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Full-time
postgraduate degree
Posted 18h ago
~40 hrs/week
Responsibilities
The role involves analyzing large-scale multi-omics datasets to derive biological insights for drug discovery and biomarker development. The candidate will develop scalable computational pipelines and collaborate cross-functionally to interpret results and elucidate mechanisms of action.
Requirements
Requires a Ph.D. in Computational Biology, Bioinformatics, or Systems Biology with strong proficiency in Python, R, or Perl. Candidates must have proven experience with high-throughput sequencing data and familiarity with bioinformatics tools and workflow management systems.
Full job description
JOB DESCRIPTION
Job Title: Computational Biologist
Job Location: Bangalore
Department: Computational And Data Sciences
About Syngene: Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit
Mandatory expectation for all roles as per Syngene safety guidelines
Overall adherence to safe practices and procedures of oneself and the teams aligned
Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
Compliance to Syngene’ s quality standards at all times
Hold self and their teams accountable for the achievement of safety goals
Govern and Review safety metrics from time to time
Core Purpose of the Role: We are seeking a highly motivated and experienced Computational Biologist to join our growing research and development team. The ideal candidate will apply advanced computational and statistical methods to analyze high-throughput biological data and generate actionable insights that support drug discovery, biomarker development, and disease biology research.
Role Accountabilities:
Analyze and interpret large-scale multi-omics datasets (genomics, transcriptomics, proteomics, single-cell, and spatial data) generated through high-throughput sequencing (NGS) and other platforms to derive actionable biological insights, including target identification and biomarker discovery.
Perform advanced bioinformatics analyses such as differential expression, pathway and enrichment analysis, variant calling, integrative multi-omics analysis, and network modeling.
Develop, optimize, and maintain scalable, reproducible computational pipelines for data processing, quality control, integration, and visualization across diverse datasets.
Lead and contribute to studies focused on target identification, mechanism-of-action (MoA) elucidation, and biomarker discovery using systems biology and data-driven approaches.
Utilize advanced statistical methods to identify patterns in biological data.
Mentor junior team members
Collaborate cross-functionally with experimental biologists, data scientists, and clinicians to interpret results.
Develop and maintain reproducible code and documentation for internal and external use.
Stay abreast of emerging technologies, databases, and tools in computational biology and bioinformatics.
Present results clearly in cross-disciplinary meetings.
Leadership Capabilities
Syngene Values
All employees will consistently demonstrate alignment with our core values
Excellence
Integrity
Professionalism
Specific requirements for this role
Demonstrated Capability
Strong proficiency in programming languages such as Python, R, or Perl for bioinformatics applications.
Proven experience with processing and analysis of high-throughput datasets (e.g., RNA-seq, WGS, ATAC-seq, single-cell, proteomics).
Familiarity with commonly used bioinformatics tools, databases (e.g., Ensembl, GEO, TCGA, UniProt), and workflow management systems (e.g., Nextflow, Snakemake).
Experience with version control (e.g., Git), reproducibility standards, and working in Linux/Unix environments.
Excellent problem-solving, analytical, and communication skills.
Education: Ph.D. in Computational Biology, Bioinformatics, Systems Biology,
Skills and Capabilities
Experience with machine learning, network biology, or statistical modeling in a biological context.
Exposure to drug discovery workflows, including target identification, validation, and translational research.
Familiarity with cloud computing platforms (e.g., AWS, Google Cloud, Azure) and containerization (e.g., Docker, Singularity).
Track record of publications in high-impact journals and/or contributions to open-source bioinformatics tools.
Experience with regulatory standards and clinical data integration is a plus.
Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.
Syngene International Ltd. (BSE: 539268, NSE: SYNGENE, ISIN: INE398R01022) is an integrated research, development, and manufacturing services company serving the global pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical sectors.
Syngene's more than 6000 scientists offer both skills and the capacity to deliver great science, robust data security, and quality manufacturing, at speed, to improve time-to-market and lower the cost of innovation.
With a combination of dedicated research facilities for Amgen, Baxter, and Bristol-Myers Squibb as well as 2 Mn sq. ft of specialist discovery, development and manufacturing facilities, Syngene works with biotech companies pursuing leading-edge science as well as multinationals, including GSK, Zoetis and Merck KGaA.
For more details, visit www.syngeneintl.com or write to us at [email protected]
Offices: Syngene International Ltd, Biocon Park, Bommsandra Industrial Estate, IV Phase, Jigani Link Road, Bommsandra, Bengaluru, Karnataka 560099, IN · Knowledge Square Park -9000, Plot NO.7, Survey No.542, MN Park, Synergy Square 2 Genome Valley, Kolthur Shamirpet, Medchal, Hyderabad, Hyderabad, Telangana 500078, IN · MSEZ, Permude, Mangaluru, Karnataka 574142, Mangaluru, Karnataka 574142, IN
Drug DiscoveryDrug DevelopmentDrug ManufacturingSmall MoleculesBiologicsIntegrated Drug DiscoveryPeptidesOligonucleotidesAntibody Drug ConjugatesPROTACs
Syngene International Ltd. (BSE: 539268, NSE: SYNGENE, ISIN: INE398R01022) is an integrated research, development, and manufacturing services company serving the global pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical sectors.
Syngene's more than 6000 scientists offer both skills and the capacity to deliver great science, robust data security, and quality manufacturing, at speed, to improve time-to-market and lower the cost of innovation.
With a combination of dedicated research facilities for Amgen, Baxter, and Bristol-Myers Squibb as well as 2 Mn sq. ft of specialist discovery, development and manufacturing facilities, Syngene works with biotech companies pursuing leading-edge science as well as multinationals, including GSK, Zoetis and Merck KGaA.
For more details, visit www.syngeneintl.com or write to us at [email protected]
Offices: Syngene International Ltd, Biocon Park, Bommsandra Industrial Estate, IV Phase, Jigani Link Road, Bommsandra, Bengaluru, Karnataka 560099, IN · Knowledge Square Park -9000, Plot NO.7, Survey No.542, MN Park, Synergy Square 2 Genome Valley, Kolthur Shamirpet, Medchal, Hyderabad, Hyderabad, Telangana 500078, IN · MSEZ, Permude, Mangaluru, Karnataka 574142, Mangaluru, Karnataka 574142, IN
Drug DiscoveryDrug DevelopmentDrug ManufacturingSmall MoleculesBiologicsIntegrated Drug DiscoveryPeptidesOligonucleotidesAntibody Drug ConjugatesPROTACs