Noblis is seeking a postdoctoral candidate with a strong background in life science bioinformatics and synthetic biology to work with Noblis subject matter experts and scientists. The ideal candidate will develop and maintain bioinformatics pipelines for multiomics integration (genomics, transcriptomics, and proteomics) while leveraging AI to drive hypothesis generation, biomarker discovery, and de novo protein design.

This is a full-time, one-year fellowship position with the option for a second year, with potential opportunity to join Noblis as a full-time employee.

Responsibilities:

• Develop and maintain AI-driven bioinformatics platforms (integration pipelines, visualization tools, foundation models, and LLMs)
• Design and implement workflows for DNA/RNA extraction, next generation sequencing (NGS), and bioinformatic analytics including engineered detection systems
• Participate in the innovation, design, and development of statistical and analytical solutions that are reproducible.
• Exercise independent judgment in developing methods, techniques, and evaluation criteria for research and data analyses.
• Clearly articulate research findings in peer-reviewed publications, grants, proposals, white papers, and presentations.
• Actively participate in scientific/industry symposiums, conferences, and professional societies.
• Work both autonomously and collaboratively with a positive collegial attitude.

• PhD degree in Bioinformatics, Computational Biology, Data Science, Biostatistics, Computer Science, Biology or a related field granted soon or within the last 5 years

• The candidate must be a U.S. citizen with a government clearance or the ability to obtain one.

• Familiarity with next-generation sequencing platforms (e.g., Illumina, Pacific Biosciences, Oxford Nanopore Technologies) and associated data types
• Strong analytical skills with experience in applying and/or developing methods for analyzing various types of –omics data (genomics, transcriptomics, proteomics, or metabolomics)
• Fluency in multiple programming languages, including UNIX/Linux, Python and R, for small- and large-scale tool development.
• Experience deploying externally facing, reproducible code and deliverables including use of Git/GitHub/Atlassian systems.
• Strong organizational skills with ability to efficiently manage time, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Excellent communication skills and an ability to explain highly technical concepts to non-experts.
• A desire for publishing in relevant scientific journals.
• High degree of ethical and scientific standards.

• Experience with machine learning frameworks (e.g., TensorFlow, PyTorch) for biological data analysis
• Knowledge of protein structure prediction tools and protein design algorithms
• Experience with containerization technologies (Docker, Singularity, Kubernetes)
• Familiarity with cloud computing environments (AWS, Azure, GCP)
• Database management skills (SQL, NoSQL)
• Experience with high-performance computing environments
• Knowledge of statistical methods for experimental design and data analysis
• Background in structural bioinformatics and molecular modeling

Preferred:

• Experience developing workflows using a workflow language (e.g., Snakemake, Nextflow, CWL)
• Experience with de novo protein design principles and enzyme kinetics
• Experience with molecular dynamics simulations

Noblis and our wholly owned subsidiaries, Noblis ESI, and Noblis MSD tackle the nation's toughest problems and apply advanced solutions to our clients' most critical missions. We bring the best of scientific thought, management, and engineering expertise together in an environment of independence and objectivity to deliver enduring impact on federal missions. Noblis works with a wide range of government clients in the defense, intelligence and federal civil sectors. Learn more at Noblis -About Us

Why work at a Noblis company?

Our employees find greater meaning in their work and balance the other things in life that matter to them. Our people are our greatest asset. They are exceptionally skilled, knowledgeable, team-oriented, and mission-driven individuals who want to do work that matters and benefits the public. Noblis has won numerous workplace awards. Noblis maintains a drug-free workplace.

*Remote/hybrid status is subject to change based on Noblis and/or government requirements

All qualified applicants will receive consideration for employment without regard to race, color, ethnicity, sex, age, national origin, religion, physical or mental disability, pregnancy/childbirth and related medical conditions, veteran or military status, or any other characteristics protected by applicable federal, state, or local law.

If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact us.

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At Noblis we recognize and reward your contributions, provide you with growth opportunities, and support your total well-being. Our offerings include health, life, disability, financial, and retirement benefits, as well as paid leave, professional development, tuition assistance, and work-life programs. Our award programs acknowledge employees for exceptional performance and superior demonstration of our service standards. Full-time and part-time employees working at least 20 hours a week on a regular basis are eligible to participate in our benefit programs. Other offerings may be provided for employees not within this category. We encourage you to learn more about our total benefits by visiting the Benefits page on our Careers site.

Compensation at Noblis is determined by various factors, including but not limited to, the combination of education, certifications, knowledge, skills, competencies, and experience, internal and external equity, location, clearance level, as well as contract-specific affordability, organizational requirements and applicable employment laws. The projected compensation range for this position is based on full time status. For part time or on-call staff, compensation is proportionately adjusted based on hours worked. While monetary compensation is important, it's just one component of Noblis’ total compensation package.