Watertown, Massachusetts, United States · On-site
$195k–$218k/yr
Description About Century Therapeutics: Century Therapeutics (NASDAQ: IPSC) is a biotechnology company advancing a pipeline of induced pluripotent stem cell (iPSC)-derived cell therapies with the potential to meaningfull…
Skills: Translational Strategy, Biomarker Development, Assay Validation, CRO Management, Immune Phenotyping
Watertown, Massachusetts, United States • On-site
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The Director will lead the translational science and biomarker strategy for early-phase clinical programs, specifically focusing on Type 1 Diabetes and CAR-T therapies. This includes overseeing assay development, managing CRO relationships, and leading a high-performing scientific team to ensure translational readiness.
Requires a PhD in Immunology or a related field with over 10 years of industry experience in clinical translational science and leadership. Candidates must have a proven track record of driving programs through IND and first-in-human milestones, preferably in cell and gene therapy.
Description
About Century Therapeutics:Century Therapeutics is seeking a Director of Translational Sciences to serve as a senior scientific and organizational leader driving translational strategy across our early-phase clinical programs, with a primary focus on Type 1 Diabetes (T1D) and CAR-T cell therapies. This is a high-impact leadership role with broad accountability for translational science, biomarker strategy, assay development, CRO oversight, and team growth. Reporting to the Head of Immunology & Translational Sciences, the Director will set and drive the strategic agenda for translational sciences, partner across Early Clinical Development, Computational Biology, Regulatory Affairs, and external CRO networks to ensure translational readiness and scientific rigor across first-in-human and early-phase trials. The Director will operate with significant independence, lead cross-functional decision-making, and serve as the internal and external face of Century’s translational science capabilities. The ideal candidate brings deep scientific expertise, a track record of leading biomarker and translational programs through IND and early-phase clinical milestones, and the leadership presence to build a high-performing team, influence senior stakeholders, and represent Century in industry forums and with regulatory agencies.
The expected salary range for this role is approximately $195,000 - $218,000 depending on experience. Additional benefits offered include but are not limited to an annual performance-based bonus (prorated by start date), medical, dental, and vision insurance, matching 401K plan, and 20+ days per-year of PTO (prorated by start date). Additionally, employees not requiring sponsorship are preferred.
Requirements
Clinical Translational Strategy & Execution
• Experience supporting or leading translational science for first-in-human cell or gene therapy trials.
• Familiarity with immune monitoring in autoimmune disease, including T1D or related indications.
• Contributions to INDs, clinical protocol development, regulatory amendments, or responses from a translational science perspective.
• Track record of external scientific contributions: publications, conference presentations, patents, or regulatory interactions.
Century Therapeutics Inc. is an Equal Employment Opportunity/Affirmative Action Employer - Minority/Female/Disability/Veteran. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or veteran status or any other characteristic protected by federal, state, or local law.
Advancing iPSC-derived cell therapies to transform care in autoimmune disease and cancer
Century Therapeutics is an innovative biotechnology company that is building an industry-leading, allogeneic, iPSC-derived cell therapy platform that integrates cutting-edge gene editing, protein engineering, technical development and manufacturing capabilities to generate allogeneic, iPSC-derived therapies for autoimmune diseases and cancer. Please note: Century Therapeutics does not solicit prospective Colleagues directly via Telegram (or other social media sites) or require potential candidates to make purchases of goods or services.
Offices: 25 N 38th St, 11th Floor, Philadelphia, Pennsylvania 19104, US · 260 Evans Way, Branchburg, New Jersey 08876, US · 201 Brookline Ave, Boston, Massachusetts 02215, US
Advancing iPSC-derived cell therapies to transform care in autoimmune disease and cancer
Century Therapeutics is an innovative biotechnology company that is building an industry-leading, allogeneic, iPSC-derived cell therapy platform that integrates cutting-edge gene editing, protein engineering, technical development and manufacturing capabilities to generate allogeneic, iPSC-derived therapies for autoimmune diseases and cancer. Please note: Century Therapeutics does not solicit prospective Colleagues directly via Telegram (or other social media sites) or require potential candidates to make purchases of goods or services.
Offices: 25 N 38th St, 11th Floor, Philadelphia, Pennsylvania 19104, US · 260 Evans Way, Branchburg, New Jersey 08876, US · 201 Brookline Ave, Boston, Massachusetts 02215, US
