Sr. Manager, Enterprise Risk Management & Business Continuity

Louisville · On-site$112k – $209k

About this role

The Position

This role is a highly valuable part of our Enterprise Risk Management (ERM) and Business Continuity Management (BCM) team, which is committed to safeguarding Genentech’s primary US distribution network and ensuring the uninterrupted delivery of life-saving medicines to patients. As a core member of this team, you will protect critical supply chains by designing robust strategies to mitigate enterprise-level operational risks and vulnerabilities. You will have the opportunity to collaborate closely with cross-functional leaders across Logistics, Trade Compliance, Global Security, and Executive Leadership to build a resilient, risk-aware culture. Together, we act as a stabilizing force to ensure our transformational treatments securely and reliably reach the patients who need them most.

The Opportunity

The Senior Manager, Enterprise Risk Management & Business Continuity is a high-impact individual contributor responsible for designing, implementing, and continuously improving the comprehensive ERM and BCM programs at Genentech’s Primary US Distribution Center in Louisville, KY. This critical role safeguards US commercial pharmaceutical distribution and secures the continuity of the majority of Roche's global pharma revenue against enterprise-level disruptions. Key responsibilities include:

  • Drive Program Maturity: Lead and scale end-to-end ERM and BCM frameworks aligned with ISO 31000 and ISO 22301 standards across all PT US Supply Chain functions, including Logistics, Sales & Operations Planning, and Trade Compliance.

  • Command Crisis Readiness: Establish and lead the site’s Crisis Management Team by designing activation structures, communication protocols, and high-fidelity annual readiness exercises (tabletops, drills, and simulations).

  • Mitigate Supply Chain Interruptions: Conduct comprehensive Business Impact Analyses (BIAs) and formulate documented recovery strategies to minimize operational downtime and protect critical pharmaceutical inventory.

  • Oversee Physical Security Integration: Manage site security operations—including contract providers, surveillance architectures, and regulatory compliance (FDA/DEA)—while seamlessly embedding physical security threats into the overarching ERM framework.

  • Direct Insurance & Claims Portfolio: Coordinate site asset exposure documentation and claims management alongside Roche Group Insurance and external brokers to leverage data-driven risk transfer strategies.

  • Establish Collaborative Governance: Design cross-functional risk steering committees and RACI models to embed risk ownership across diverse site operations without relying on direct authority.

  • Harmonize Global Standards: Serve as the primary facility liaison to Roche’s global risk and security networks, aligning local operations with global best practices while partnering with external 3PLs and regulatory bodies.

Who You Are

  • You possess a Bachelor’s degree in a relevant field (e.g., Supply Chain, Risk Management, Business Administration) and possess a Certified Business Continuity Professional (CBCP) designation, or the ability to obtain it within 18 months.

  • Matrix Navigator: Proven track record of collaborating successfully within a global, highly matrixed organization, driving alignment between local site priorities and global corporate network standards.

  • Expert Influencer: Exceptional ability to build senior-level coalitions, earn rapid credibility, and comfortably drive accountability among cross-functional stakeholders without direct hierarchical authority.

  • Experienced Resilience Leader: 10–15 years of progressive experience in ERM, BCM, crisis management, or physical security, including at least 5 years within a highly regulated sector like pharmaceuticals, biotech, or healthcare logistics.

  • Strategic Communicator: Outstanding facilitation and communication skills, with a demonstrated ability to translate complex risk metrics and scenario analyses into clear, actionable executive-level insights.

The expected salary range for this position based on the primary location of Kentucky is $112,400 - $208,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at this link.

Relocation is not approved for this position.
This is an on-site position; no remote options are offered at this time.

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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Company at a glance

About Genentech

We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal.

Making a difference in the lives of millions starts when you make a change in yours. If you’d like to join our team, view our openings at gene.com/careers.

Our patient resource center is dedicated to getting patients and caregivers to the right resources. You can reach them at 1 (877) GENENTECH (436-3683)
Monday-Friday, 6am-5pm PST or [email protected].

Community Guidelines

  1. We want to foster positive conversation around the issues we are passionate about. To that end, we remove profanity, content that contains threatening language, content that is aimed at private individuals, personal information, and repeated unwanted messages.
  1. Don’t mention any medicines by name — ours or anyone else’s.

Because of the fair balance rules governing our industry, we cannot post any comments that reference any pharmaceutical brand, product, or service. Please do not mention any specific medicines by name, or include any links to third party sites in your comments.

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This site is not intended as a forum for reporting side effects experienced while taking a Genentech product. Instead, you should report any side effects to Genentech Drug Safety at 1-888-835-2555. You can also report side effects of any prescription product directly to the FDA at 1-800-FDA-1088 or by visiting www.FDA.gov/medwatch.

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Founded1976
Team Size10,001+ employees
WorkspaceOn-site
IndustryBiotechnology Research
Location
Louisville, Kentucky, United States
Websitegene.com
LinkedInLinkedIn

Top Benefits

  • Annual Bonus

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