Oxford BioTherapeutics

Biotechnology11-50 employeesWebsite

3

Open Roles

Oxford BioTherapeutics is a biotechnology company focused on the development of antibody therapeutics for the treatment of cancer. The company currently has between 11-50 employees. Oxford BioTherapeutics is currently hiring for three on-site positions: * **Senior Scientist Mass Spectrometry (Proteomics):** This role will lead the mass spectrometry proteomics laboratory at OBT’s Oxford research facility. The Senior Scientist will generate quantitative proteomics data from human tissues to support OBT’s OGAP verify, oncology target discovery platform. Responsibilities include maintaining and operating Thermo Exploris nano-LC mass spectrometers, training staff in mass spectrometry and proteomics, conducting routine data generation on human oncology samples, collaborating with bioinformatics, supporting human tissue analysis, and generating data for collaborations and new business development. * **Research Associate In Silico:** This on-site position in Oxford supports the discovery, investigation, and presentation of cancer therapeutic targets using bioinformatics-based approaches. The Research Associate will assist with bioinformatics pipelines, routine tasks supporting business development, target discovery, and US labs. Additional responsibilities include working with the bioinformatics team, creating and developing new and existing bioinformatic tools, and analyzing, summarizing, and presenting data. * **Scientist/Sr./Principal Scientist, ADC & Translational Research:** This on-site position focuses on the Oncology ADC pipeline, developing first-in-class ADC therapies. The Scientist will design and execute in vitro and ex vivo experiments, utilize molecular and cell-based techniques, collaborate with various teams, conduct binding affinity assays, and expand in-house capabilities for ADC toxicity. The role involves applying ML/AI approaches and conducting translational research experiments. The technology stack used at Oxford BioTherapeutics includes: Mass Spectrometry, Proteomics, Protein Biochemistry, Bioinformatics, Data Analysis, Method Development, Line Management, Thermo Mass Spectrometers, Nano-HPLC Systems, Quantitative Proteomics, Data Recording, Oncology Knowledge, Proteogenomic Methods, NGS Knowledge, Targeted Quantitation Methods, Cancer Biology, Pharmacology, Antibody-Drug Conjugates, Molecular Techniques, Cell-Based Techniques, Biological Evaluations, Statistical Design, Problem Solving, Collaboration, Communication, Translational Research, Biomarker Discovery, Machine Learning, Data Analysis, Experimental Design, Programming, Python, R, Scientific Literature, Statistics, Data Analysis, Microsoft Office, Attention to Detail, Analytical Skills, Research, Presentation Skills, and Team Collaboration. All three open positions are on-site. The Senior Scientist Mass Spectrometry (Proteomics) position will be based at the Oxford research facility. The Research Associate In Silico and Scientist/Sr./Principal Scientist, ADC & Translational Research positions are also located in Oxford. Here are some frequently asked questions about working at Oxford BioTherapeutics and the current job openings: 1. **What benefits are offered to employees at Oxford BioTherapeutics?** Benefits include private healthcare, a health cash plan, a generous pension scheme, a discretionary annual bonus scheme, free onsite parking, office snacks, enhanced holiday entitlement, an employee referral bonus program, an annual training budget for professional development, new hire share options, and team-building events and activities. 2. **What are the required qualifications for the Senior Scientist Mass Spectrometry (Proteomics) role?** A PhD in proteomics, mass spectrometry, protein biochemistry, or bio/analytical chemistry is required. Candidates must also be located in the Oxford/Oxfordshire area and have knowledge of running a mass spectrometry laboratory through post-doctoral work. 3. **What skills are essential for the Research Associate In Silico position?** Good knowledge of programming and an interest in developing these skills (e.g., Python, R), a Masters degree from a computational or biological related course, experience reading and summarizing scientific literature, and familiarity with Microsoft office (Excel, PowerPoint, Word). 4. **What experience is needed for the Scientist/Sr./Principal Scientist, ADC & Translational Research position?** A PhD in cancer biology, immuno-oncology, pharmacology, pharmaceutical sciences, or a related discipline is required. The role also requires experience with primary human cellular/tissue-based assays. 5. **What is the company culture like?** Oxford BioTherapeutics promotes a culture of innovation, responsibility, and commitment to goals. The people often describe OBT’s culture as friendly, collaborative, and hard-working.