Location: London, UK (Laboratory based- role)

Reporting to: Principal Scientist, Global Technical Development

Job Summary

Reporting to the Principal Scientist, Global Technical Development, the Associate Scientist will contribute towards laboratory-based activities supporting lentiviral vector (LVV) process development. Under supervision, the Associate Scientist will execute upstream and downstream process studies, vector analytics, and generation of high-quality technical documentation, while collaborating with cross-functional teams to support development, technology transfer, and CMC deliverables across the programmes.

Key Elements and Responsibilities

Core Activities

Lab maintenance

Broader Technical Development & CMC Exposure

Required Knowledge

·         Experience in biotechnology/biological sciences or equivalent. Experience in cell and gene therapy is highly desirable.

·         Understanding of vector manufacturing process operations including cell culture (adherent and/or suspension platforms), filtration, chromatography and tangential flow filtration operations. Practical experience in at least 2 of the above process steps is required.  

·         Understanding of analytical methods associated with gene therapy vectors and /or autologous gene-modified cellular therapies. Practical experience in vector analytics is highly desirable.

·         Confident in performing various laboratory techniques, especially in aseptic culturing, with the ability to quickly learn and develop new practical skills.

Skills and Abilities

·         Excellent interpersonal skills

·         Outstanding organizational skills

·         Excellent written and oral communication skills

·         Creative problem solver

·         Ability to operate in a fast-paced, multi-disciplinary industrial environment

Education

·         A minimum of BSc or equivalent in bioprocessing, biological sciences, gene therapy or related subject.