Consultant / Contractor SVP Clinical Development Fibrosis
About this role
Alentis Therapeutics, the Claudin-1 Company, is on a mission to treat cancer and reverse fibrosis. To this end, we are rapidly advancing a clinical pipeline of anti-Claudin-1 monoclonal antibodies. Our team is committed to unlocking the broad potential of our therapeutic target Claudin-1 and bringing much-needed medicines to patients suffering from solid tumors as well as kidney, liver, and lung fibrosis.
Tasks
The SVP of Clinical Development Fibrosis, reporting to the Chief Medical Officer, will oversee clinical research, medical management, and study execution for the Company’s clinical program for Lixudebart and is a key member of the Research and Development Leadership Team.
- Leading the strategic development of Lixudebart in cooperation with the CMO and executive LT
- Provide medical and scientific leadership across the strategy, execution, interpretation, and communication of clinical data related to Lixudebart.
- Driving execution of the Lixudebart clinical programs in partnership with the Head of Clinical Operation and other key line functions eg Regulatory.
- Supporting the PV ensuring overall safety of Lixudebart and supporting overall program safety reporting in collaboration with Safety colleagues.
- Leading the medical input into Clinical Development Plan (CDP), Integrated Development Plan (IDP) and Clinical Trial Protocol (CTP) reviews, and contributing to/driving development of disease clinical standards for new any disease areas.
- Work with Research/ Translational Medical Sciences to drive transition of pre-PoC (Proof of Concept) projects to DDP (Development Decision Point) and with BD&L (Business Development & Licensing) including target identification and due diligences together with other medical matters, as needed.
- As a medical expert, leading interactions with external and internal stakeholders and decision boards.
- Serve as a scientific and medical spokesperson for the company when appropriate.
Requirements
- MD or equivalent medical degree is required in addition to advanced knowledge and clinical training in medical/scientific area; Nephrology practice experience 4 years.
- Experience with early and late stage clinical development & research, including pivotal trials, in kidney diseases, especially rare kidney disease.
- Relationship and experience leading or being a critical team member for key regulatory activities, such as end-of-phase trial meetings, INDs, Marketing Authorization, special designations. Especially rare and kidney divisions.
- Leading clinical program team in a matrix organization.
- Having high impact and hands on experience supporting BD, IR and other external activities.
- Strong and existing relationship with KOLs that can be leveraged by Alentis.
As a consultant, the individual is expected to be onsite in Switzerland for 1-2 days every two weeks. The remainder of the work can be performed remotely, providing flexibility while maintaining regular in-person collaboration with the team and key stakeholders.
Company at a glance
Alentis Therapeutics is a clinical-stage biotechnology company pioneering first-in-class antibody-drug conjugates (ADCs) and antibodies targeting Claudin-1 (CLDN1) for oncology and multi-organ fibrosis. CLDN1 is a previously unexploited target that plays a key role in the pathology of cancer and fibrotic disease. Alentis is the leading company pioneering CLDN1 ADCs and antibodies to modify and reverse the course of select diseases.
Alentis was founded based on ground-breaking research in the laboratory of Prof. Thomas Baumert, MD at the University of Strasbourg and the French National Institute of Health and Medical Research (Inserm). Alentis is headquartered at the pharma-biotech hub in Basel, Switzerland. Visit www.alentis.ch
Tired of cold applications?
Sign up with Clera and we'll reach out the moment a role actually fits you — no more spraying applications into the void.
Know someone who'd be great for this?