Worcester
full-time
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Postdoctoral Position, Lawson Lab, UMass Chan Medical School
A postdoctoral position is available in the Lawson Lab at University of Massachusetts Chan Medical School, Department of Molecular, Cell, and Cancer Biology (lawsonlab.umassmed.edu). The Lawson Lab utilizes the zebrafish as a model system to study the development of the circulatory and lymphatic systems.
Current projects focus on two areas:
Developmental nature of vascular anomalies. Our goal is to determine how developmental defects associated with known mutations in humans result in defective vascular or lymphatic function. Studies include identifying relevant molecular targets, linking cellular mechanisms and defects to disease phenotypes, and small molecule screening to identify therapeutics.
Understanding vascular mural cell development. We seek to dissect transcriptional regulatory networks required for pericyte development. We have identified several candidate transcription factors and current efforts focus on genetic analysis of these candidates to determine how they regulate pericyte specification.
For all projects, we routinely develop and apply cutting-edge approaches, including conditional genetics, CRISPR-based gene editing, single cell molecular analyses, and in vivo time lapse.
The ideal candidate will have experience in molecular biology as documented through their publication record. Prior expertise in the application of genome editing in model systems is welcome and general experience with model organisms is preferred. Applicants must otherwise be highly motivated and technically accomplished as documented by exceptional publication record. Only those applicants accepted for initial consideration will be subsequently contacted for letters of reference.
A complete list of our recent and past work can be accessed at the following link: https://www.ncbi.nlm.nih.gov/myncbi/nathan.lawson.1/bibliography/public/
ForHealth Consulting partners with purposeful organizations, including state Medicaid agencies and health and human services organizations, to make the healthcare experience better for all – more equitable, effective, and accessible. We know that to do this, we need to address every aspect of the system – how we pay for it, how we manage information, and how we deliver quality care to everyone. As part of UMass Chan Medical School, we leverage world-class expertise to create transformational solutions across the health and human services system. ForHealth Consulting believes in the power of collaboration and a shared purpose – together, we can make healthcare better.
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