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Jobs at CytomX Therapeutics (Now Hiring) — 2 open

CytomX Therapeutics logoCytomX Therapeutics

Associate Scientist, Protein Sciences

South San Francisco, California, United States · On-site

$115k–$135k/yr

Senior$695M raised

Associate Scientist, Protein Sciences Headquarters Location: South San Francisco, CA, Company relocating to Emeryville, CA Fall of 2026 Candidate Location: Onsite for lab work Travel Required: 5-10% Reports To: Senior Sc…

Skills: Protein Purification, AKTA Systems, LC-MS, HPLC, UPLC

CytomX Therapeutics logoCytomX Therapeutics

Associate Scientist, Oncology Research

South San Francisco, California, United States · Hybrid

$115k–$135k/yr

Senior$695M raised

Associate Scientist, Oncology Research Headquarters Location: South San Francisco, CA, Company relocating to Emeryville, CA Fall of 2026 Candidate Location: Onsite for lab work Travel Required: Reports To: Senior Scienti…

Skills: Cell-Based Assays, Tissue Culture, Flow Cytometry, Cytokine Analysis, Elisa

CytomX Therapeutics logo

Associate Scientist, Protein Sciences

CytomX Therapeutics

South San Francisco, California, United States • On-site

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  • $115k–$135k/yr
  • Full-time
  • postgraduate degree
  • Competitive Total Rewards Program, Career Growth And Learning Curriculum, Work Life Balance Support
  • Posted 20d ago
  • ~40 hrs/week

Responsibilities

Develop protein production and purification strategies for PROBODY programs, including antibodies, bispecifics, and cytokines. Create analytical and biophysical methods, specifically using LC-MS, to characterize novel molecules and support the transition from discovery to clinical development.

Requirements

Requires a PhD in Biochemistry/Protein Chemistry or an MS with 5+ years of industry experience. Must have expertise in AKTA systems, HPLC/UPLC, and various protein characterization assays.

Full job description

Associate Scientist, Protein Sciences

Headquarters Location: South San Francisco, CA, Company relocating to Emeryville, CA Fall of 2026
Candidate Location: Onsite for lab work
Travel Required: 5-10%
Reports To: Senior Scientist II
Department: Protein Sciences & Early CMC
Position Type: Full-time, Exempt
About CytomX Therapeutics:
CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel PROBODY® therapeutic platform. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives. Our workplace embodies collaboration, open communication, celebrating our successes, and holding each other to the highest possible standards. CytomX’s robust and differentiated pipeline comprises therapeutic candidates across multiple treatment modalities including antibody-drug conjugates (“ADCs”), T-cell engagers, and immune modulators such as cytokines. CytomX’s clinical-stage pipeline includes CX-2051 and CX-801. Learn more at www.cytomX.com.
Who You Are and What You’ll Do:
You are passionate about the life sciences and making a difference for cancer patients, their families, and healthcare providers. You will be responsible for developing protein production and purification strategies to support all discovery PROBODY programs at CytomX, as well as developing analytical methods—including LC-MS—to characterize these novel molecules. Additionally, you will work closely with the Protein Engineering and Research teams to transition therapeutic programs from discovery to clinical development.
Job Responsibilities:
• Develop parallel purification processes for antibodies, bispecifics and cytokines
• Collaborate with discovery, protein engineering and pharmacology to provide therapeutic and reagent proteins of appropriate quality for use in in vitro and in vivo studies.
• Develop production and purification strategies for various PROBODY bispecific formats
• Solving protein purification problems based on scientific principles, current technologies, and personal experience
• Support the lead selection process by developing various analytical, LC-MS and biophysical methods to characterize novel PROBODY molecules.
• Participating in cross-functional discovery supports and effectively communicates information to appropriate groups and protein sciences staff.
Minimum Qualifications:
• PhD in Biochemistry or Protein Chemistry or related discipline OR MS in Biochemistry with 5+ years of experience in the biotechnology or biopharma industry with increasing responsibility
• Expertise in problem solving the protein purification issues is required.
• Expertise in large and small-scale protein purification using AKTA systems, Tecan or Janus liquid handler system is required.
• Expertise in protein characterization assays such as concentration, endotoxin measurement, SDS-PAGE, CE-SDS, SEC-HPLC, RP-HPLC, HIC and IEF are required.
• Hands-on experience in operating HPLC or UPLC instruments is required.
• Experience in developing analytical methods to characterize antibodies, bispecifics and cytokines is required.
• Experience in managing the protein purification workflow is required
• Please note that a presentation of a scientific seminar is required during the interview process
Preferred Qualifications:
• Experience in antibody therapeutics is preferred.
• Expertise in molecular biology techniques such as cloning, sequencing, etc. is desired.
• Hands-on experience in operating various mass spec instruments and associated software for data analysis preferred.
• Expertise in developability assessment of therapeutic biologics molecules is required
How You Will Work:
• Demonstrates collaboration and teamwork. Works well with others and understands that collaboration leads to better results.
• Possesses strong communication skills. Communicates clearly, concisely, and professionally. Listens actively to build understanding.
• Exhibits strong interpersonal skills and self-awareness. Builds and cultivates strong and enduring relationships with others. Acts with humility and understands own strengths and weaknesses.
• Shows continuous improvement and a commitment to self-management and development. Operates with a continuous improvement mindset and continuously seeks to expand own knowledge and capabilities.
• Demonstrates a patient focus. Puts the patient first in actions and decisions taken.
Compensation, Benefits, and So Much More
• The expected salary range for this role based on the primary location for this position in California is $115,000 - $135,000 per year. Offer amounts are determined by factors such as experience, qualifications, geographic location, and other job-related factors permitted by law.
• A great environment where we work collaboratively, leverage each other’s strengths, and work toward a shared vision with our common goals of doing the best thing for patients.
• A robust and enduring approach to your development and career growth fueled by a strong learning curriculum and career guidance that helps you understand how you can grow your career at CytomX.
• A robust and highly competitive total rewards program that helps you achieve your compensation goals while supporting a great work / life balance.
Conditions of Employment
• Background investigations are required for all positions at CytomX, consistent with applicable law.
• This role is not eligible for visa sponsorship.
CytomX’s Commitment to Diversity, Equity, Inclusion, and Belonging (DEIB)
CytomX believes that DEIB helps drive our success, and we encourage candidates from all identities, backgrounds, and abilities to apply. We are an equal opportunity employer committed to building an inclusive, innovative work environment with employees who reflect our values and ultimately, serve our patients. Therefore, in all aspects of the employment process, we provide employment opportunities to all qualified applicants without regard to race, color, religion, sex, disability, age, sexual orientation, gender identity or expression, pregnancy, medical condition related to pregnancy, creed, ancestry, national origin, marital status, genetic information, or military status, or any other protected status in accordance with applicable law.
Further, we are committed to the full inclusion of all qualified individuals. As part of this commitment, we (and the agencies we work with) will assist individuals who have a disability with any reasonable accommodation requests related to employment, including completing the application process, interviewing, completing any pre-employment testing, participating in the employee selection process, and/or to perform essential job functions where the requested accommodation does not impose an undue hardship. If you have a disability and require reasonable accommodation, or need other assistance in applying for or interviewing for this position, please direct your inquiries to Human Resources, at [email protected]
Notice to Recruiters/Staffing AgenciesRecruiters and staffing agencies should not contact CytomX Therapeutics through this page. We require that all Recruitment Vendors (e.g., search firms, recruitment agencies and staffing companies) have a fully executed, formal written agreement on file with CytomX prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited. Unsolicited vendor submissions do not constitute any actual or implied contract with CytomX, and CytomX will not be responsible for any purported fees. For more information, please contact our HR team at [email protected]
Please review our Applicant Personal Information Processing Notice to understand what types of personal information we collect from job applicants and why we process such information.

Related keywords

Protein SciencesEarly CMCPROBODYAntibody-Drug ConjugatesADCsT-cell EngagersImmune ModulatorsAKTATecanJanus Liquid HandlerSDS-PAGECE-SDSSEC-HPLCRP-HPLCHICIEF

About CytomX Therapeutics

LinkedInVisit site

Transforming lives with safer, more effective therapies

Industry
Biotechnology
Company size
51-200 employees
Headquarters
South San Francisco, CA
LinkedIn followers
12,392
Total funding
$695M

CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel Probody® therapeutic platform. We have a broad pipeline comprised of five clinical-stage programs, with even more in development. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation, and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives. Our workplace embodies collaboration, open communication, celebrating our successes and holding each other to the highest possible standards. CytomX embraces diversity and seeks to enhance and maintain our culture of equity and inclusion which encourages individuals to be themselves, feel involved, respected and connected. We at CytomX believe that we benefit from each other’s ideas and experiences. We accept our differences and learn from one another, improve together, and embrace change to achieve our corporate and individual objectives. This belief applies to how we work together at CytomX, how we work with others outside CytomX, how we represent CytomX in our communities, and how we endeavor to bring our scientific innovations to a diverse patient population. CytomX acknowledges the importance of diversity, equity and inclusion initiatives and that they require an evolving and ongoing commitment. CytomX is an equal opportunity employer and does not discriminate against any individual or potential candidate because of race, color, religion, sex, national origin, sexual preference or any other legally protected category. CytomX is located in South San Francisco, California, the birthplace of biotechnology. Learn more about us and how we are advancing science to treat cancer differently at www.cytomX.com.

Offices: 151 Oyster Point Blvd, South San Francisco, CA 94080, US

Health CareBiotechnologyPharmaceuticalTherapeutics
View all jobs at CytomX Therapeutics

About CytomX Therapeutics

LinkedInVisit site

Transforming lives with safer, more effective therapies

Industry
Biotechnology
Company size
51-200 employees
Headquarters
South San Francisco, CA
LinkedIn followers
12,392
Total funding
$695M

CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel Probody® therapeutic platform. We have a broad pipeline comprised of five clinical-stage programs, with even more in development. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation, and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives. Our workplace embodies collaboration, open communication, celebrating our successes and holding each other to the highest possible standards. CytomX embraces diversity and seeks to enhance and maintain our culture of equity and inclusion which encourages individuals to be themselves, feel involved, respected and connected. We at CytomX believe that we benefit from each other’s ideas and experiences. We accept our differences and learn from one another, improve together, and embrace change to achieve our corporate and individual objectives. This belief applies to how we work together at CytomX, how we work with others outside CytomX, how we represent CytomX in our communities, and how we endeavor to bring our scientific innovations to a diverse patient population. CytomX acknowledges the importance of diversity, equity and inclusion initiatives and that they require an evolving and ongoing commitment. CytomX is an equal opportunity employer and does not discriminate against any individual or potential candidate because of race, color, religion, sex, national origin, sexual preference or any other legally protected category. CytomX is located in South San Francisco, California, the birthplace of biotechnology. Learn more about us and how we are advancing science to treat cancer differently at www.cytomX.com.

Offices: 151 Oyster Point Blvd, South San Francisco, CA 94080, US

Health CareBiotechnologyPharmaceuticalTherapeutics
View all jobs at CytomX Therapeutics

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