Associate Scientist to Scientist of Biochemistry
full-time•Pudong
About this role
Job Title: Associate Scientist to Scientist of Biochemistry
Reports To: Sr. Scientist, Structural Biology
Location: Shanghai, China
About Us:
Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.
Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.
Position Summary:
In this role, you will join a motivated team of scientists contributing to pipeline projects with a focus on membrane protein expression and purification to support hit identification campaigns, like DEL and AS-MS to find novel hits molecules. In addition, you will also make contributions to structural biologists to help determine structures of drug targets in complex with molecules, to influence all stages of drug discovery. In addition, you will work closely with teams in other functional areas and with CROs.
Job Responsibilities:
- Conduct construct design for protein expression.
- Conduct GPCR purifications for cryo-EM structure determination while closely working with reagent team and CROs
- Provide qualified reagents to enable hit identification campaign while working closely with biophysical team
- Analyze, interpret, and report protein expression and purification data through meticulous record-keeping, data entry into electronic lab notebook
Qualifications:
- Core Competencies, Knowledge and Skill Requirements
- Knowledge in biochemistry and molecular biology
- Solid knowledge in protein expression and purification in multiple systems, including coli, insect cells and mammalian cells
- Hands-on experiences in protein expression and purification, experience on insect cells expression and membrane protein purification is a plus
- Hands-on experiences in molecular cloning. Experience in construct design and reagent optimization is a plus
- Experiences in biochemical experiments
- Knowledge in structural biology is a plus
- Communication & Interpersonal Skills
- Fluent in reading, writing, and speaking Chinese and English
- Ability to effectively collaborate in a dynamic environment
- Education and Experience
- Master’s degree or above in protein science, biochemistry, or biophysics
- Laboratory experiences of protein expression and purification
- Industry experience is a plus
Structure Therapeutics Inc. is an Equal-Opportunity Employer.
Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience.
At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, ongoing performance-based equity and various benefits offerings.
Notice to Recruiters/Staffing Agencies
Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees.
We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file.
Structure Therapeutics’ receipt or acceptance of an unsolicited resume submitted by a vendor organization to this website or employee does not constitute an actual or implied contract between Structure Therapeutics and such organization and will be considered unsolicited and Structure Therapeutics will not be responsible for related fees.
Fraud Alert
To all candidates: your personal information and online safety are a top priority for us. At Structure Therapeutics, direct candidates to apply through our official career page at BambooHR.
Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources.
Location
Shanghai, Pudong District
Department
102- Structural Biology
Employment Type
FTE
Minimum Experience
Experienced
What you'll do
- The role involves conducting protein expression and purification to support hit identification campaigns and collaborating with structural biologists to determine drug target structures. Additionally, the candidate will work closely with teams in other functional areas and CROs.
About Structure Therapeutics
Structure Therapeutics is a science-driven clinical-stage biopharmaceutical company focused on discovering and developing innovative oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Utilizing its next generation structure-based drug discovery platform, Structure Therapeutics has established a robust GPCR-targeted pipeline, featuring multiple wholly-owned proprietary clinical-stage small molecule compounds designed to surpass the scalability limitations of traditional biologic and peptide therapies and be accessible to more patients around the world.
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Frequently Asked Questions
What does a Associate Scientist to Scientist of Biochemistry do at Structure Therapeutics?
As a Associate Scientist to Scientist of Biochemistry at Structure Therapeutics, you will: the role involves conducting protein expression and purification to support hit identification campaigns and collaborating with structural biologists to determine drug target structures. Additionally, the candidate will work closely with teams in other functional areas and CROs..
Is the Associate Scientist to Scientist of Biochemistry position at Structure Therapeutics remote?
The Associate Scientist to Scientist of Biochemistry position at Structure Therapeutics is based in Pudong, Shanghai, China. Contact the company through Clera for specific work arrangement details.
How do I apply for the Associate Scientist to Scientist of Biochemistry position at Structure Therapeutics?
You can apply for the Associate Scientist to Scientist of Biochemistry position at Structure Therapeuticsdirectly through Clera. Click the "Apply Now" button above to start your application. Clera's AI-powered platform will help match your profile with this opportunity and guide you through the application process.