demonstrated experience in next generation sequencing.
- Application of long-read single cell transcriptomics, isoform-resolved transcriptomic analysis, spatial transcriptomics, and integrative multi-omics approaches.
- Expertise in iPSC disease modelling cardiac and neural.
- Capacity to identify research priorities and deliver project outcomes.
- Track record in scientific paper preparation and securing competitive research funding.
- Demonstrated capacity to lead multidisciplinary research projects.
- Ability to work collaboratively as part of a team, and lead others.
- High-level written and oral communication skills.
At
The Kids Research Institute Australia, we are committed to building a workplace
culture that reflects the communities we serve. We actively recruit
support and welcome applications from Aboriginal and Torres Strait Islander
people, people with disability, culturally and linguistically diverse
communities, LGBTQIA+ people, people of all ages, and those with diverse lived
experiences. We also provide reasonable adjustments throughout the recruitment
process and in the workplace, ensuring everyone has the opportunity to
thrive.
If you meet many, but not all, of the role
requirements, we encourage you to apply. We also welcome you to mention any
career breaks in your cover letter to help us understand your journey.
Our commitment to diversity and inclusion is
reflected in how we:
- Support staff-led inclusion and allyship groups.
- Offer flexible work practices that recognise different needs and life stages.
- Provide training, development and mentoring opportunities to increase inclusive leadership and create an environment where all staff can thrive.
- Partner with communities to strengthen cultural awareness and belonging.
- Ensure adjustments and accessible practices are available for diverse community groups.
- We continually strive to measure our progress and improve where we can.
Alongside our inclusive culture, you’ll
enjoy:
- Extra annual leave at Christmas and Easter.
- Salary packaging and entertainment benefits.
- Health and wellbeing programs with weekly events.
- Flexible working options.
- Recognition and professional development opportunities, including LinkedIn Learning.
- Modern offices with sit-to-stand desks and end-of-trip facilities.
- Staff discounts on travel, IT, stationery, and access to corporate health insurance.
How to Apply
If this
role feels like the right fit and an exciting new opportunity for you, please
click on 'Apply Now' to visit our Career Site, view the Job Description,
and submit your application.
Please
include a cover letter (no more than 2 pages) that specifically addresses the
skills and experience outlined in the “About You” section.
Applications
will only be accepted through our career portal. If you are experiencing
technical difficulties or require reasonable accommodations in completing your
application, please contact [email protected].
Click here for the Job Description
Contact Name: Vanessa Fear
Contact Email: [email protected]
Closing Date: 25/08/2026 - We reserve the right to hire prior to the closing date.