South San Francisco, California, United States · On-site
$200k–$240k/yr
Deep Apple Therapeutics is a Bay Area biotechnology company with a focus on combining capabilities in molecular docking and structural biology to create a nucleus for accelerated drug discovery through advanced computer …
Skills: Molecular Pharmacology, GPCR Signal Transduction, Compound Screening, Assay Development, Small Molecule Drug Discovery
South San Francisco, California, United States · On-site
$102k–$130k/yr
Deep Apple Therapeutics is a Bay Area biotechnology company with a focus on combining capabilities in molecular docking and structural biology to create a nucleus for accelerated drug discovery through advanced computer …
Skills: Mammalian Cell Culture, Plate-based Assays, Fluorescence Microscopy, Immunocytochemistry, Recombinant Cell Line Generation
South San Francisco, California, United States · On-site
$120k–$163k/yr
Deep Apple Therapeutics is a Bay Area biotechnology company with a focus on combining capabilities in molecular docking and structural biology to create a nucleus for accelerated drug discovery through advanced computer …
Skills: Compound Screening, Molecular Biology, Cellular Techniques, GPCR Pharmacology, Signal Transduction
South San Francisco, California, United States · On-site
$200k–$240k/yr
Deep Apple Therapeutics is a Bay Area biotechnology company with a focus on combining capabilities in molecular docking and structural biology to create a nucleus for accelerated drug discovery through advanced computer …
Skills: Molecular Pharmacology, GPCR Signal Transduction, Compound Screening, Assay Development, Team Leadership
South San Francisco, California, United States • On-site
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Lead and mentor a team of scientists to drive small molecule research discovery from early screening to candidate nomination. Design and implement pharmacology assays to characterize mechanisms of action and signal transduction pathways.
Requires a PhD in Pharmacology, Biochemistry, Molecular Biology, or a related field. Candidates should have 8+ years of industry experience in small molecule drug discovery with deep expertise in receptor pharmacology.
Deep Apple Therapeutics is a Bay Area biotechnology company with a focus on combining capabilities in molecular docking and structural biology to create a nucleus for accelerated drug discovery through advanced computer aided drug design technologies. Deep Apple Therapeutics is applying a state-of-the-art technology research platform based on advanced computational modeling and large-scale compound docking (LSD), cryo-EM based structural biology, and deep learning to drug discovery.
We are seeking highly motivated and energetic scientists to join a dynamic and well-funded research organization. We have multiple openings in molecular biology, structural biology, deep learning and in vitro biology. Deep Apple Therapeutics offers a highly competitive compensation, equity, and benefits package.
We are seeking an experienced entrepreneurial leader to serve as Director of Molecular Pharmacology, driving small molecule research discovery at Deep Apple Therapeutics. Reporting to the Head of Biology, you will lead a team of scientists and technicians, building and executing the pharmacology strategy that advances compounds from early screening through candidate nomination. You will serve as the molecular pharmacology subject matter expert across our portfolio, contributing in vitro and in vivo expertise directly to project teams.
At Deep Apple, we value diversity, encourage professional growth, and provide competitive benefits and compensation.
Deep Apple is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
Accelerating drug discovery with structure-based large library virtual screening and deep learning models
In a vast, unexplored virtual chemical space, Deep Apple Therapeutics moves with unprecedented speed to discover novel small molecules for high-value targets. Deep Apple combines ensemble cryo-EM to explore receptor conformations; deep learning; and the docking of multi-billion compound libraries generated using the company's proprietary Orchard.ai™ algorithm. Deep Apple's deep learning discovery engine is built upon founder expertise in computational modeling, protein and target structure determination, large-scale molecular docking, and the elucidation of protein dynamics and conformational transitions. This structure-based, machine-learning driven drug design approach enables the company to rapidly advance novel candidates addressing well-validated targets in inflammatory, metabolic, and endocrine diseases. For more information, visit deepappletx.com.
Offices: San Francisco Bay Area, US
Accelerating drug discovery with structure-based large library virtual screening and deep learning models
In a vast, unexplored virtual chemical space, Deep Apple Therapeutics moves with unprecedented speed to discover novel small molecules for high-value targets. Deep Apple combines ensemble cryo-EM to explore receptor conformations; deep learning; and the docking of multi-billion compound libraries generated using the company's proprietary Orchard.ai™ algorithm. Deep Apple's deep learning discovery engine is built upon founder expertise in computational modeling, protein and target structure determination, large-scale molecular docking, and the elucidation of protein dynamics and conformational transitions. This structure-based, machine-learning driven drug design approach enables the company to rapidly advance novel candidates addressing well-validated targets in inflammatory, metabolic, and endocrine diseases. For more information, visit deepappletx.com.
Offices: San Francisco Bay Area, US
