Sr Manager, Enterprise Business Systems

JOB SUMMARY

We are seeking an experienced and results-driven Sr Manager, Enterprise Business Systems to join our growing IT team. This role will oversee the implementation, configuration, maintenance, and support of business-critical applications across the organization, with primary focus on the systems that run our General & Administrative (G&A) functions: Finance and Accounting, People/HR, Legal and Compliance, and Facilities, IT Operations, and Business Operations.

The Sr. Manager, Enterprise Business Systems will collaborate with leaders across each G&A function to optimize workflows, troubleshoot system issues, and drive continuous improvement in business processes. This role ensures that business applications operate efficiently, securely, and meet the evolving strategic and tactical needs of the company.

This position will be based out of our San Diego Headquarters.

KEY RESPONSIBILITIES

• Apply deep working knowledge of enterprise software across the G&A landscape to implement, integrate, and maintain business applications supporting:

• Finance and Accounting (ERP, budget forecasting & tracking, procurement, invoicing & expenses),

• People/HR (HRIS, payroll, talent acquisition, learning management)

• Legal and Compliance (contract lifecycle management, e-signature, entity management)

• Facilities/Operations (service management, asset and space management).

• Ensure application security, role-based access controls, segregation of duties, and compliance with company policies across all G&A systems.

• Perform regular system updates, patches, and upgrades to maintain performance and security.

• Liaise with software vendors and service providers for application support and upgrades.

• Integrate business applications with other systems and third-party tools and assist in data migrations, imports, and exports between systems.

QUALIFICATIONS

• Bachelor’s degree in Information Technology, Computer Science, Business Administration, or a related field.

• 12 years IT experience, with 8+ years administering cross-functional business applications spanning multiple G&A functions, life sciences experience preferred

• Experience supporting financial processing and audit controls for Sarbanes-Oxley compliance, as well as the access, confidentiality, and retention requirements of HR and Legal systems.

• Working knowledge of data privacy and associated regulatory requirements such as GDPR, CCPA, HIPAA, and Transparency Reporting.

• Strong experience implementing, maintaining and improving Finance, Procurement, HR, Legal and Compliance systems such as NetSuite, Adaptive, Procurify, HRIS, Ashby ATS, DocuSign, and Ironclad preferred

• Experience managing SaaS vendor relationships, contracts, renewals, and license optimization across a portfolio of business applications.

• Experience in system implementation, data migration, or process automation.

• Excellent communication and collaboration abilities with strong analytical and problem-solving skills.

• Prior experience with IT service management, identity and access management (SSO, SCIM, provisioning), and corporate IT or facilities systems preferred

• Experience with reporting methodologies and business metrics preferred

• Project management experience or certifications (e.g., PMP, ITIL, Agile) preferred

ABOUT IAMBIC THERAPEUTICS
Iambic Therapeutics (Nasdaq: IAM) is a technology and clinical-stage life sciences company headquartered in San Diego. By utilizing molecular superintelligence — integrating proprietary AI with automated, scalable chemistry and biology experimentation — our platform is designed to address the totality of drug discovery and development. At Iambic, we are building an engine that is designed to power the future of medicine. Learn more at iambic.ai.

MISSION & VALUES
Our mission is to make better technology for better medicines. Three values guide how we work:

• Bold. We are courageous, take thoughtful risks, and approach challenges with tenacity.

• Innovative. We are creative and find new solutions that deliver impact.

• Collaborative. We respect one another and partner with integrity.

We value the range of perspectives our people bring, and we work to build an environment where every team member can contribute and grow.

PAY AND BENEFITS
The pay range for this role is listed above. Actual pay depends on factors including experience, skills, and location. Eligible employees in the U.S. receive company-paid medical coverage, flexible spending accounts, voluntary life insurance, 401(k) matching and flexible time off. We are in a brand-new state-of-the art facility in beautiful San Diego with a community gym, dining, and easy access to great places to live and play.

EQUAL OPPORTUNITY
Iambic is an equal opportunity employer. We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, ancestry, age, disability, medical condition, genetic information, marital status, veteran or military status, or any other characteristic protected by law.