Boston, Massachusetts, United States · On-site
$112k–$118k/yr
(Boston, MA) Principal Associate Scientist sought by Ascidian Therapeutics, Inc. to design, validate, execute, and interpret experiments to improve therapeutic performance of designer RNA editing molecules & contribu…
Skills: RNA Therapeutics, Pre-mRNA Splicing, Protein Translation, Cloning, RNA Exon-editing
Boston, Massachusetts, United States · On-site
Scientist I - RNA Therapeutic Discovery (6-month contract) Ascidian is redefining the treatment of disease by rewriting RNA. Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were …
Skills: Mammalian Cell Culture, iPSCs, AAV Vectors, Plasmid Design, Cloning
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Design, validate, and execute experiments to improve the performance of designer RNA editing molecules. Contribute to the characterization of drug candidates to support the Roche Collaboration.
Requires a Master's degree with 3 years of experience or a Bachelor's degree with 5 years of experience in a related biological field. Must have specific expertise in RNA therapeutics, pre-mRNA splicing, and various molecular biology laboratory techniques.
(Boston, MA) Principal Associate Scientist sought by Ascidian Therapeutics, Inc. to
design, validate, execute, and interpret experiments to improve therapeutic performance
of designer RNA editing molecules & contribute to characterization of drug candidates to
support Ascidian’s Roche Collaboration. Req.’s Master’s Deg. in Molecular/Cellular
Bio., Bio. Chem. or rel. field & 3 yrs rel. exp. or Bach’s Deg. & 5 yrs rel. exp. Must have
experience in RNA therapeutics with a focus on pre-mRNA splicing and protein
translation; designing and cloning RNA exon-editing molecules and designing assays to
measure RNA editing; optimization and preparation of custom Illumina libraries;
bioinformatic analysis of the libraries; cell culture, ddPCR, qPCR and protein extraction
and characterization by JESS and western blot, Sanger sequence analysis; use of
sequence design and analysis software.
Apply to: https://grnh.se/7figxnp64us
No calls.
Salary: $ 112,017 to $118,400 per year.
The final salary offer will be determined based on several factors, including the candidate’s relevant experience, specific skills, and internal equity.
Rewriting RNA
Ascidian Therapeutics is redefining the treatment of disease by rewriting RNA. By editing exons at the RNA level, Ascidian therapies enable precise post-transcriptional editing of genes, resulting in full-length, functional proteins at the right levels, in the right cells, at the right time. With active discovery and preclinical programs in ophthalmology, neurological and neuromuscular disorders, and other rare diseases, Ascidian is opening new therapeutic possibilities for patients in need of breakthroughs. For more information, visit www.ascidian-tx.com.
Offices: 80 Guest St, Boston, Massachusetts 02135, US
Rewriting RNA
Ascidian Therapeutics is redefining the treatment of disease by rewriting RNA. By editing exons at the RNA level, Ascidian therapies enable precise post-transcriptional editing of genes, resulting in full-length, functional proteins at the right levels, in the right cells, at the right time. With active discovery and preclinical programs in ophthalmology, neurological and neuromuscular disorders, and other rare diseases, Ascidian is opening new therapeutic possibilities for patients in need of breakthroughs. For more information, visit www.ascidian-tx.com.
Offices: 80 Guest St, Boston, Massachusetts 02135, US
