About this role
Fixed-term of 3 years | Part-time with 65%| Salary according to TV-L E13 | Institute of Molecular Tumor Biology (IMTB)
We are UKM. We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility.
To meet our high standards every day, we are looking forward to your scientific expertise at the Institute of Molecular Tumor Biology (IMTB). This institute is headed by Prof. Dr. Frank Rosenbauer, is an experimentally oriented medical research institute focused on understanding the molecular mechanisms of cell differentiation, tumor development, and immune cell function – ideally with you on board!
A major research focus is the role of transcription factors in hematopoietic cell fate regulation and their interaction with epigenetic mechanisms. We use state-of-the-art approaches, including next-generation sequencing, functional genetic screens, and transgenic model systems. Further information is available on our homepage and via our publications in leading journals such as Nature Immunology, Nature Genetics, The EMBO Journal, Blood and others.
The PhD project will focus on the transcription factor PU.1, a key regulator of myeloid and lymphoid development. Using cutting-edge technologies, the project aims to investigate how three-dimensional changes in PU.1 chromatin architecture influence cell fate decisions and leukemia development.
Applicants should hold a master’s degree in biology or biochemistry and have hands-on experience with tissue culture and standard molecular biology techniques. Basic proficiency in the R programming language and in working with public omics repositories is required, while experience working with laboratory mice is considered an advantage. An excellent command of the English language is essential.
For questions, please contact Prof. Frank Rosenbauer, E-Mail: [email protected]
We offer an international, collaborative research environment and aim to fill the position as soon as possible.
Applications should include a full CV, and the names of two referees. Apply now via our career portal by 25 February 2026.
Other facts
About Universitätsklinikum Münster
Universitätsmedizin Münster
Das Universitätsklinikum Münster steht für Spitzenmedizin in der deutschen Krankenhauslandschaft und gehört bundesweit zu den erfolgreichsten Maximalversorgern. Wir gestalten die Zukunft der Medizin zum Wohl unserer Patient*innen – durch Spitzenforschung, exzellente Lehre und modernste Krankenversorgung.
Karriere am UKM
Egal ob in der Pflege, im ärztlichen Bereich, in der Verwaltung oder Forschung: Wir sind immer auf der Suche nach neuen Kolleg*innen, die mit Begeisterung und neuen Ideen etwas Besonderes leisten und erleben wollen. Mit mehr als 11.800 Mitarbeitenden ist das UKM einer der größten Arbeitgeber in der Region mit über 60 Berufsbildern. Neben 34 Ausbildungen in medizinischen und nicht-medizinischen Berufen bietet das UKM drei duale Studiengänge ein Freiwilliges Soziales Jahr (FSJ) oder Praktisches Jahr (PJ). ukm.de/karriere
What you'll do
- The PhD project will focus on the transcription factor PU.1 and its role in cell fate decisions and leukemia development. The candidate will utilize cutting-edge technologies to investigate chromatin architecture changes.
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