About this role
Genetics has furnished the parts list for vertebrate development but not the instructions necessary to assemble those parts and create an embryo. The Laboratory of Theoretical Condensed Matter Physics, led by Dr. Eric D. Siggia, studies embryonic stem cells from mice and humans using methods derived from biophysics that permit the self-organization potential of stem cells to manifest itself. The assays reveal how signaling pathways integrate cues across space and time to pattern the developing embryo.
Overview
We seek a highly motivated Bioinformatics Assistant to join the Laboratory of Theoretical Condensed Matter Physics. The primary responsibility will be to process time-lapse datasets of mouse embryos acquired using light-sheet microscopy.
Responsibilities
Responsibilities include the following:
- Use custom Python/MATLAB-based software developed in lab
- Correct nuclear segmentations generated by state-of-the-art deep learning models
- Classify cell types
- Refine lineage tracking trees
- Will learn/apply computational geometry techniques to extract 3D embryo structure
Qualifications
REQUIRED QUALIFICATIONS:
- Bachelor’s degree in Computational Biology, Computer Science, Bioinformatics, Biostatistics, Mathematics, or related field
PREFERRED QUALIFICATIONS:
- Interest in biology/ biomedical research
- Coding experience
The Rockefeller University is an equal opportunity employer – veterans/individuals with disabilities. Qualified applicants will receive consideration for employment without regard to characteristics protected by applicable local, state or federal law, including but not limited to disability and protected veteran status.
The salary of the finalist selected for this role will be set based on various factors, including but not limited to organizational budgets, qualifications, experience, education, licenses, specialty, and training. The hiring range provided represents The Rockefeller University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Compensation Range: Min
USD $50,000.00/Yr.
Compensation Range: Max
USD $55,000.00/Yr.
Other facts
About Rockefeller University
Rockefeller University Press (RUP) is committed to quality and integrity in scientific publishing. We use the latest technologies and carry out rigorous peer review, applying the highest standards of novelty, mechanistic insight, data integrity, and general interest to fulfill our mission of publishing excellent science. RUP publishes Journal of Cell Biology (JCB), Journal of Experimental Medicine (JEM), and Journal of General Physiology (JGP), and co-publishes Life Science Alliance (LSA). RUP’s nonprofit journals were established by the research community, and editorial decisions and policies continue to be driven by scientists who actively contribute to their fields, appreciate the value of peer review, and desire a better publication experience for all. RUP journals publish groundbreaking research in the life sciences and biomedicine from leading investigators around the world and serve as a valued resource to those engaged in cutting-edge research and who train future generations of scientists. RUP is based in New York City and is a department of The Rockefeller University, a leading biomedical research university dedicated to conducting innovative, high-quality research to improve the understanding of life for the benefit of humanity.
What you'll do
- The Bioinformatics Assistant will process time-lapse datasets of mouse embryos using custom software. Responsibilities include correcting nuclear segmentations, classifying cell types, and refining lineage tracking trees.
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